R25EB023856 Supplement LeeYM P0546225

项目摘要 加州大学旧金山分校弗朗西斯科外科系与生物工程系合作， 治疗科学，建议在临床领域建立跨学科的R25研究教育计划 以及为外科住院医生提供的“生物设备创新”。外科医生拥有广泛的知识， 解剖学，非常熟悉患者的需求和当前技术的局限性， 具有较强的解决问题的能力，因为需要不断地即兴解决问题， 手术室然而，NIH资助的外科医生调查人员的水平下降， 手术培训计划的变化和创新方法的引入，以吸引更多的 研究中的外科医生设备创新越来越被认为是一个研究领域， 外科医生可以做出重大的创造性贡献，深刻地影响病人的护理。设计用于外科手术 居民感兴趣的职业作为临床创新者，拟议的计划将提供动手研究 在他们的两个专门的研究年居民的经验，与杰出的教师一起工作 来自外科、生物工程、放射学和其他相关临床学科的创新者， 为未满足的临床需求提供基于设备的新型解决方案。在此过程中，参与者将制定 必要的生物工程研究技能，医疗产品开发过程的知识，和导师 关系，以帮助启动自己的研究生涯，成功地竞争赠款资金， 作为独立的外科医生-科学家成功地参与器械创新。领导团队拥有多... 一年的合作历史，将生物工程的进步转化为创新的新治疗模式 通过成功的项目，如FDA赞助的UCSF儿科项目， 设备联盟和UCSF的手术创新计划。该计划的许多关键要素是 已经到位，包括与UCSF-加州大学伯克利分校生物工程联合研究生组的联系，UCB- UCSF转化医学硕士课程，UCSF斯坦福大学卓越中心监管 科学与创新（CERSI），以及支持UCSF设备创新的强大基础设施。培训 该计划得到了优秀的导师团队的支持，其中包括国际知名的教师，他们 设备创新的成就。

Project Summary The UC San Francisco Department of Surgery, in collaboration with the Department of Bioengineering and Therapeutic Sciences, proposes to establish an interdisciplinary R25 research education program in clinical and translational “Biodevice Innovation” for surgical residents. Surgeons possess extensive knowledge of anatomy, are intimately familiar with the needs of their patients and the limitations of current technology, and possess strong problem solving abilities developed out of the necessity to constantly improvise solutions in the operating room. However, the declining levels of NIH-funded surgeon-investigators necessitates structural changes in surgical training programs and the introduction of innovative approaches in order to engage more surgeons in research. Device innovation is becoming increasingly recognized as a research area in which surgeons can make significant creative contributions that profoundly impact patient care. Designed for surgical residents interested in careers as clinician-innovators, the proposed program would provide hands-on research experiences for residents during their two dedicated research years to work alongside prominent faculty innovators from Surgery, Bioengineering, Radiology, and other relevant clinical disciplines to develop and translate novel device-based solutions for unmet clinical needs. In the process, participants will develop the requisite bioengineering research skills, knowledge of the medical product development process, and mentor relationships to help launch their own research careers, successfully compete for grant funding, and successfully engage in device innovation as independent surgeon-scientists. The leadership team has a multi- year history of collaboration translating advances in bioengineering into innovative new treatment paradigms and breakthroughs in clinical care through successful programs such as the FDA-sponsored UCSF Pediatric Device Consortium and UCSF's Surgical Innovations Initiative. Many of the key elements of the program are already in place, including ties to the UCSF-UC Berkeley Joint Graduate Group in Bioengineering, the UCB- UCSF Master of Translational Medicine Program, the UCSF-Stanford Center of Excellence in Regulatory Science & Innovation (CERSI), and a robust infrastructure supporting device innovation at UCSF. The training program is supported by an outstanding mentorship team including faculty internationally renowned for their achievements in device innovation.