HIV Co-morbidities Research Training in Ghana (HIV-ComRT)

项目摘要 在加纳拟议的艾滋病毒共病研究培训(HIV-ComRT)建立并扩大了我们的 持续成功的短期(8周)夏季强化辅导研究培训-加纳研究 学者计划-自2007年以来在耶鲁为来自加纳的实习生提供奖学金。《加纳研究学者》的目的 计划是在加纳建立和加强生物医学研究能力；这一目标与 资助机会公告的总体目标(PAR-19-283；Fogarty艾滋病毒研究培训 面向LMIC机构的方案)。培训方案的组成部分和内容由 与加纳大学(UG)和其他机构的教职员工和领导层进行咨询需求评估 加纳的利益攸关方(卫生部、加纳卫生服务和国家艾滋病控制计划)。我们 将招收具有医学博士、硕士或博士学位的实习生，并向他们传授理论和应用知识 在研究方法、设计和实施研究研究的技能以及终身职业指导方面 加纳艾滋病毒相关合并症和混合感染的成功调查。的正式程序 每个实习生都会有所不同，这取决于他/她之前的培训和目前的职业计划。主要的地点是 无论是在UG还是在耶鲁，培训将取决于学员的需求，但所有学员都将接触到 这两个机构的资源。我们将为学员提供：(1)在两个研究设计方面有坚实的基础 以及适用于临床、翻译和实验室研究的分析技术；(2)能够 批判性地对研究问题进行概念化和分析，并增加独立性；(3)经验 科学写作、发表和发表研究成果；(4)指导实验室管理和 临床项目；以及(5)研究和职业发展方面的指导。这些将通过三个方面来实现 具体目标：(1)为UG的实习生和其他初级教员提供以下方面的理论和应用知识 研究方法；(2)通过为期两年的强化和辅导，使学员掌握研究技能 艾滋病毒方面的博士后研究培训；以及(3)为华盛顿大学的受训人员建立和维护导师计划，以 成为独立资助的调查人员。在五年资助期内，我们预计将招收14名学员。 高级学位(4名博士和10名硕士(硕士或公共卫生硕士))，并提供为期两年的博士后强化课程 为五名博士后/初级教员提供研究培训。此外，约200名研究生，博士后研究员， UG的初级教职员工和研究科学家将从研究和职业发展研讨会中受益。 受训人员将具有不同的研究兴趣，以确保我们在团队科学方面建立能力 对艾滋病毒相关的合并症和混合感染进行跨学科研究。技能 他们通过我们的重点教学培训计划，与不同的学者群体互动，在 一个多学科的学术社区，以及与杰出科学家的指导研究经验(在 UG和耶鲁)将为他们在艾滋病毒相关合并症的研究生涯中取得成功提供工具。

Project Summary The proposed HIV Comorbidities Research Training (HIV-ComRT) in Ghana builds and expands on our ongoing successful short-term (8 weeks) summer intensive mentored-research training—the Ghana Research Scholar Program—at Yale for trainees from Ghana since 2007. The aim of the Ghana Research Scholar Program is to build and strengthen biomedical research capacity in Ghana; this aim dovetails with the overarching aim of the Funding Opportunity Announcement (PAR-19-283; Fogarty HIV Research Training Program for LMIC Institutions). The components and content of the training program were informed by a consultative need assessment with faculty and leadership at the University of Ghana (UG) and other stakeholders in Ghana (Ministry of Health, Ghana Health Service, and National AIDS Control Program). We will recruit trainees with MD, Master's, or PhD degrees and equip them with theoretical and applied knowledge in research methods, skills in designing and conducting research studies, and life-long career coaching to be successful investigators in HIV-associated comorbidities and coinfections in Ghana. The formal program of each trainee will vary, depending on his/her prior training and current career plans. The predominant site for training, either at UG or Yale, will depend on the needs of the trainee, however, all trainees will be exposed to resources at both institutions. We will provide trainees with: (1) a strong foundation in both research design and analytic techniques appropriate for clinical, translational, and laboratory-based research; (2) the ability to conceptualize and analyze research problems critically and with increasing independence; (3) experience in scientific writing, presenting and publishing research findings; (4) instruction in management of laboratory and clinical projects; and (5) mentorship in research and career development. These will be achieved through three Specific Aims: (1) to provide trainees and other junior faculty at UG with theoretical and applied knowledge in research methods; (2) to equip trainees with research skills through a two-year intensive and mentored postdoctoral research training in HIV; and (3) to establish and maintain a mentorship plan for trainees at UG to become independently funded investigators. During the 5-year grant period, we expect to enroll 14 trainees in advanced degrees (four PhDs and ten Master's (MSc or MPH)) and provide a two-year intensive postdoctoral research training for five postdocs/junior faculty. In addition, about 200 graduate students, postdoc fellows, junior faculty, and research scientists at UG will benefit from the research and career development workshops. The cohort of trainees will have diverse research interests to ensure that we build capacity in team science in executing cross- and inter-disciplinary research in HIV-associated comorbidities and coinfections. The skills that they gain through our program of focused didactic training, interactions with a diverse group of scholars in a multidisciplinary academic community, and a mentored research experience with outstanding scientists (at UG and Yale) will provide them with the tools for successful research careers in HIV-associated comorbidities.