Anatomical and physiological studies of mushroom body neurons of an insect.

昆虫蘑菇体神经元的解剖学和生理学研究。

基本信息

  • 批准号:
    09640800
  • 负责人:
  • 金额:
    $ 1.92万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    1997
  • 资助国家:
    日本
  • 起止时间:
    1997 至 1999
  • 项目状态:
    已结题

项目摘要

The mushroom body (MB) is a conspicuous neuropil structure in the insect brain, and is critical to various forms of associative memory. In the present study,1. Activities of MB output neurons of freely behaving cockroaches, Periplaneta americana, were examined. Insulated copper wires of 14-20 μm in diameter were implanted chronically into the MB output neuropil, and unit activity was differentially recorded while the cockroach walked freely in an arena. After the recording, copper ions were impregnated by passing a positive current to mark the location of electrode tips. The 41 units recorded in the present study were classified into (1 ) sensory neurons which responded to visual, olfactory and/or tactile stimuli, (2) motor-related neurons which were active during locomotion, (3) sensory-motor neurons which were active during sensory stimulation and also during motor action. Some motor-related neurons exhibited activity preceding the initiation of specific locomotory action for 0.2-1 sec. These results suggest that the MB integrate various sensory and motor signals and form preparatory signals for voluntary locomotory actions.2. Dendritic morphology of output neurons of cockroach MB was studied by means of Golgi stainings and by injecting Lucifer Yellow into the neurons. Some neurons had dendrites which interact only with a specific combination of modular subunits of the MBs.3. The ability of cockroaches and crickets (Glyllus bimaculatus) to associate peppermint with reward and vanilla with non-reward was examined. In both insects, a single trial was sufficient to change the initial odor preference, and memory formed by three-time training retained for at least seven days. The results showed that both species have excellent ability to learn odors and are suited as materials to study neural basis of olfactory learning in insects.
蘑菇体(MB)是昆虫脑中一个重要的神经元结构,对各种形式的联想记忆起着关键作用。在本研究中,1.研究了自由活动美洲大蠊(Periplaneta americana)的MB输出神经元的活动。将直径为14-20 μm的绝缘铜线长期植入MB输出神经元,在蟑螂自由行走于竞技场的同时,差分记录单位活动。在记录之后,通过使正电流通过来浸渍铜离子以标记电极尖端的位置。在本研究中记录的41个单位分为:(1)感觉神经元,响应视觉,嗅觉和/或触觉刺激,(2)运动相关的神经元,在运动过程中活跃,(3)感觉运动神经元,在感觉刺激和运动过程中也活跃。一些运动相关神经元在特定运动动作开始前表现出活动,持续0.2-1秒。这些结果表明,MB整合了各种感觉和运动信号,并为自主运动行为形成准备信号。用高尔基体染色法和荧光黄注射法研究了蟑螂MB输出神经元的树突形态。一些神经元的树突只与特定的MBs模块化亚基组合相互作用。研究了蟑螂和蟋蟀(Glyllus bimaculatus)将薄荷与奖励和香草与非奖励联系起来的能力。在这两种昆虫中,一次试验就足以改变最初的气味偏好,并且通过三次训练形成的记忆至少保留了七天。结果表明,这两种昆虫都具有良好的气味学习能力,适合作为研究昆虫嗅觉学习神经基础的材料。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
M.Mizunami他3名: "Topography of modular subunits in the mushroom bodies of the cockroach"J.Comp.Neurol.. 399. 153-161 (1998)
M.Mizunami 和其他 3 人:“蟑螂蘑菇体内模块化亚基的拓扑结构”J.Comp.Neurol.. 399. 153-161 (1998)
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
M.Mizunami他3名: "Topography of four classes of Kenyon cells in the mushroom bodies of the cockroach"J.Comp.Neurol.. 399. 162-175 (1998)
M.Mizunami 和其他 3 人:“蟑螂蘑菇体中四类 Kenyon 细胞的拓扑结构”J.Comp.Neurol.. 399. 162-175 (1998)
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
水波誠他29名: "実験室の小さな生きものたち"羊土社. 165 (1999)
Makoto Mizunami 等 29 人:《实验室里的小生物》Yodosha 165 (1999)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
水波 誠: "実験室の小さな生ものたち"羊土社. 165 (1999)
水波诚:《实验室里的小生物》Yodosha 165 (1999)
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
H.Nishino,M.Mizunami: "Giant input neurons of the mushroom body : intracellular recording and staining in the cockroach"Neurosci.Lett.. 246. 57-60 (1998)
H.Nishino,M.Mizunami:“蘑菇体的巨型输入神经元:蟑螂的细胞内记录和染色”Neurosci.Lett.. 246. 57-60 (1998)
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

