Brown University and University of the Philippines Training Program for the Prevention of HIV in Vulnerable Populations

摘要 菲律宾目前正在经历世界上增长最快的艾滋病毒流行之一。艾滋病病毒 菲律宾的流行率在2006年之前一直保持在低水平和休眠状态，但在2007年，疫情发生了转变 发生的情况使得艾滋病毒传播主要归因于男性同性行为。在此之后 转折点艾滋病毒疫情迅速扩大，据估计，报告病例比 2008-2013年，90%的新监测病例集中在男男性行为者(MSM)和 变性女性。菲律宾的卫生服务目前还不能充分满足艾滋病毒预防的需要， 检测或治疗该国最脆弱的人群，如男男性接触者和变性人 女人。缺乏艾滋病毒服务的同时，菲律宾开展高质量服务的能力有限 关于艾滋病毒预防/治疗的研究，并针对弱势人群设计有效的干预措施，例如 男男性接触者和变性女性。菲律宾马尼拉大学(UPM)是首屈一指的健康科学 ，并在战略上处于领先地位，成为艾滋病毒研究的领先者 弱势群体。然而，芬欧汇理目前缺乏一支规模可观的研究科学家队伍，他们拥有 对男男性接触者和变性妇女进行尖端艾滋病毒预防/治疗研究的培训；以及 缺乏必要的课程和课程来培养下一代艾滋病毒研究科学家 菲律宾。拟议的D43培训方案将通过建立伙伴关系来回应这一需求 在芬欧汇理和布朗大学之间。该培训计划建立在之前成功的合作伙伴关系基础上，并 芬欧汇理与布朗的合作：福格蒂艾滋病国际培训研究计划(AITRP)， 它在菲律宾培训了21名艾滋病毒科学家，内容涉及艾滋病毒感染的临床方面、艾滋病毒基础流行病学、 和行为预防咨询。该计划将进一步扩大研究和教育/课程 通过实现以下具体目标，提高芬阵的能力：(1)利用长期培训扩大队伍 研究科学家专注于对MSM和变性人妇女进行艾滋病毒干预研究 菲律宾(5年以上2名博士生和5名硕士生)；(2)促进芬欧汇理的修订和扩展 艾滋病毒对弱势人群的干预课程；(3)设立年度研究讲习班 关于艾滋病毒对弱势人群的干预，总部设在芬欧汇理，以传播研究结果， 建立专业网络，并动员新的研究项目。这项计划提案代表了一项长期的 两所合作大学的研究人员之间的承诺和合作，以及该项目的规划 通过咨询临床专业人员、政府和非政府艾滋病毒服务机构而得知 供应商，以及菲律宾的利益攸关方。培训计划与Trans-NIH中规定的优先事项一致 关于艾滋病毒/艾滋病的战略计划，改善研究、培训能力和发展的基础设施 目前关于艾滋病毒在菲律宾迅速增长的流行病的科学知识。

ABSTRACT The Philippines is currently experiencing one of the fastest growing HIV epidemics in the world. HIV prevalence in the Philippines had initially remained low and dormant until 2006, but in 2007 an epidemic shift occurred such that HIV transmission became attributed primarily to male same-sex behavior. Following this turning point the HIV epidemic has expanded rapidly, with an estimated 812% increase in reported cases from 2008-2013 and 90% of new surveillance cases concentrated in men who have sex with men (MSM) and transgender women. Health services in the Philippines currently do not adequately meet the HIV prevention, testing, or treatment needs of the country’s most vulnerable populations such as MSM and transgender women. This lack of HIV services parallels the limited capacity in the Philippines to conduct high-quality research on HIV prevention/treatment and to design effective interventions with vulnerable populations such as MSM and transgender women. The University of the Philippines Manila (UPM) is the premier health sciences research university in the Philippines, and is strategically positioned to be a leader in HIV research with vulnerable populations. However, UPM currently lacks a sizable cadre of research scientists who have the training to conduct cutting-edge HIV prevention/treatment research with MSM and transgender women, and lacks necessary coursework and curriculum to train the next generation of HIV research scientists in the Philippines. The proposed D43 training program will respond to this need by establishing a partnership between UPM and Brown University. This training program builds on a previous successful partnership and collaboration between UPM and Brown: the Fogarty AIDS International Training Research Program (AITRP), which trained 21 HIV scientists in the Philippines on clinical aspects of HIV infection, basic HIV epidemiology, and behavioral prevention counseling. The program will further expand research and educational/curricular capacity at UPM by accomplishing the following Specific Aims: (i) Use long-term training to expand the cohort of research scientists focusing on HIV intervention research with MSM and transgender women in the Philippines (2 PhD and 5 Master’s students over 5 years); (ii) Facilitate revision and expansion of UPM curriculum on HIV interventions with vulnerable populations; (iii) Establish an annual Workshop for Research on HIV Interventions with Vulnerable Populations, based at UPM, for dissemination of research findings, professional networking, and mobilizing new research projects. This program proposal represents a long-term commitment and collaboration between researchers at both partner Universities, and planning of this program was informed by consultation with clinical professionals, governmental and non-governmental HIV service providers, and stakeholders in the Philippines. The training plan aligns with priorities set forth in the Trans-NIH strategic plan on HIV/AIDS, by improving the infrastructure for research training capacity and growth of the current body of scientific knowledge on HIV in this rapidly growing epidemic in the Philippines.