COVID-19, Social Distancing, and Cognitive Impairment in 1Florida ADRC participants

1Florida ADRC 参与者中的 COVID-19、社交距离和认知障碍

• 批准号: 10194967
• 负责人: Todd E Golde
• 金额: $ 15.4万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10194967
• 关键词: 2019-nCoV; Affect; Age; Alzheimer' s Disease; Alzheimer' s disease patient; Alzheimer' s disease related dementia; Behavior; COVID-19; COVID-19 pandemic; Caregivers; Clinical; Cognition; Cognitive; Collaborations; Communication; Cultural Diversity; Dementia; Dependence; Disease; Elderly; Epidemic; Evaluation; Family; Florida; Genetic Variation; Health; Hispanics; Impaired cognition; Incidence; Individual; Institution; International; Intervention; Lewy Body Dementia; Linguistics; Medical center; Minority; Mission; Moods; Not Hispanic or Latino; Outcome; Participant; Patients; Personal Satisfaction; Population; Population Heterogeneity; Readiness; Reporting; Research Personnel; SARS coronavirus; Severities; Social Distance; Social isolation; Social support; Stress; Support Groups; Technology; Telecommunications; Underrepresented Minority; United States; Universities; Vascular Diseases; Work; accurate diagnosis; cohort; comorbidity; coronavirus disease; ethnic diversity; follow-up; high risk; human old age (65+); interest; low socioeconomic status; pandemic disease; prevent; programs; psychosocial; racial diversity; recruit; telehealth

With ~560,000 Alzheimer’s disease (AD) patients and >4 million residents >65 years old, Florida will continue to be, an epicenter of the AD epidemic in the United States. The 1Florida ADRC is a collaboration between Florida institutions, including the University of Florida (UF), Mt. Sinai Medical Center in Miami Beach (MSMC), University of Miami (UM), Florida International University (FIU), and Florida Atlantic University (FAU). The 1Florida ADRC’s global mission is to work with other ADRCs and AD stakeholders to change the understanding of AD and related dementias (ADRDs) so AD+ADRDs are more quickly and accurately diagnosed, more effectively treated, and ultimately prevented or cured. Multiple studies suggest a higher incidence of dementia among Hispanics and other underrepresented minority populations (URM). Our successful recruitment and evaluation of a majority Hispanic cohort has enabled us to begin to evaluate whether there are differences in AD+ADRDs between Hispanics and non-Hispanics in South Florida. Enhancing our understanding of dementia in ethnically and racially diverse populations is a major theme of our ADRC. The SARS-CoV-2 or severe acute respiratory syndrome coronavirus type 2 (COVID-19) pandemic could prove especially detrimental to the health and well-being of individuals with cognitive impairment due to Alzheimer’s disease and related disorders (ADRD). We believe this pandemic has placed our clinical core cohort and indeed all families affect by AD+ADRD under a great deal of stress. In this supplement, we will leverage our successful institutional and investigator partnerships to further expand our engagement and longitudinal follow up of participants with ethnic, linguistic, cultural, and genetic diversity, as well as comorbidities associated with AD (e.g., vascular disease, Lewy Body Dementia (LBD)). The specific aims of this supplement are to examine: 1) Effects of social isolation stress as a result of COVID-19 on mood, function, behavior and cognitive status 2) Effects of cognitive impairment severity on social distancing behaviors. 3) Extent of access and proficiency with video communications technologies 4) Extent of interest in participation in a telecommunications delivered supportive group program among those participants with video communications technology access.

约56万阿尔茨海默病(AD)患者和400万居民 年了，佛罗里达州将继续成为美国AD疫情的震中 各州。佛罗里达州ADRC是佛罗里达州各机构之间的合作项目， 包括佛罗里达大学(UF)，Mt.迈阿密海滩的西奈医疗中心 (MSMC)、迈阿密大学(UM)、佛罗里达国际大学(FIU)和佛罗里达 大西洋大学(FAU)。1佛罗里达ADRC的全球使命是与其他 ADRC和AD利益相关者改变对AD及其相关的理解 痴呆(ADRD)因此可以更快、更准确地诊断AD+ADRD，更多 有效治疗，并最终预防或治愈。多项研究表明， 西班牙裔和其他代表性不足的少数族裔中痴呆症的发病率较高 种群(URM)。我们成功地招募和评估了大多数西班牙裔 队列已使我们能够开始评估是否存在差异 南佛罗里达州拉美裔和非拉美裔之间的AD+ADRD。增强我们的 了解不同民族和种族人群中的痴呆症是一个主要的 我们亚洲发展研究中心的主题。SARS-CoV-2或严重急性呼吸综合征 2型冠状病毒(新冠肺炎)的大流行可能对 阿尔茨海默病认知障碍患者的健康和幸福感 疾病及相关障碍(ADRD)。我们相信这场大流行已经把我们的 临床核心队列，实际上是所有受AD+ADRD影响的家庭 压力。在本增刊中，我们将利用我们成功的机构和研究人员 进一步扩大我们的接触和纵向后续行动的伙伴关系 具有种族、语言、文化和遗传多样性的参与者，以及 与阿尔茨海默病相关的并发症(如血管疾病、路易体痴呆 (LBD))。本附录的具体目的是考察：1)社会影响 新冠肺炎引起的隔离应激对情绪、功能、行为和行为的影响 认知状况2)认知障碍严重程度对社交距离的影响 行为。3)视频通信的使用范围和熟练程度 技术4)参与电信业务的兴趣程度 通过视频在参与者中提供支持性小组计划 通信技术接入。