The study of the fetal heart rates changes in hypoxemia by spectral analysis

低氧血症胎心率变化的频谱分析研究

• 批准号: 09671189
• 负责人: KIMURA Yoshitaka
• 金额: $ 1.28万
• 依托单位: TOHOKU UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09671189/
• 关键词: Power spectrum; Fetal distress; High frequency area; HF領域; 羊実験モデル; 胎児心拍数; パワースペクトル成分; 低酸素血症; ドプラ; スペクトル解析; 胎児生理学

The purposes of this study were to clarify the change of the fetal heart rate variability by using power spectral analysis in fetal distress. In 1998 we studied experimentally the change of fetal heart rate spectral structure of lamb under repeated umbilical cord occlusions. It was known that the power spectrum is constructed with two main frequency areas, one is low frequency area (about 0.1 Hz), which changes correlating with the sympathetic nervous system in fetal lamb, another is high frequency area (about 0.3-0.5 Hz), which is partially correlating with parasympathetic nervous system. In this year we found that the mode of the low frequency area during 1 hour is decreasing in fetal hypoxemia. And the high frequency area, which changes corresponding with the low frequency area in normal condition, changed differently than the low frequency area in hypoxemia. Especially the transient increase of frequency area was frequently noticed only in high frequency area in severe hypoxemia.

本研究旨在探讨胎儿窘迫时胎心率变异性的功率谱变化。1998年，我们对反复脐带阻断羔羊胎心率频谱结构的变化进行了实验研究。已知功率谱由两个主要频率区构成，一个是与胎羊交感神经系统相关的低频区(约0.1赫兹)，另一个是高频区(约0.3-0.5赫兹)，部分与副交感神经系统相关。今年我们发现胎儿低氧血症1小时内低频区模式减少。正常情况下与低频区对应变化的高频区与低氧血症时的低频区变化不同。尤其是重度低氧血症时，频域的一过性增加多见于高频区。

项目成果

木村芳孝: "妊娠中期胎児心拍ゆらぎの周波数成分の仮死による構造変化"周産期学シンポジウム NO.17. 17. 47-51 (1999)

Yoshitaka Kimura：“由于窒息导致的妊娠中期胎儿心跳波动的频率成分的结构变化”围产学研讨会第 17 号。17. 47-51 (1999)。

渡辺孝紀: "間欠的及び持続的臍帯圧迫による胎児循環動態脳血流量の変化" 日本産婦人科・新生児血流学会誌. 8巻2号. 57-58 (1998)

Takanori Watanabe：“间歇性和持续性脐带压迫引起的胎儿血流动力学和脑血流的变化”日本妇产科和新生儿血流学会杂志，第 8 卷，第 2 期，57-58（1998 年）。