Advancing 4D fluorescence microscopy within Australia

这项多机构提案的目标是在南澳大利亚州建立一个最先进的光片显微镜设施，增强分析基础设施和全国用户支持网络。预期是，这将通过促进对新的生物过程的高分辨率四维询问来改变多学科的研究结果。重大的好处将包括能够在不引起植物毒性的情况下，在长时间尺度上对活组织的深层进行成像，以产生高影响的基本和可翻译的结果，开发新的探测和方法，新的跨学科合作，以及新的和独特的资金、学生培训和公共参与机会。

This multi-institutional proposal aims to establish a state-of-the-art Lightsheet microscope facility in South Australia with enhanced analysis infrastructure and a national user support network. Expectations are, this will transform researcher outcomes for multiple disciplines by facilitating high-resolution four-dimensional interrogation of novel biological processes. Significant benefits will include the ability to image deep within living tissue over long time-scales without inducing phytotoxicity to produce high-impact fundamental and translatable outcomes, the development of novel probes and methodologies, new cross-disciplinary collaborations, and new and unique funding, student training and public engagement opportunities.