METHODS TO DETECT HIV AND RELATED RETROVIRUSES

自从人类免疫缺陷病毒(HIV)被发现为 艾滋病的病原体，针对 两种疾病的流行病学、预防、发病机制和适当治疗 潜在的疾病和后遗症已经加剧。然而，有几个 这项工作的各个方面由于缺乏相对简单、 快速定量检测病毒或其成分的方法 实验系统或临床材料中的抗原。成功者 改进方法的发展将加强对以下各方面的研究 整个科学界都有艾滋病，但对工作特别有利 他还表示，艾滋病防治战略计划将用于疫苗和治疗方案的开发。 缺乏快速、定量的分析，再加上目前缺乏 用于感染的动物模型系统使治疗方法的发展 而疫苗尤其困难。这份合同的目的是 确保更简单、更快速、更定量的方法检测 艾滋病毒和相关逆转录病毒将在最快的时间内开发出来 举止。这项研究的最终产品(S)应该允许准备好 临床艾滋病毒及相关逆转录病毒的检测， 动物和实验室标本。

Since the discovery of the human immunodeficiency virus (HIV) as the etiological agent of AIDS, research efforts directed toward the epidemiology, prevention, pathogenesis, and adequate treatment of both the underlying disease and is sequelae have been intensified. However, several aspects of the work have been hampered by the lack of relatively simple, rapid and quantitative methods for detecting the virus or its constituent antigens in experimental systems or clinical materials. The successful development of improved methods would enhance research on all aspects of AIDS throughout the scientific community but would especially benefit work of the AIDSP toward the development of vaccines and therapeutic regimens. The lack of rapid, quantitative assays coupled with the present paucity of animal model systems for the infection makes the development of therapies and vaccines particularly difficult. The objective of this contract is to assure that simpler, faster, and quantitative methods for the detection of HIV and related retroviruses will be developed in the most expeditious manner. The end product(s) of this research should permit the ready detection and measurement of HIV and related retroviruses in clinical, animal and laboratory specimens.