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Electrochemical Oxygen Concentrator

电化学制氧机

基本信息

批准号：
10184526
负责人：
Syed Mubeen
金额：
$ 92.8万
依托单位：
UNIVERSITY OF IOWA
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-07-01 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10184526
关键词：
Address Adsorption Air Air Movements Anions Anodes Area Back COVID-19 pandemic Cannulas Carbon Cardiopulmonary Categories Cathodes Cell membrane Cells Consultations Consumption Convection Corrosion Critical Care Critical Illness Custom Developing Countries Development Device Designs Devices Diffusion Documentation Electrochemistry Electrodes Elements Emergency Care Emergency Situation Gases Generations Goals Health Personnel Home Hospitals Intubation Letters Loudness Measurement Medical Device Designs Medicine Membrane Modification Nanostructures Nanotechnology Noise Output Oxides Oxygen Patient-Focused Outcomes Patients Performance Procedures Process Production Protons Reaction Readiness Resistance Resources Risk Rural Savings Side Supplementation Surface System Technology Testing Time Translations Ventilator Water Weight Work base catalyst commercialization cost design high risk improved novel operation pandemic disease pressure prototype respiratory response sensor solid state supplemental oxygen

项目摘要

PROJECT SUMMARY Oxygen supply is essential for hospitalized patients. The limitation of resources, transport, and supply chain disruptions in the COVID-19 pandemic created some unique challenges. The simple process of providing O2 supplementation has become very challenging in a rural small hospital, a large hospital with makeshift hospital rooms, during emergency transport to the hospital, during in-hospital transport of infected patients, in developing nations with low-resource hospitals or at home for discharged patients. We propose to develop a novel oxygen concentrator that generates oxygen through electrochemical principles. The electrochemical oxygen concentrator can be especially valuable during the pandemic crisis owing to its unique merits over existing devices such as significantly higher oxygen purity (>99%) at reasonable flow rates (1 LPM – 5 LPM), lesser power consumption, less weight, less noise, and ease of manufacturing. This is a collaborative effort by an interdisciplinary team with expertise in electrochemistry, medical device design, and critical care medicine. In this two-year project, specific aim 1 involves the development of the electrochemical oxygen concentrator for in-hospital use, which includes the electrochemical core, the flow control system, and the external tower with a user interface. In specific aim 2, we will conduct rigorous tests to document various performance categories of the functional prototype – oxygen concentration, flow, operation time, power consumption, and user interface – as laid out by WHO specifications. And finally, we will conduct a technoeconomic analysis to facilitate commercialization and a quick translation to practice of the novel electrochemical oxygen concentrator.

项目概要氧气供应对于住院患者至关重要。资源、运输和供应链的限制 COVID-19 大流行造成的破坏带来了一些独特的挑战。提供 O2 的简单过程乡村小医院、方舱大医院的补给都变得非常困难病房、紧急转运至医院期间、感染患者住院转运期间、发展中医院资源匮乏或在家收治出院患者的国家。我们建议开发一种新型氧气通过电化学原理产生氧气的浓缩器。电化学制氧机由于其相对于现有设备（例如在合理的流量 (1 LPM – 5 LPM) 下显着提高氧气纯度 (>99%)，功耗更低，重量更轻，噪音更小，并且易于制造。这是跨学科团队的共同努力电化学、医疗设备设计和重症监护医学方面的专业知识。在这个为期两年的项目中，具体目标 1 涉及开发院内使用的电化学制氧机，其中包括电化学核心、流量控制系统和带有用户界面的外部塔。在具体目标 2 中，我们将进行严格的测试来记录功能原型的各种性能类别 - 氧气浓度、流量、运行时间、功耗和用户界面——按照 WHO 规范的规定。最后，我们将进行技术经济分析，以促进商业化并快速转化为新型电化学制氧机的实践.