Administrative Core

行政核心

• 批准号: 10171103
• 负责人: Elsa R Flores
• 金额: $ 10.37万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-25 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10171103
• 关键词: Achievement; Administrator; Area; Biological; Budgets; Cancer Center; Collaborations; Communication; Communities; Conceptions; Data; Data Analyses; Data Science; Data Science Core; Databases; Development; Disease; Doctor of Philosophy; Ensure; Experimental Designs; Fostering; Goals; Institutional Policy; Laboratories; Leadership; Logistics; Malignant Neoplasms; Malignant neoplasm of lung; Metabolic; Metabolism; Methods; Modeling; Molecular; National Cancer Institute; Phenotype; Preparation; Procedures; Program Research Project Grants; Progress Reports; Publications; Records; Regulation; Reproducibility; Resource Sharing; Resources; Role; Sampling; Scientist; Services; TimeLine; Training; United States National Institutes of Health; Work; animal imaging; cancer subtypes; comparative; data repository; data sharing; data submission; experience; experimental analysis; experimental study; meetings; member; mouse model; operation; programs; quality assurance; success; synergism; tumor metabolism

CORE 1 PROJECT SUMMARY ADMINISTRATIVE CORE The Administrative Core serves as the central node for all Projects and Cores of the Program Project Grant (PPG) with the overarching goal of providing resources and facilitating interactions between the laboratories involved. To accomplish this goal, two PhD level scientists have been appointed to distinct and complementary roles within the Administrative Core. The PPG Administrative Director will specialize in providing administrative, organizational, and communication support in order to facilitate the completion of program project goals (Aim 1). To accomplish this aim, the PPG Administrative Director will organize regular meetings of the program project group, plan an annual retreat including the Internal and External Advisory Boards, and oversee the fiscal operations of all projects and cores to ensure compliance with the proposed budgets and timelines. The PPG Project Management Director will be responsible for ensuring robust integration of project and core activities with the highest level of scientific rigor and reproducibility of data (Aim 2). This aim will include the development of a database of standard operating procedures (SOPs) for both experimental design and data analysis in order to optimize the reproducibility of experiments across disease platforms and program project laboratories. Additionally, the PPG Project Management Director will implement clear experimental pipelines to facilitate the transition of samples and data across multiple program project and/or institutional cores. Finally, the members of the Administrative Core will work together with Core #4 (Data Science Core) to support the internal and external sharing of program project generated resources (Aim 3). For the internal sharing of data, Core #1 and Core #4 will maintain the Lung Cancer Data Repository (LCDR) which will allow comparative analyses across projects, species, and lung cancer subtypes. As the point of contact for both internal and external sharing of resources, the Administrative Core is essential for fostering synergy among the program project members and for ensuring the long-term success of the PPG team.

核心1项目总结 行政核心 行政核心是所有项目和项目补助金核心的中心节点 (PPG)其总体目标是提供资源并促进实验室之间的互动 涉案为了实现这一目标，两名博士水平的科学家被任命为不同的和互补的 在行政核心中的作用。PPG行政总监将专门提供行政， 组织和沟通支持，以促进完成计划项目目标（目标1）。 为了实现这一目标，PPG行政总监将定期组织项目会议 小组，计划年度务虚会，包括内部和外部咨询委员会，并监督财政 所有项目和核心的运作，以确保遵守拟议预算和时间表。的PPG 项目管理主任将负责确保项目和核心活动与 最高水平的科学严谨性和数据再现性（目标2）。这一目标将包括发展 用于实验设计和数据分析的标准操作程序（SOP）数据库， 优化跨疾病平台和项目实验室的实验重现性。 此外，PPG项目管理总监将实施明确的实验管道，以促进 样本和数据在多个程序项目和/或机构核心之间的转换。最后，成员 管理核心的核心将与核心#4（数据科学核心）合作，以支持内部和 外部共享计划项目产生的资源（目标3）。对于内部数据共享，核心#1和 核心#4将维护肺癌数据库（LCDR），该库将允许对 项目、物种和肺癌亚型。作为内部和外部共享的联系点， 资源，行政核心对于促进计划项目成员之间的协同作用至关重要， 确保PPG团队的长期成功。