CBEC-KEMRI BIOETHICS TRAINING INITIATIVE

摘要 低收入和中等收入国家的人类受试者研究呈指数增长 (LMIC在过去的二十年里， 训练有素的生物伦理学家，导致研究监管的关键空白。肯尼亚有22个认证 机构研究伦理委员会（IREC），每个委员会有10-15名成员。为了解决这个问题， 肯尼亚医学研究所与生物医学中心合作， 巴基斯坦卡拉奇的生物伦理和文化中心（CBEC）努力加强生物伦理方面的能力 通过建立CBEC-KEMRI生物伦理培训中心， 倡议（CK-BTI），提供生物伦理学硕士（MBE），研究生文凭（PGD）和 生物伦理学证书课程。具体而言，这一合作培训举措将培训核心 为肯尼亚培训核心教员：为一个国家的生物伦理学研究建立初步能力， 可持续发展计划，（目标2）建立一个创新和合作的生物伦理学课程， 肯尼亚（目标3）在当地提供伦理学研究生文凭和硕士学位 （目标4）通过提供证书课程，迅速建立区域环境委员会的审查能力， 设计一个实习，其中包括如何管理REC的实践经验 为肯尼亚和巴基斯坦的区域环境委员会成员提供秘书处服务。根据CK-BTI，共有350名 肯尼亚参加者将接受以下培训：8名MBE学生，22名PGD学生和320名 证书参与者。此外，30名巴基斯坦学者，包括10名MBE候选人和20名 CBEC相关参与者将在KEMRI进行实习，以丰富他们的实践经验。 利用文化多样性的研究环境理解伦理问题，以及 提高他们在运行忙碌IRB办公室中的动手能力。CK-BTI将提供三个独特的 包括远程学习部分的单元培训 适合不同的申请人基础，在KEMRI科学和道德的实践经验 审查单位（SERU）旨在影响委员会和IRB秘书处的职能，以及 最后，提供丰富的跨文化生物伦理学经验。该倡议将针对参与者 来自医学研究领域、卫生保健专业人员、区域经济共同体成员和来自 不同的背景，这将确保广泛的高等教育机构， 肯尼亚和巴基斯坦的区域经济共同体受益于培训。我们计划开发一个临界质量的 训练有素的专业人员、学者、研究科学家和其他卫生专业人员， 肯尼亚和巴基斯坦，对伦理考虑、概念和 和社会、生物医学、临床和公共卫生研究领域的应用，世卫组织将 影响他们的机构，并成为各自国家生物伦理学的领导者。

Abstract An exponential increase in human subjects research in low and middle income countries (LMIC's) in the last two decades has not been accompanied by a commensurate increase in trained bioethicists, resulting in a critical gap for research regulation. Kenya has 22 accredited Institutional Research Ethics Committees (IREC) each with 10-15 members. To address this, the Kenya Medical Research Institute (KEMRI) in partnership with the Centre for Biomedical Ethics and Culture (CBEC) in Karachi, Pakistan, seek to strengthen capacity for bioethics training in the two countries through the establishment of the CBEC-KEMRI Bioethics Training Initiative (CK-BTI), that offers a Masters in Bioethics (MBE), Post- Graduate Diploma (PGD) and Certificate Courses in Bioethics. Specifically, this collaborative training initiative will train core faculty for Kenya (Aim 1), To train core faculty for Kenya: building initial bioethics capacity for a sustainable program, (Aim 2) To build an innovative and collaborative curriculum in bioethics for Kenya (Aim 3) To offer locally available Post Graduate Diploma and Masters in Ethics degree courses (Aim 4) To rapidly build capacity for review for REC by offering certificate courses and to design a practicum which includes hands on experience on how to manage an REC secretariat for REC members for both Kenya and Pakistan. Under the CK-BTI, a total of 350 Kenyan participants will be trained as follows: 8 MBE students, 22 PGD students and 320 certificate participants. In addition, 30 Pakistani scholars comprising 10 MBE candidates and 20 CBEC-linked participants will undertake a practicum at KEMRI to enrich their practical understanding of ethical issues using a culturally-diverse research environment, as well as enhance their hands-on skills in the running of a busy IRB office. CK-BTI will offer three unique and innovative features: modular training which encompasses a distance learning component suitable for a diverse applicant base, practical experience at the KEMRI Scientific and Ethics Review unit (SERU) designed to impact the function of committees and IRB secretariats, and lastly to provide a rich cross-cultural bioethics experience. This initiative will target participants from the medical research field, health care professionals, members of RECs and trainees from diverse backgrounds, which will ensure that a wide range of Institutions of higher learning, and RECs in Kenya and Pakistan benefit from the training. We plan to develop a critical mass of well-trained professionals, academics, research scientists, and other health professionals in Kenya and Pakistan with in-depth and practical knowledge of ethical considerations, concepts and applications in social, biomedical, clinical and public health research areas and who will impact their institutions and be leaders of bioethics in their respective countries.