BoostOne

项目总结 阿片类药物使用障碍(OUD)患者面临着短期和长期的健康和 富有成效的决策。复苏，特别是在垫子的背景下(但也是更普遍的)，是深刻的 受阶段性/心理渴望的影响，长期决策能力受损。目前的渴望- 在常见的环境/社会背景下，回避工具的可用性和实用性有限。在……里面 此外，大多数内省或自我控制的改进策略(正念、CBT)不适合 在脆弱时刻接受治疗，而临床咨询或同伴支持则受到规模/访问的影响 限制。对此，我们提出了一种现场可部署的(移动智能手机)、自动化的急性干预措施 OUD中的渴望，同时解决了长期冲动决定的神经生物学驱动因素- 制作。创新(BoostONE)包括一个即时渴望管理系统(Boost-C)和 冲动性缓解(Boost-I)，并包括执行功能的心理测量框架 结果跟踪。个人使用MAT的预期影响将在可行性研究中进行评估 经过验证的包。我们预计此第一阶段SBIR将为部署BoostONE奠定基础 积极治疗环境和基础技术框架的更广泛扩展。

PROJECT SUMMARY Individuals with opioid user disorder (OUD) face both short-term and long-horizon challenges to healthy and productive decision-making. Recovery, particularly in the setting of MAT (but also more generally), is deeply affected by phasic/psychological cravings and impaired long-horizon decision-making. Current cravings- avoidance tools suffer from limited usability and restricted utility in common environmental/social contexts. In addition, the majority of introspective or self-control improvement strategies (mindfulness, CBT) are unsuited for uptake during moments of vulnerability, while clinical counseling or peer support suffer from scale/access limitations. In response, we propose a field-deployable (mobile smartphone), automated intervention for acute cravings in OUD which simultaneously addresses neurobiological drivers of long-term impulsive decision- making. The innovation (“BoostONE”) comprises a system for just-in-time cravings management (Boost-C) and impulsivity mitigation (Boost-I) and includes a framework for psychometric measurement of executive function for outcomes tracking. Predicted effects of usage by individuals in MAT will be evaluated in a feasibility study of the validated package. We anticipate this Phase I SBIR will provide the foundation for deployment of BoostONE in active treatment settings and for broader extensions of the underlying technology framework.