THE MATERNAL GUT MICROBIOTA DRIVES FOETAL THYMIC T CELL DEVELOPMENT
母体肠道微生物群驱动胎儿胸腺 T 细胞发育
基本信息
- 批准号:DP210102943
- 负责人:
- 金额:$ 31.78万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Discovery Projects
- 财政年份:2021
- 资助国家:澳大利亚
- 起止时间:2021-01-01 至 2024-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This project aims to investigate the role of maternal gut microbiota on foetal immune development, revealing the interaction of gut microbiota-host immunity at the early stages of new life. Significantly, the research will examine the time window when microbiota by-products from the mother reach the foetus and affect the development of immunity. Maternal by-products will be identified using cutting-edge methods to unravel the complex systems interactions in the developmental process. Outcomes include new fundamental knowledge about maternal gut microbiota composition and its relationship to the growing foetus, with benefits in informing pregnant women about their lifestyle choices, particularly their dietary habits, during pregnancy.
本项目旨在研究母体肠道菌群对胎儿免疫发育的影响,揭示新生生命早期肠道菌群-宿主免疫的相互作用。值得注意的是,这项研究将检验母体微生物副产物到达胎儿并影响免疫发育的时间窗口。母体副产品将确定使用尖端的方法来解开复杂的系统相互作用在发展过程中。结果包括关于母体肠道微生物群组成及其与胎儿生长关系的新基础知识,有助于告知孕妇怀孕期间的生活方式选择,特别是饮食习惯。
项目成果
期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Prof Ralph Nanan其他文献
Prof Ralph Nanan的其他文献
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