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中文摘要
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总结 核心A是行政核心设施,负责整体行政工作,以支援研究目的 和目标的计划,并进一步负责满足所有计划的行政要求 所涉及的多个机构。核心A将提供完成以下工作所必需的服务: 研究目标解决整个计划的中心假设:蛋白质糖基化和糖蛋白 重塑改变凝血病和脓毒症的炎症。核心A提供行政职能, 是所有项目、核心设施和项目资助人员所需要的。核心A将成为 项目参与者之间的项目沟通,包括项目领导人、核心领导人、顾问 董事会成员、合作者和顾问以及实验室和研究人员。整体 核心A的行政目标是建立和维持基本的方案行政职能, 最有效和最佳的方式。此外,核心A将继续建立和维护 根据需要与多个办公室和工作人员进行有效的部门间和机构间沟通, 履行所需的行政职责。核心A行政设施将保留相关记录, 计划活动,以满足申请中详细说明的行政要求。行政 核心A的功能包括维持有效的办公基础设施, 通信、监测项目和核心支出、协助 项目人员、相关项目会议和进度报告的执行和记录保存, 编写和维护项目人员通信列表,协助项目人员 关于计划出版物和组成以及计划报告的提交,会议的组织 项目调查人员、工作人员和顾问委员会成员的名单,以及项目的组织和执行情况 人员异地旅行,包括年度计划务虚会。核心A将进一步开展工作, 项目人员作为联络人与圣巴巴拉平房医院的医生和研究办公室工作人员, 促进通信和文件传输,使人类受试者的认证能够与 内部审查委员会认证,以支持该计划。核心A的结构和组织 包括一名核心领导和一名项目助理,他们将共同提供行政职能, 支持方案项目和核心人员及活动。
英文摘要
SUMMARY Core A is the administrative core facility responsible for overall administration in support of the research aims and goals of the program, and is further responsible for meeting all programmatic administrative requirements of the multiple institutions involved. Core A will provide services that are essential for the completion of research goals addressing the central hypothesis of the overall program: Protein glycosylation and glycoprotein remodeling alter the coagulopathy and inflammation of sepsis. Core A provides administrative functions that are needed by all of the projects, core facilities, and program-funded personnel. Core A will be the nexus of programmatic communications among program participants including project leaders, core leaders, advisory board members, collaborators and consultants, and laboratory and research personnel. The overall administrative goal of Core A is to establish and maintain essential programmatic administrative functions in the most efficient and optimal manner possible. In addition, Core A will continue to establish and maintain effective inter-departmental and inter-institutional communications with multiple offices and staff as needed to achieve the administrative duties required. The Core A administrative facility will maintain records of relevant program activities in fulfilling the administrative requirements as detailed in the application. The administrative functions of Core A include maintaining an effective office infrastructure with multiple routine modes of communication, monitoring project and core expenditures, assistance with orientation and administration of program personnel, execution and record keeping of relevant programmatic meetings and progress reports, composing and maintaining program personnel communication lists, assistance to program personnel regarding program publications and compositionand submission of program reporting, organization of meetings of program investigators, staff, and advisory board members, and organization and execution of program personnel off-site travel including annual program retreats. Core A will further operate in assistance with project personnel as a liaison with Santa Barbara Cottage Hospital physicians and research office staff in facilitating communications and documents transfers enabling accreditation regarding human subjects use with Internal Review Board certification in support of the program. The structure and organization of Core A includes a Core Leader and Program Assistant whom together will provide the administrative functions in support of program project and core personnel and activities.
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Regulation of Blood Glycoproteins by Lectin Receptors in Health and Disease
Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease
Protein Sialylation and De-Sialyation in Cell Surface Glycoprotein Homeostasis and Disease
Protein Glycosylation in the Coagulopathy and Inflammation of Sepsis
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