MIS-C Program: Data Coordinating Center for the Pediatric Heart Network MIS-C Program

项目摘要/摘要 为了解决之前讨论的知识差距，美国国立卫生研究院正在发起一项全国性的研究计划，重点是 儿科SARS-CoV-2，新冠肺炎和MISC。该计划的目标是获得全面的 了解该病的表型、自然病史、转归和病理生物学。该计划将拥有 几个组成部分包括管理信息系统-C队列研究、适应性设计试验、长期跟踪和稳健的 基于云的数据平台。PHN DCC将负责协调该计划的一些组成部分。 发改委的具体目标如下： 目标1：管理核心方案业务 目标2：管理管理信息系统-C队列研究的开发、启动和传播 结果 目标3：为方案组成部分提供支助服务

PROJECT SUMMARY/ABSTRACT To address the knowledge gap discussed previously, NIH is initiating a national research program focused on pediatric SARS-CoV-2, COVID-19 and MIS-C. This goal of the program is to gain comprehensive understanding of phenotype, natural history, outcomes, and pathobiology of MIS-C. The Program will have several components including a MIS-C Cohort Study, adaptive design trials, long-term follow-up and a robust cloud-based data platform. The PHN DCC will serve to coordinate some of the components of the Program. The Specific Aims of the DCC are as follows: AIM 1: MANAGE CORE PROGRAM OPERATIONS AIM 2: MANAGE MIS-C COHORT STUDY DEVELOPMENT, LAUNCH, AND DISSEMINATION OF RESULTS AIM 3: PROVIDE SUPPORT SERVICES TO PROGRAM COMPONENTS