A molecular mechanism of atopic manifestations of hyper-IgE syndrome

高 IgE 综合征特应性表现的分子机制

• 批准号: 25293232
• 负责人: MINEGISHI Yoshiyuki
• 金额: $ 11.81万
• 依托单位: The University of Tokushima
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2013
• 资助国家: 日本
• 起止时间: 2013-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25293232/
• 关键词: 原発性免疫不全症; アトピー性皮膚炎; STAT3; 高IgE症候群; 免疫不全症; アレルギー; 免疫学

项目成果

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome.

• DOI: 10.1084/jem.20140280
• 发表时间: 2015-09-21
• 期刊: The Journal of experimental medicine
• 作者: Kreins AY;Ciancanelli MJ;Okada S;Kong XF;Ramírez-Alejo N;Kilic SS;El Baghdadi J;Nonoyama S;Mahdaviani SA;Ailal F;Bousfiha A;Mansouri D;Nievas E;Ma CS;Rao G;Bernasconi A;Sun Kuehn H;Niemela J;Stoddard J;Deveau P;Cobat A;El Azbaoui S;Sabri A;Lim CK;Sundin M;Avery DT;Halwani R;Grant AV;Boisson B;Bogunovic D;Itan Y;Moncada-Velez M;Martinez-Barricarte R;Migaud M;Deswarte C;Alsina L;Kotlarz D;Klein C;Muller-Fleckenstein I;Fleckenstein B;Cormier-Daire V;Rose-John S;Picard C;Hammarstrom L;Puel A;Al-Muhsen S;Abel L;Chaussabel D;Rosenzweig SD;Minegishi Y;Tangye SG;Bustamante J;Casanova JL;Boisson-Dupuis S
• 通讯作者: Boisson-Dupuis S

Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies.

• DOI: 10.1016/j.jaci.2015.05.036
• 发表时间: 2015-10
• 期刊: The Journal of allergy and clinical immunology
• 作者: Ma CS;Wong N;Rao G;Avery DT;Torpy J;Hambridge T;Bustamante J;Okada S;Stoddard JL;Deenick EK;Pelham SJ;Payne K;Boisson-Dupuis S;Puel A;Kobayashi M;Arkwright PD;Kilic SS;El Baghdadi J;Nonoyama S;Minegishi Y;Mahdaviani SA;Mansouri D;Bousfiha A;Blincoe AK;French MA;Hsu P;Campbell DE;Stormon MO;Wong M;Adelstein S;Smart JM;Fulcher DA;Cook MC;Phan TG;Stepensky P;Boztug K;Kansu A;İkincioğullari A;Baumann U;Beier R;Roscioli T;Ziegler JB;Gray P;Picard C;Grimbacher B;Warnatz K;Holland SM;Casanova JL;Uzel G;Tangye SG
• 通讯作者: Tangye SG

Temporal Lineage Tracing of Aire-Expressing Cells Reveals a Requirement for Aire in Their Maturation Program

• DOI: 10.4049/jimmunol.1302786
• 发表时间: 2014-03-15
• 期刊: JOURNAL OF IMMUNOLOGY
• 影响因子: 4.4
• 作者: Nishikawa, Yumiko;Nishijima, Hitoshi;Matsumoto, Mitsuru
• 通讯作者: Matsumoto, Mitsuru

Comel-Netherton症候群

康梅尔-内瑟顿综合征

• 发表时间: 2015
• 期刊: 日本臨床 免疫症候群III
• 作者: Rupani H;Lau L;Ono J;Barber C;Elliot S;Brown T;Kurukulaaratchy R;Chauhan A;Izuhara K;中里雅光;峯岸克行
• 通讯作者: 峯岸克行

PGM3欠損症

PGM3 缺乏症

• 发表时间: 2015
• 期刊: 日本臨床 免疫症候群III
• 作者: Goto K.;Takemura G.;Takahashi T.;Okada H.;Kanamori H.;Kawamura I.;Watanabe T.;Morishita K.;Tsujimoto A.;Miyazaki N.;Ushikoshi H.;Kawasaki M.;Mikami A.;Kosai K.;Minatoguchi S.;峯岸克行
• 通讯作者: 峯岸克行