Clinical investigation of neuromuscular transmission

神经肌肉传递的临床研究

• 批准号: 09671593
• 负责人: UEDA Naoyuki
• 金额: $ 1.73万
• 依托单位: Kurume University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671593/
• 关键词: neuromuscular monitoring; mechanomyograph; electromyograph; エレクトロマイオグラフ; メカノマイオグラフ; 筋弛緩薬

Train-of-four (TOF) responses by electromyogram with M-NMT^<<does not result in>8> and by force of acceleration mechanomyogram with Myograph 2000^<<does not result in>8>were simultaneously measured in 22 adult patients receiving vecuronium under sevoflurane- nitrous oxide anesthesia supplemented with fentanyl. The regression equations of T, and TOF ratio between the force mechanogram (X) and the electromyogram (Y) were Y = 0.880X +4.972 (r^2=0.952, n=245) and Y=0.923X+4.885 (r^2=0.942, n=314), respectively. The regression equations of T_1and TOF ratio between the acceleration mechanogram (X) and the electromyograph (Y) were Yr^2=0.861 X + 7.584 (r^2 = 0.940, n = 253) and Y = 0.882X + 1.05 (r2 = 0.903, n = 337), respectively. There was a good positive linier correlation in both T_1and TOF ratio between the electromyogram and the force or acceleration mechanomyogram. In conclusion. the new electromyogram of M-NMT is not only easier in hadling but is as reliable as the conventional mechanomyogram of Myograph 2O0O^<<does not result in>8>.

在七氟醚-氧化亚氮复合芬太尼麻醉下，22例成人患者同时测定了肌电M-NMT和肌电加速图肌电不能产生的四列反应(TOF)。力机械图(X)与肌电图(Y)的T和TOF比值的回归方程分别为Y=0.880X+4.972(r^2=0.952，n=245)和Y=0.923X+4.885(r^2=0.942，n=314)。加速度机械图(X)和肌电图仪(Y)的T1和TOF比值的回归方程分别为Yr^2=0.861 X+7.584(r^2=0.940，n=253)和Y=0.882 X+1.05(R2=0.903，n=337)。肌电T_1和TOF比值与力或加速度机械肌图呈良好的直线正相关。总而言之。新的M-NMT肌电图不仅易于操控，而且与传统的肌图仪肌电图一样可靠，不会导致&gt；

项目成果

Ueda N,Masuda Y,Yamada S: "Monitoring the function of neuromuscular junction : what does it tell us?" LiSA. 3(5). 418-424 (1996)

Ueda N、Masuda Y、Yamada S：“监测神经肌肉接头的功能：它告诉我们什么？”

上田直行,増田裕一,山田信一 濱田伸哉,新山修平,加納龍彦: "新しい筋弛緩モニターユニット(M-NMT^<【encircledR】>)とその臨床的有用性" 臨床麻酔. 21・10. 1617-1621 (1997)

Naoyuki Ueda、Yuichi Masuda、Shinichi Yamada、Shinya Hamada、Shuhei Niiyama、Tatsuhiko Kano：“新型肌肉松弛监测装置（M-NMT^<[encircledR]>）及其临床实用性”临床麻醉 21・10。 (1997)

上田直行: "Clinical assessment of neuromuscular transmission" 日本臨床麻酔学会誌. 11・11. 197-201 (1995)

Naoyuki Ueda：“神经肌肉传递的临床评估”日本临床麻醉学会杂志 11・11（1995）。

Masuda Y,Ueda N,Yamada S,et al (3): "Interaction between propofol anesthesia and vecuronium-induced muscle relaxation in man." J Clin Anesth. 21(10). 1512-1524 (1997)

Masuda Y、Ueda N、Yamada S 等人 (3)：“丙泊酚麻醉与维库溴铵诱导的人体肌肉松弛之间的相互作用。”

上田直行, 増田裕一, 山田信一 他3名: "新しい筋弛緩モニターユニット(M-NMT^<(R)>)とその臨床的有用性" 臨床麻酔. 21・10. 1617-1621 (1997)

Naoyuki Ueda、Yuichi Masuda、Shinichi Yamada 等 3 人：“新型肌肉松弛监测装置 (M-NMT^<(R)>) 及其临床实用性”临床麻醉 21・10。