Relationship between the peripheral neuropathy due to anticancer drugs and vibration sense or nerve conduction velocity in cancer patients

癌症患者抗癌药物引起的周围神经病变与振动觉或神经传导速度的关系

• 批准号: 15K08675
• 负责人: Shirao Kuniaki
• 金额: $ 2.25万
• 依托单位: Oita University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2015
• 资助国家: 日本
• 起止时间: 2015-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K08675/
• 关键词: 抗がん剤; 副作用; しびれ; 音叉検査値; 神経伝導速度; 末梢神経障害; オキサリプラチン; パクリタキセル; 抹消神経障害; 組織変異; 遺伝子多型; 軸索密度

项目成果

Randomized phase II study of second-line chemotherapy with the best available 5-fluorouracil regimen versus weekly administration of paclitaxel in far advanced gastric cancer with severe peritoneal metastases refractory to 5-fluorouracil-containing regime

随机 II 期研究，采用最佳可用 5-氟尿嘧啶方案与每周给予紫杉醇治疗对 5-氟尿嘧啶方案无效的严重腹膜转移的晚期胃癌进行二线化疗

• 发表时间: 2015
• 期刊: Gastric Cancer.
• 作者: Nishina T;Boku N;Gotoh M;Shimada Y;Hamamoto Y;Yasui H;Yamaguchi K;Kawai H;Nakayama N;Amagai K;Mizusawa J;Nakamura K;Shirao K;Ohtsu A; Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group
• 通讯作者: Ohtsu A; Gastrointestinal Oncology Study Group of the Japan Clinical Oncology Group

A randomized phase II study of combination therapy with S-1, oral leucovorin, and oxaliplatin (SOL) and mFOLFOX6 in patients with previously untreated metastatic colorectal cancer

• DOI: 10.1007/s00280-015-2676-0
• 发表时间: 2015-03-01
• 期刊: CANCER CHEMOTHERAPY AND PHARMACOLOGY
• 影响因子: 3
• 作者: Yamazaki, Kentaro;Kuwano, Hiroyuki;Boku, Narikazu
• 通讯作者: Boku, Narikazu