Wadsworth Center's Radiochemical Testing for Food Defense and Capability Development (Discipline C: Radiochemistry, Analytical Track 2: Radiochemistry Capability/Capacity Development, Expansion-Beta

沃兹沃斯中心的食品防御和能力开发放射化学测试（学科 C：放射化学、分析轨道 2：放射化学能力/能力开发、扩展-Beta

• 批准号: 10173142
• 负责人: Thomas Semkow
• 金额: $ 11.5万
• 依托单位: WADSWORTH CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10173142
• 关键词: Wadsworth; Center; Radiochemical; Testing; Food

PROJECT SUMMARY - Discipline C - Analytical Track 2 The principal goal of this project is to develop capability and capacity for radiological food protection from beta emitters, both nationwide and within New York State, including activities related to surveillance, emergency response, and method development. The proposed activities will be performed within the Nuclear Chemistry Laboratory section of Laboratory of Inorganic and Nuclear Chemistry at the Wadsworth Center, New York State Department of Health. Wadsworth Center, a comprehensive state public health laboratory, performs research and mandated testing in biomedical and environmental science. Its Division of Environmental Health Sciences is responsible for the analysis of environmental and food samples for toxic chemicals and radioactivity, as well as for laboratory activities in response to chemical and radiological threat-related incidents. The Wadsworth Center develops and validates laboratory methods for measuring chemical and nuclear threat agents and accredits clinical and environmental laboratories throughout New York State. Within Track 2: Radiochemistry Capability/Capacity Development, Expansion - Beta, in the Laboratory Flexible Funding Model, it is proposed to purchase a Hidex 300SL liquid scintillation counter (Hidex, Turku, Finland) with Alpha/Beta capability and Temperature Control, that will be used for activities related to surveillance, emergency response, and method development. In Track 1: Food Defense and Maintenance, we propose development of experimental and computational methods to screen and quantify Sr-89,90 and beta emitters in food for emergency response using Hidex 300SL, with significant benefits for FERN. In addition, we will use the Hidex 300SL to maintain capability and capacity for alpha/beta screening using the method developed at the US FDA’s Winchester Engineering and Analytical Center. We will establish appropriate counting programs for these methods on the Hidex instrument, perform calibrations specific to its proposed uses, train staff in its operation, as well as increase throughput for alpha/beta emitters in food. In addition, we propose maintenance of qualified and trained personnel for food radiochemistry and emergency, adherence to Wadsworth’s Quality Management System, as well as acquiring and calibration of equipment appropriate for radiological food defense. Furthermore, we will participate in/organize radiological exercises and Performance Tests for FERN, participate in FERN assignments, as well as attend Face-to-Face meetings and other conferences. Wadsworth Center’s Nuclear Chemistry Laboratory proposes development activities, such as method development and surge capacity development. The proposed methods involve Sr-89 and Sr-90 isotopic determination in food using liquid scintillation counting, determination of gross beta radioactivity in food using gas proportional counting as well as survey screening, in addition to quantitative approaches to beta radioactivity in food. We will also seek certification under ISO 17025 specifically for food analysis, to augment the laboratory certifications we already have.

项目总结-专业C -分析轨道2 该项目的主要目标是发展β辐射食品防护能力 在全国范围内和纽约州内，包括与监视、应急 响应和方法开发。拟议的活动将在核化学实验室内进行。 纽约沃兹沃斯中心无机与核化学实验室 州卫生部。沃兹沃斯中心是一个综合性的州公共卫生实验室，负责执行 生物医学和环境科学的研究和强制测试。环境卫生司 科学部负责分析环境和食品样本中的有毒化学物质， 以及应对化学和放射性威胁的实验室活动 事故。沃兹沃斯中心开发和验证测量化学品和 核威胁剂，并将其临床和环境实验室遍布纽约州。 轨道2内：放射化学能力/能力发展，扩展- Beta，在实验室灵活 供资模式，建议购买Hidex 300 SL液体闪烁计数器（Hidex，芬兰图尔库） 具有阿尔法/贝塔能力和温度控制，将用于与监视有关的活动， 应急响应和方法开发。在轨道1：食品防御和维护中，我们建议 开发实验和计算方法，以筛选和量化Sr-89，90和β发射体， 使用Hidex 300 SL的紧急响应食品，对FERN有显著的好处。此外，我们将使用 Hidex 300 SL使用开发的方法保持alpha/beta筛选的能力和容量， 美国FDA温彻斯特工程和分析中心我们将建立适当的计票程序 对于Hidex仪器上的这些方法，执行针对其拟议用途的校准， 操作，以及增加食品中α/β发射体的通量。 此外，我们建议维持合格和训练有素的食品放射化学人员， 遵守沃兹沃斯的质量管理体系，以及获取和校准 适用于放射性食品防护的设备。此外，我们将参加/组织放射性 FERN的练习和性能测试，参加FERN作业，以及参加面对面 会议和其他会议。沃兹沃斯中心的核化学实验室建议发展 方法开发和快速部署能力开发等活动。所提出的方法涉及Sr-89 用液体闪烁计数法测定食品中的锶和锶-90同位素， 除了定量测量外，还使用气体比例计数法和普查筛选法测量食品中的放射性 食物中的β放射性我们亦会特别就食物申请ISO 17025认证 分析，以增加我们已经拥有的实验室认证。