Laboratory Flexible Funding Model (LFFM) (U19) Clinical Trials Not Allowed

实验室灵活资助模式 (LFFM) (U19) 不允许进行临床试验

• 批准号: 10172238
• 负责人: Jordan Polaskey
• 金额: $ 96万
• 依托单位: MICHIGAN STATE DEPT OF AGRICULTURE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10172238
• 关键词: Laboratory; Flexible; Funding; Model; LFFM

PROJECT SUMMARY (OVERALL): The Michigan Department of Agriculture and Rural Development (MDARD) intends use this opportunity to support activities to meet regulatory requirements, and improve its efficacy, accuracy, and defensibility on a continuous basis and to maintain and enhance our current level of services with our federal, state, and local partners. This funding opportunity also allows for the risk-based development of metrics to base objectives upon, allowing MDARD to better forecast emerging issues and hazard. This funding will allow MDARD to work with our regulatory partners to develop plans and processes to facilitate the increase sample volumes across our human and animal food microbiology and chemistry sections to work with our regulatory partners in the process of increasing the types of analysis across the two section by allowing for new advanced technologies and methodologies to be explored such as Whole Genome Sequencing, allergens, food adulteration, toxic elements, and economic fraud. The lab will maintain its ISO 17025 accreditation providing confidence and defensibility in the labs results. MDARD will continue to work with the Emergency Rapids Response Team and the MDARD Food and Dairy Division and FDA to build a more robust and effective food defense program. The Michigan Department of Agriculture and Rural Development (MDARD) Chemistry Laboratory intends to continue its basic scope which of testing for human and animal food; mycotoxins, veterinary drugs, nutrient and heavy metals, crude fat content, crude fiber content, and protein (Nitrogen) content, acid detergent fiber, neutral detergent fiber, filth, fish speciation, histamine, cannabidiol potency in food products and foreign materials in feed products whilst increasing sample volumes and participating in any food defense outbreaks, investigations, exercises, and trainings, Chemistry will participate in Track 4 building the section's allergen testing program. The Michigan Department of Agriculture and Rural Development (MDARD) Microbiology Laboratory emphasizes food safety for human food through surveillance testing for foodborne pathogens. Testing is performed using validated and verified test methods. The lab routinely tests samples for Salmonella, Listeria monocytogenes and pathogenic E. coli (Shiga-toxin producing E. coli, or STEC) Surveillance manufactured food samples and fresh produce samples are tested for the presence of the foodborne pathogens. Samples found to be contaminated with foodborne pathogens will be reported to the Regulatory Division and FDA for possible regulatory action. The Microbiology Laboratory has recently committed to a multi-lab validation (MLV) through test tattoo ink for Mycobacterium spp.

项目概要（总体）： 密歇根州农业和农村发展部（MDARD）打算利用这个机会， 支持满足监管要求的活动，并提高其有效性、准确性和 持续的防御能力，并保持和提高我们目前的服务水平， 联邦州和地方合作伙伴。 这种融资机会还允许基于风险制定指标，以实现目标， 使MDARD能够更好地预测新出现的问题和危险。这笔资金将使MDARD能够 与我们的监管合作伙伴一起制定计划和流程，以促进样本量的增加 在我们的人类和动物食品微生物学和化学部门与我们的监管部门合作 在增加这两个部分的分析类型的过程中， 先进的技术和方法有待探索，如全基因组测序， 过敏原、食品掺假、有毒元素和经济欺诈。实验室将保持其ISO 17025 认证提供了实验室结果的信心和辩护。MDARD将继续工作 与紧急急流响应小组、MDARD食品和乳制品部门以及FDA合作， 更强大和有效的粮食防御计划。 密歇根州农业和农村发展部（MDARD）化学实验室 打算继续其基本范围，即测试人类和动物食品;霉菌毒素，兽医 药物、营养和重金属、粗脂肪含量、粗纤维含量和蛋白质（氮）含量， 酸性洗涤纤维，中性洗涤纤维，污物，鱼类，组胺，大麻二酚 产品和饲料产品中的异物，同时增加样品量， 任何食品防御爆发，调查，演习和培训，化学将参加跟踪 4建立该部门的过敏原检测计划。 密歇根州农业和农村发展部（MDARD）微生物实验室 强调通过对食源性病原体的监测检测，确保人类食品的食品安全。测试是 使用经确认和验证的测试方法进行。实验室定期检测沙门氏菌样本， 单核细胞增生李斯特菌和致病性E. coli（产志贺毒素E.大肠杆菌，或STEC）监测 制造的食物样本和新鲜农产品样本进行测试，以确定是否存在食源性 病原体如发现样本受食源性病原体污染， 监管部门和FDA可能采取的监管行动。微生物实验室最近 致力于通过测试纹身墨水进行多实验室确认（MLV），以检测分枝杆菌属。