Scripps Center for Oceans and Human Health: advancing the science of marine contaminants and seafood security

斯克里普斯海洋与人类健康中心：推进海洋污染物和海鲜安全的科学

• 批准号: 2414798
• 负责人: Bradley Moore
• 金额: $ 432.3万
• 依托单位: University of California-San Diego Scripps Inst of Oceanography
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2024
• 资助国家: 美国
• 起止时间: 2024-03-01 至 2029-02-28
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2414798&HistoricalAwards=false
• 关键词: Scripps; Center; Oceans; Human; Health

The Scripps Center for Oceans and Human Health (SCOHH) is a five-year effort to advance the science and community engagement surrounding seafood pollutants, on a rapidly changing planet. The project brings together a multidisciplinary team of biomedical and oceanographic researchers with expertise in fish ecology, microbiology, marine chemistry, climate modeling, technology development, bioaccumulation, genomics, toxicology, and public health. The Center’s scientific goals and focus are guided by the needs of society, established through bidirectional community engagement, and led by a proven community engagement team. The proposed research program of SCOHH spans four main areas:1. Climate change impacts on the human intake of seafood micronutrients and contaminants. 2. The marine microbiome as a source for the synthesis, transformation, and distribution of seafood contaminants. 3. Mechanisms of bioaccumulation and developmental toxicity of seafood pollutants. 4. Bidirectional public engagement and literacy surrounding seafood risks and benefits.The outcomes of the SCOHH will inform policies, consumption guidelines, and individual decisions to lower risk and enhance greater benefits associated with seafood consumption. Internally, SCOHH will take deliberate measures to enhance equity, diversity, and inclusion in all aspects of its functioning, from the investigator team and graduate student/postdoctoral trainees to engagement with community partners. The Center is jointly supported by NSF’s Division of Ocean Sciences and by the National Institute for Environmental Health Sciences (NIEHS).The central scientific theme of SCOHH is to advance knowledge of marine contaminants and seafood security. Natural and anthropogenic contaminants such as mercury, DDT, and PCBs drive seafood consumption advisories. Yet understanding of their sources, microbial transformations, toxicity, and potential for climate driven change remain incomplete. The SCOHH team will study and track the distribution of essential micronutrients and harmful contaminants in marine food webs to the three billion people who consume seafood globally, the roles that the marine microbiome play in their production and transport, and the developmental toxicity of seafood pollutants and their interactions with transporters that determine uptake and bioaccumulation.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

Scripps海洋与人类健康中心（SCOHH）是为期五年的努力，旨在推进一个快速变化的星球上围绕海鲜污染物的科学和社区参与。该项目汇集了一支由生物医学和海洋学研究人员组成的多学科团队，具有鱼类生态学，微生物学，海洋化学，气候建模，技术发展，生物累积，基因组学，毒理学和公共卫生的专业知识。该中心的科学目标和重点是通过社会需求，通过双向社区参与建立的，并由一个经过验证的社区参与团队领导。 SCOHH的拟议研究计划跨越了四个主要领域：1。气候变化会影响人类海鲜微量营养素和污染物的摄入量。 2。海洋微生物组作为海鲜污染物合成，转化和分布的来源。 3。海鲜污染物的生物积累和发育毒性的机制。 4。围绕海鲜风险和利益的双向公众参与和扫盲。 SCOH的结果将为政策，消费指南和个人决策提供信息，以降低风险并增强与海鲜消费相关的更大收益。在内部，SCOH将采取故意措施，以提高其运作的各个方面的股权，多样性和包容性，从研究人员团队和研究生/博士后学员到与社区合作伙伴的交往。该中心由NSF的海洋科学部和美国国家环境健康科学研究所（NIEHS）共同支持。SCOHH的中心科学主题是提高对海洋污染物和海鲜安全的了解。天然和人为污染物（例如汞，滴滴涕和PCB）驱动海鲜消费咨询。然而，了解它们的来源，微生物转化，毒性和气候驱动变化的潜力仍然不完整。 SCOH团队将研究和跟踪海洋食品网中必不可少的微量营养素和有害污染物的分布，向全球食用海鲜食用海鲜，海洋微生物组在其生产和运输中扮演的角色以及海鲜毒性的发育毒性以及与转运者的相互作用的发育毒性，并确定了统计的人类疾病，并享受了疾病的疾病。诚实地，使用基金会的智力优点和更广泛的影响审查标准来通过评估来提供支持。