MIZUNAMI Makoto其他文献

MIZUNAMI Makoto的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('MIZUNAMI Makoto', 18)}}的其他基金

Novel approaches to insect learning systems using transgenic crickets
使用转基因蟋蟀构建昆虫学习系统的新方法
  • 批准号:
    24657049
  • 财政年份:
    2012
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Demonstration and extension of Mizunami-Unoki learning model.
Mizunami-Unoki学习模型的演示和扩展。
  • 批准号:
    24370030
  • 财政年份:
    2012
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Neural basis of cognitive processes underlying insect learning
昆虫学习认知过程的神经基础
  • 批准号:
    21370028
  • 财政年份:
    2009
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Roles of reward system and punishment system in insect learning
奖励系统和惩罚系统在昆虫学习中的作用
  • 批准号:
    18370027
  • 财政年份:
    2006
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Analysis of the roles of NO-cGMP signaling cascade for long-term memory formation in an insect.
分析 NO-cGMP 信号级联对昆虫长期记忆形成的作用。
  • 批准号:
    15370031
  • 财政年份:
    2003
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Neural Organization of the Protocerebrum of an Insect
昆虫原大脑的神经组织
  • 批准号:
    12640658
  • 财政年份:
    2000
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Neural mechanisms of olfactory learning in insect 'Microbrain'
昆虫“微脑”嗅觉学习的神经机制
  • 批准号:
    11168201
  • 财政年份:
    1999
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research on Priority Areas (A)
Roles of the mushroom body in locomotory control in an insect
蘑菇体在昆虫运动控制中的作用
  • 批准号:
    07640895
  • 财政年份:
    1995
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

相似海外基金

Representation of " Colour " in insect brain - neural processing of wavelength information in the mushroom body -
昆虫大脑中“颜色”的表征——蘑菇体内波长信息的神经处理——
  • 批准号:
    22H02356
  • 财政年份:
    2022
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Transcriptional regulation, neuronal development, and function of the mushroom body in a Drosophila model of intellectual disability
智力障碍果蝇模型中的转录调节、神经元发育和蘑菇体的功能
  • 批准号:
    10056231
  • 财政年份:
    2018
  • 资助金额:
    $ 1.92万
  • 项目类别:
The mechanisms of connectivity and function underlying multisensory integration in the Drosophila melanogaster mushroom body
果蝇蘑菇体内多感觉整合的连接和功能机制
  • 批准号:
    10204131
  • 财政年份:
    2018
  • 资助金额:
    $ 1.92万
  • 项目类别:
The mechanisms of connectivity and function underlying multisensory integration in the Drosophila melanogaster mushroom body
果蝇蘑菇体内多感觉整合的连接和功能机制
  • 批准号:
    9791010
  • 财政年份:
    2018
  • 资助金额:
    $ 1.92万
  • 项目类别:
The mechanisms of connectivity and function underlying multisensory integration in the Drosophila melanogaster mushroom body
果蝇蘑菇体内多感觉整合的连接和功能机制
  • 批准号:
    10468042
  • 财政年份:
    2018
  • 资助金额:
    $ 1.92万
  • 项目类别:
Transcriptional regulation, neuronal development, and function of the mushroom body in a Drosophila model of intellectual disability
智力障碍果蝇模型中的转录调节、神经元发育和蘑菇体的功能
  • 批准号:
    10300046
  • 财政年份:
    2018
  • 资助金额:
    $ 1.92万
  • 项目类别:
Transcriptional regulation, neuronal development, and function of the mushroom body in a Drosophila model of intellectual disability
智力障碍果蝇模型中的转录调节、神经元发育和蘑菇体的功能
  • 批准号:
    9679001
  • 财政年份:
    2018
  • 资助金额:
    $ 1.92万
  • 项目类别:
Comprehensive mapping of odor-evoked activity underlying presynaptic plasticity in compartmentalized axonal lobes of Drosophila mushroom body
果蝇蘑菇体区室化轴突叶突触前可塑性下气味诱发活动的综合绘图
  • 批准号:
    17K17681
  • 财政年份:
    2017
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Experience-dependent odor representations in the Drosophila mushroom body
果蝇蘑菇体内依赖于经验的气味表征
  • 批准号:
    25430026
  • 财政年份:
    2013
  • 资助金额:
    $ 1.92万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Activity-dependent modulation of the Drosophila mushroom body function by FMRP
FMRP 对果蝇蘑菇体功能的活性依赖性调节
  • 批准号:
    8398504
  • 财政年份:
    2012
  • 资助金额:
    $ 1.92万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了