Evaluation of coronary blood flow by transthoracic Doppler echocardiography

经胸多普勒超声心动图评估冠状动脉血流

• 批准号: 09670745
• 负责人: NASU Masataka
• 金额: $ 1.15万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09670745/
• 关键词: Transthoracic Doppler echocardiography; Coronary blood flow; Coronary artery stenosis; Coronary blood flow reserve; 経胸壁ドプラ心エコー図法

Although it was. difficult to visualize epicardia1 coronary artery blood by transthoracic echocardiography, recent development of ultrasound instrument enable to visualize epicardial artery flow. We investigated the detection rate oLthe coronary artery blood flow and studied the diagnostic efficacy of coronary artery stenosis by transthoracic Doppler echocardiography using Sequoia system.The highly sensitive color and pulsed Doppler echo allowed efficient detection not only of the left anterior descending coronary artery (LAD), but also the proximal portion of the left circumflex artery. It was found that the coronary blood flow reserve (CFR) of LAD measured by transthoracic Doppler echocardiography was comparable in accuracy with CFR measured by invasive methods (r=0.87, p<0.0001).Coronary flow mapping in LAD was performed by the color Doppler-guided pulsed Doppler and diastolic mean velocity ratio (DMVR) in LAD was calculated from highest diastolic mean velocity (HDMV) and lowest diastolic mean velocity (LDMV) (DMVR = HDMV/ LDMV). When DMVR was 2.0 or more which was regarded as an abnormally high value, stenotic lesion with 50% diameter stenosis (DS) or more DS was diagnosed with 93% sensitivity and 93 % specificity.The good collateral coronary blood flow through the septal branches from right coronary artery to LAD was visualized by transthoracic color Doppler echocardiography.Highly sensitive transthoracic Doppler echocardiography was very useful to evaluate non.invasively and accurately coronary stenosis.

虽然是。通过经胸超声心动图难以显示心外膜冠状动脉血液，最近超声仪器的发展使得能够显示心外膜动脉血流。本文应用Sequoia系统经胸多普勒超声心动图对冠状动脉血流的检出率及冠状动脉狭窄的诊断价值进行了研究，其高灵敏度的彩色和脉冲多普勒不仅能有效地检出冠状动脉左前降支（LAD），而且能有效地检出左回旋支近端。结果表明，经胸多普勒超声心动图测定左前降支冠状动脉血流储备（CFR）的准确性与有创法相当（r=0.87，p<0.0001）。通过彩色多普勒引导脉冲多普勒进行LAD的冠状动脉血流图，并根据最高舒张期平均速度（HDMV）计算LAD的舒张期平均速度比（DMVR）最低舒张期平均血流速度（LDMV）（DMVR = HDMV/ LDMV）。当DMVR为2.0或更大时，其被认为是异常高的值，直径狭窄（DS）≥ 50%的狭窄病变诊断敏感性为93%，经胸彩色多普勒超声心动图可显示从右冠状动脉到LAD的间隔支的良好侧支冠状动脉血流，高灵敏度经胸多普勒超声心动图可用于无创、准确地评价冠状动脉狭窄程度。

项目成果

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Kuriki S.Nasu M.et al.：“通过经胸多普勒超声心动图无创测量左冠状动脉血流储备”循环。

Kuriki S,Nasu M et al: "Noninvasive measurement of lft coronary blood flow reserve by transthoracic Doppler echocardiography" Circulation. 96(suppl). I・703 (1997)

Kuriki S、Nasu M 等人：“经胸多普勒超声心动图无创测量左冠血流储备”循环 96（增刊）。

那須雅孝・平盛勝彦: "非侵襲的冠動脈描出法の進歩" Heart View. 12巻12号. 34-38 (1998)

Masataka Nasu 和 Katsuhiko Hiramori：“非侵入性冠状动脉可视化的进展”《Heart View》第 12 卷，第 12 期。34-38 (1998)

Kuriki S, Nasu M.et al: "Noninvasive measurement of left coronary blood flow reserve by transthoracic Doppler echocardiography" Circulation. 96(suppl). I・703 (1997)

Kuriki S、Nasu M.等人：“经胸多普勒超声心动图对左冠状动脉血流储备的无创测量”循环 96（增刊）。

Tashiro A,Nasu M et al: "Non-invasive diagnosis after coronary intervention to left anterior descending artery lesion by transthoracic Dopper coronary echo" Circulation. 98(suppl). I-163 (1998)

Tashiro A，Nasu M等：“通过经胸多普勒冠状动脉回声对冠状动脉介入治疗后左前降支病变进行无创诊断”循环。