Calon-Cardio's Fully Implantable ventricular assist device

大多数慢性心脏病患者最终都会患上心力衰竭。随着人口老龄化和心脏病治疗的进步，心力衰竭患者的数量不断增加。虽然大多数患者在使用标准药物和手术的情况下会保持稳定数年，但越来越多的患者会出现晚期心力衰竭的症状，可能需要进行心脏移植评估。对于那些因年龄或其他医疗问题而无法等待心脏供体或不符合心脏移植条件的选定患者，心室辅助装置（VADs）提供了挽救生命的治疗和恢复良好生活质量的唯一希望。这些装置最初被设计为临时支持，为患者进行心脏移植搭建桥梁，现在被用作终身支持或目的地治疗。然而，目前的技术仍然不完善，需要管理不良事件（ae）。该项目将开发一种完全植入式VAD，专门解决当前VAD的主要弱点，通过泵提供改善的血流动力学性能，消除传动系统感染风险，降低制造和生命周期成本，并使患者能够自由地执行日常任务，不受阻碍。我们的新型FIVAD的新颖设计将汇集机械工程、电气工程、计算流体动力学和生物医学工程方面的专业知识，以提供一种新颖的泵和无线能源技术。

The majority of chronic heart disease patients ultimately suffer from heart failure. With the ageing of the population and advances in the treatment of cardiac disease, the number of patients with heart failure continues to increase. Although the majority of patients will remain stable for several years with standard medicines and surgery, a growing number will develop symptoms of advanced heart failure and may be referred for evaluation for heart transplantation. For selected patients who are too ill to wait for a heart donor or who are not eligible for a heart transplant because of age or other medical problems, ventricular assist devices (VADs) offer life-saving therapy and the only hope of returning to a good quality of life. Initially designed as temporary support to bridge patients to heart transplant, these devices are now being used as lifetime support or destination therapy. However, current technology is still imperfect with a recognised need to manage adverse events (AEs).This project will develop a Fully Implantable VAD to specifically address the main weaknesses of current VADs with a pump that offers improved haemodynamic performance, the elimination of driveline infection risk, lower manufacture and lifetime costs, and gives patients the freedom to perform everyday tasks unencumbered.The novel design of our new FIVAD will bring together expertise in mechanical engineering, electrical engineering, computational fluid dynamics, and biomedical engineering to deliver a novel pump and wireless energy technology.