1Florida Alzheimer's Disease Research Center Administrative Core

作为一个资助的P50中心，目前1佛罗里达ADRC的行政核心已经成功 管理对我们的成功至关重要的复杂的多机构合作。我们还获得了 完成我们的基础设施建设所需的额外资源和资金 科学目标(例如，为额外的试验方案提供资金，~300次淀粉样蛋白PET扫描，奖学金 支持和数据管理支持)我们正在调整我们的管理核心结构和 人员应对资金机制、赠款结构的变化作出反应，以及 规划目标。这些改动旨在支持i)高度协同的 所有合作机构之间的互动，二)更加重视教育和 培训，三)列入发展项目，四)扩大临床核心活动，以 包括密歇根大学和密歇根大学的队列。特别值得一提的是，我们扩大的领导班子将 1佛罗里达州ADRC在我们的机构内扩大阿尔茨海默氏症S病(AD)和阿尔茨海默氏症 相关痴呆症(AD+ADRD)研究活动。这个领导班子还提供了一个广度 AD+ADRD研究经验，并反映了整个AD+ADRD研究的广泛焦点 机构。提出了四个目标：目标1：提供愿景、基础设施、监督和 作为一个有效的多站点ADRC，总体合规需要发挥作用。行政核心 将协调各机构的中心活动，并跟踪实现里程碑目标的进展 受时尚驱使。目标2.管理发展项目的申请、审查和授予 项目。目标3.在我们的合作中促进AD+ADRD研究和教育活动 机构和整个州。目标4.积极利用我们协作中的资源 机构、国家和其他利益攸关方推动AD+ADRD研究。

As a funded P50 center, the current 1Florida ADRC administrative core has successfully managed the complex multi-institution collaborations vital to our success. We have also garnered the additional resources and funds needed to accomplish our infrastructure generating and scientific goals (e.g., funds for additional pilot proposals, ~300 amyloid PET scans, fellowship support, and data management support) We are adapting our administrative core structure and personnel to be responsive to the change in funding mechanism, grant structure, and programmatic goals. These alterations are designed to support i) the highly synergistic interactions between all the collaborating institutes, ii) an increased emphasis on education and training, iii) inclusion of developmental projects, and iv) expansions of clinical core activities to include cohorts at UF and UM. Of particular note, our expanded leadership group positions the 1Florida ADRC well within our institutions to expand Alzheimer ’s disease (AD) and Alzheimer’s related dementias (AD+ADRD) research activities. This leadership group also provides a breadth of AD+ADRD reaserch experience and reflects the broad foci of AD+ADRD research across our institutions. Four Aims are proposed: Aim 1: Provide the vision, infrastructure, oversight, and overall compliance needed to function as an effective multi-site ADRC. The Administrative core will coordinate center activities across institutions and track progress towards goals in a milestone driven fashion. Aim 2. Manage the request for applications, review and award of developmental projects. Aim 3. Promote AD+ADRD research and educational activities among our collaborating institutions and throughout the state. Aim 4. Actively leverage resources from our collaborating institutions, the State, and other stakeholders to advance AD+ADRD research.