COVID-19, Social Distancing, and Cognitive Impairment in 1Florida ADRC participants

约560，000名阿尔茨海默病（AD）患者和> 400万居民>65 年，佛罗里达将继续成为美国AD流行病的中心。 States.佛罗里达ADRC是佛罗里达机构之间的合作， 包括佛罗里达大学（UF），Mt.位于迈阿密海滩的西奈医疗中心 （MSMC）、迈阿密大学（UM）、佛罗里达国际大学（FIU）和佛罗里达 大西洋大学（FAU）。佛罗里达州ADRC的全球使命是与其他 ADRC和AD利益相关者改变对AD和相关 因此AD+ ADRD可以更快速、更准确地诊断， 有效地治疗，并最终预防或治愈。多项研究表明， 西班牙裔和其他代表性不足的少数族裔痴呆症发病率较高 人口（URM）。我们成功招募和评估了大多数西班牙裔 队列使我们能够开始评估是否存在差异， 在南佛罗里达的西班牙裔和非西班牙裔之间的AD+ ADRD。加强我们 了解痴呆症在种族和种族多样化的人群是一个主要的 我们ADRC的主题。SARS-CoV-2或严重急性呼吸综合征 冠状病毒2型（COVID-19）大流行可能对美国 老年痴呆症认知障碍患者的健康和福祉 疾病及相关病症（ADRD）。我们相信这场大流行病已经让我们的 临床核心队列和实际上所有受AD+ADRD影响的家庭， 应力在本补充中，我们将利用我们成功的机构和调查员 进一步扩大我们的参与和纵向后续行动 具有种族、语言、文化和遗传多样性的参与者，以及 与AD相关的合并症（例如，血管疾病，路易体痴呆 （LBD））。本补编的具体目的是审查：1）社会影响 COVID-19对情绪、功能、行为和 认知状态2）认知障碍严重程度对社交距离的影响 行为。3)视频通信的使用程度和熟练程度 4）参与电信技术的兴趣程度 通过视频向参与者提供支持性小组计划 通信技术接入。

With ~560,000 Alzheimer’s disease (AD) patients and >4 million residents >65 years old, Florida will continue to be, an epicenter of the AD epidemic in the United States. The 1Florida ADRC is a collaboration between Florida institutions, including the University of Florida (UF), Mt. Sinai Medical Center in Miami Beach (MSMC), University of Miami (UM), Florida International University (FIU), and Florida Atlantic University (FAU). The 1Florida ADRC’s global mission is to work with other ADRCs and AD stakeholders to change the understanding of AD and related dementias (ADRDs) so AD+ADRDs are more quickly and accurately diagnosed, more effectively treated, and ultimately prevented or cured. Multiple studies suggest a higher incidence of dementia among Hispanics and other underrepresented minority populations (URM). Our successful recruitment and evaluation of a majority Hispanic cohort has enabled us to begin to evaluate whether there are differences in AD+ADRDs between Hispanics and non-Hispanics in South Florida. Enhancing our understanding of dementia in ethnically and racially diverse populations is a major theme of our ADRC. The SARS-CoV-2 or severe acute respiratory syndrome coronavirus type 2 (COVID-19) pandemic could prove especially detrimental to the health and well-being of individuals with cognitive impairment due to Alzheimer’s disease and related disorders (ADRD). We believe this pandemic has placed our clinical core cohort and indeed all families affect by AD+ADRD under a great deal of stress. In this supplement, we will leverage our successful institutional and investigator partnerships to further expand our engagement and longitudinal follow up of participants with ethnic, linguistic, cultural, and genetic diversity, as well as comorbidities associated with AD (e.g., vascular disease, Lewy Body Dementia (LBD)). The specific aims of this supplement are to examine: 1) Effects of social isolation stress as a result of COVID-19 on mood, function, behavior and cognitive status 2) Effects of cognitive impairment severity on social distancing behaviors. 3) Extent of access and proficiency with video communications technologies 4) Extent of interest in participation in a telecommunications delivered supportive group program among those participants with video communications technology access.