Multisensory temporal processing in early deaf adults

生命早期失去一种感觉可能会导致剩余感觉的增强。行为上的 增强通常伴随着皮质重组，在那里感觉缺失的听觉区域 被招募来处理视觉和触觉刺激。到目前为止，对早期补偿性可塑性的研究 聋人倾向于专注于单一感觉(无论是触觉还是视觉)的空间加工，而 招募被剥夺的听觉区域。结合行为和神经成像测量，目标是 这项拟议项目的目的是研究听觉剥夺对多感官的影响。 加工，并表征这些效应背后的神经机制。具体来说，我们将 确定早期耳聋是否会损害多感觉颞叶的精确度和延展性 以及这些损伤是否在空间上被调制。此外，我们还将描述 聋人多感觉时间加工的神经相关和神经动力学 右侧颞上沟(RSTs)，一个可能参与调节的多感觉区 听觉剥夺后多感官时间功能的行为改变。总而言之，这是 这项工作将提供对聋人多感官时间知觉背后的大脑机制的见解 个人。

The loss of one sense early in life can lead to an enhancement of the remaining senses. The behavioral enhancements are often accompanied by cortical reorganization, where sensory-deprived auditory regions are recruited for processing visual and tactile stimuli. To date, studies of compensatory plasticity in early deaf individuals have tended to focus on unisensory (either tactile or visual) spatial processing, and the recruitment of deprived auditory areas. Combining behavioral and neuroimaging measurements, the goals of this proposed project are to examine the effects of auditory deprivation on multisensory temporal processing, and to characterize the neural mechanisms underlying these effects. Specifically, we will determine whether early deafness impairs both the precision and the malleability of multisensory temporal integration and whether these impairments are spatially modulated. Furthermore, we will characterize neural correlates and neural dynamics of multisensory temporal processing in deaf individuals focusing on the right superior temporal sulcus (rSTS), a multisensory region that is the likely candidate mediating behavioral alterations in multisensory temporal functions following auditory deprivation. Taken together, this work will provide insights into the brain mechanisms underlying multisensory temporal perception in deaf individuals.