Translational research toward drug discovery of leukemia
Translational research toward drug discovery of leukemia
批准号:
25293218
负责人:
NAOE Tomoki
金额:
$11.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2013
资助国家:
日本
项目状态:
已结题
起止时间:
2013-04-01 至 2016-03-31
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リツキシマブ併用化学療法に抵抗性を示すDLBCL症例を予測するバイオマーカーと治療層別化の可能性
预测对利妥昔单抗联合化疗耐药的 DLBCL 病例的生物标志物以及治疗分层的可能性
DOI:
--
发表时间:
2014
期刊:
影响因子:
--
作者:
[Yasuma K, Yasunaga JI, Takemoto K, Sugata K, Takenouchi N, Nakagawa M, Suzuki Y, and Matsuoka M., 冨田章裕]
通讯作者:
冨田章裕
A novel STAT inhibitor, OPB-31121, has a significant anti-tumor effect on STAT-dependent leukemia.
一种新型STAT抑制剂OPB-31121对STAT依赖性白血病具有显着的抗肿瘤作用。
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Fumihiko Hayakawa, Keiki Sugimoto, Shingo Kurahashi, Tomoki Naoe.]
通讯作者:
Tomoki Naoe.
Efficacy of ofatumumab against rituximab-resistant B-CLL/SLL cells with low CD20 protein expression.
ofatumumab 对具有低 CD20 蛋白表达的利妥昔单抗耐药 B-CLL/SLL 细胞的功效。
DOI:
10.1111/bjh.12857
发表时间:
2014
期刊:
Br J Haematol
影响因子:
--
作者:
[Shimada K, Tomita A, Saito S, Kiyoi H.]
通讯作者:
Kiyoi H.
Ph陽性ALL新規治療薬発見のためのPDXスクリーニングによるドラッグリポジショニング.
使用 PDX 筛选进行药物重新定位,以发现 Ph 阳性 ALL 的新治疗药物。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[森下喬允, 早川文彦, 杉本慶樹, 直江知樹, 清井仁.]
通讯作者:
清井仁.
1353 Development of FF-10101, a Novel Irreversible FLT3 Inhibitor, Which Overcomes Drug Resistance Mutations.
1353 开发 FF-10101,一种新型不可逆 FLT3 抑制剂,可克服耐药性突变。
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Toshiyuki Nakatani,Ken Uda, Takeshi Yamaura, Masaru Takasaki, Akimi Akashi, Fangli Chen, Yuichi Ishikawa, Fumihiko Hayakawa, Shinji Hagiwara, Hitoshi Kiyoi, and Tomoki Naoe]
通讯作者:
and Tomoki Naoe
共 41 条
Development of innovative anti-tumor agents that target signal transducers and activator of transcription
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批准号:23659487
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
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负责人:NAOE Tomoki
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依托单位:
Basic research aimed at understanding and overcoming of the primary and secondary resistance in molecular target therapy
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批准号:22390192
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
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财政年份:2010
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负责人:NAOE Tomoki
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依托单位:
Molecular mechanisms and therapeutic approach of residual leukemia
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批准号:19390261
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
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财政年份:2007
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负责人:NAOE Tomoki
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依托单位:
Research & Development of molecular target therapy for leukemia and Its assessment System
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批准号:17016029
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$29.38万
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财政年份:2005
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负责人:NAOE Tomoki
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依托单位:
Analysis of aberrant signal tansduction in hematological malignancy and development of treatment methods.
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批准号:16390276
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.81万
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财政年份:2004
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负责人:NAOE Tomoki
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依托单位:
Establishment of a leukemia model mouse by introducing mutated FLT3 gene
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批准号:13671058
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.62万
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财政年份:2001
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负责人:NAOE Tomoki
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依托单位:
Involvement of Fas ligand-independent caspase8 activation in AsィイD22ィエD2OィイD23ィエD2-induced apoptosis
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批准号:10670940
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.6万
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财政年份:1998
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负责人:NAOE Tomoki
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依托单位:
海外基金