Diamond electrodes for bimodal cellular control

用于双峰细胞控制的金刚石电极

• 批准号: DP210102750
• 负责人: Prof Steven Prawer
• 金额: $ 30.86万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-05-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210102750
• 关键词: Diamond; electrodes; bimodal; cellular; control

The objective of the work proposed here is to develop a new tool for investigating intercellular communication. Currently, techniques for probing cellular functions are either well-suited to controlling a limited number of individual inputs or a large number of complete cells. This projects aims to address these limitations by utilising cutting edge fabrication techniques to create an optically controlled nanoscale array of diamond electrodes, capable of modulating a large number of single cellular inputs with precision. This technology will allow researchers to manipulate cellular processes with more control than ever before, potentially gaining insights useful for understanding brain function, memory formation, or cell death.

这里提出的工作的目标是开发一种新的工具，用于调查细胞间通信。目前，用于探测细胞功能的技术非常适合于控制有限数量的个体输入或大量的完整细胞。该项目旨在通过利用先进的制造技术来创建一个光学控制的纳米级金刚石电极阵列来解决这些限制，该阵列能够精确地调节大量的单细胞输入。这项技术将使研究人员能够比以往任何时候都更好地控制细胞过程，从而可能获得对理解大脑功能、记忆形成或细胞死亡有用的见解。