Laboratory Flexible Funding Model (LFFM) (U19) Clinical Trials Not Allowed

项目摘要（总体）： 密歇根州农业和农村发展部 (MDARD) 打算利用这个机会 支持满足监管要求的活动，并提高其有效性、准确性和 持续防御，并通过我们的服务维持和提高我们当前的服务水平 联邦、州和地方合作伙伴。 这一融资机会还允许基于风险的指标开发，以实现目标， 使 MDARD 能够更好地预测新出现的问题和危险。这笔资金将使 MDARD 发挥作用 与我们的监管合作伙伴一起制定计划和流程，以促进增加样本量 我们的人类和动物食品微生物学和化学部门与我们的监管部门合作 合作伙伴正在通过允许新的方法来增加跨两个部分的分析类型 有待探索的先进技术和方法，例如全基因组测序、 过敏原、食品掺假、有毒元素和经济欺诈。该实验室将维持其 ISO 17025 认证为实验室结果提供信心和辩护性。 MDARD 将继续发挥作用 与紧急快速反应小组、MDARD 食品和乳制品部门以及 FDA 合作，建立一个 更稳健、更有效的食品防御计划。 密歇根州农业和农村发展部 (MDARD) 化学实验室 打算继续其人类和动物食品测试的基本范围；霉菌毒素，兽用 药物、营养素及重金属、粗脂肪含量、粗纤维含量、蛋白质（氮）含量、 酸性洗涤纤维、中性洗涤纤维、污物、鱼类形态、组胺、食品中的大麻二酚效力 产品和饲料产品中的异物，同时增加样品量并参与 任何食品防御爆发、调查、演习和培训，化学将参加跟踪 4 建立该部门的过敏原检测计划。 密歇根州农业和农村发展部 (MDARD) 微生物实验室 通过对食源性病原体进行监测检测来强调人类食品的食品安全。测试是 使用经过验证和验证的测试方法进行。该实验室定期检测样品中的沙门氏菌， 单核细胞增多性李斯特菌和致病性大肠杆菌（产志贺毒素大肠杆菌，或 STEC）监测 测试制造食品样品和新鲜农产品样品中是否存在食源性疾病 病原体。发现被食源性病原体污染的样品将报告给卫生部门 监管部门和 FDA 采取可能的监管行动。近期，微生物实验室 致力于通过测试纹身墨水对分枝杆菌进行多实验室验证 (MLV)。

PROJECT SUMMARY (OVERALL): The Michigan Department of Agriculture and Rural Development (MDARD) intends use this opportunity to support activities to meet regulatory requirements, and improve its efficacy, accuracy, and defensibility on a continuous basis and to maintain and enhance our current level of services with our federal, state, and local partners. This funding opportunity also allows for the risk-based development of metrics to base objectives upon, allowing MDARD to better forecast emerging issues and hazard. This funding will allow MDARD to work with our regulatory partners to develop plans and processes to facilitate the increase sample volumes across our human and animal food microbiology and chemistry sections to work with our regulatory partners in the process of increasing the types of analysis across the two section by allowing for new advanced technologies and methodologies to be explored such as Whole Genome Sequencing, allergens, food adulteration, toxic elements, and economic fraud. The lab will maintain its ISO 17025 accreditation providing confidence and defensibility in the labs results. MDARD will continue to work with the Emergency Rapids Response Team and the MDARD Food and Dairy Division and FDA to build a more robust and effective food defense program. The Michigan Department of Agriculture and Rural Development (MDARD) Chemistry Laboratory intends to continue its basic scope which of testing for human and animal food; mycotoxins, veterinary drugs, nutrient and heavy metals, crude fat content, crude fiber content, and protein (Nitrogen) content, acid detergent fiber, neutral detergent fiber, filth, fish speciation, histamine, cannabidiol potency in food products and foreign materials in feed products whilst increasing sample volumes and participating in any food defense outbreaks, investigations, exercises, and trainings, Chemistry will participate in Track 4 building the section's allergen testing program. The Michigan Department of Agriculture and Rural Development (MDARD) Microbiology Laboratory emphasizes food safety for human food through surveillance testing for foodborne pathogens. Testing is performed using validated and verified test methods. The lab routinely tests samples for Salmonella, Listeria monocytogenes and pathogenic E. coli (Shiga-toxin producing E. coli, or STEC) Surveillance manufactured food samples and fresh produce samples are tested for the presence of the foodborne pathogens. Samples found to be contaminated with foodborne pathogens will be reported to the Regulatory Division and FDA for possible regulatory action. The Microbiology Laboratory has recently committed to a multi-lab validation (MLV) through test tattoo ink for Mycobacterium spp.