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中文摘要
翻译
项目概要/摘要-核心A:行政核心 ! 行政核心将提供具有成本效益和集中的组织、行政、协调, 作为更大的CMCRC的成员,监督、支持和管理INTERACT联盟, 促进实现联合会的总体目标。该核心将提供行政和 管理监督,有效和积极主动的领导,并强调项目和 核心领导支持医疗对策(MCM)的开发。核心A将确保科学严谨性 通过辐射物理/剂量测定支持和生物统计监督。核心A还将监督 认证计划,确保适当的随机化,设盲和对照组,并尽量减少生物学 在所有实验研究中要求使用两种性别,从而增加了变异性。核心A也将鼓励新的机会 研究合作以及学生和早期职业专业人士的教育和培训感兴趣 在辐射科学和MCM中。核心A由一名全职项目经理、一名项目管理员、 还有一个会计该核心还包括一个由工业界组成的外部科学咨询小组, 监管和科学专家。为了衡量成功和监测进展,行政核心将 每月与所有项目领导和核心主管举行会议,每半年对运营进行一次战略审查, 年度研究撤退。必要时将举行特别会议。战术评价将每两年进行一次 确保项目在范围内、按时、按预算进行。核心A将提供健全的财政管理, 为政府提供最佳价值。核心A将与协调中心核心密切协调, 所有数据都与NIAID/NIH的项目官员、项目范围内的CMCRC和一般领域共享, 尽快。 !
英文摘要
PROJECT SUMMARY/ABSTRACT - CORE A: ADMINISTRATIVE CORE ! The Administrative Core will provide cost-effective and centralized organization, administration, coordination, monitoring, support, and management of the INTERACT Consortium as a member of the larger CMCRC to facilitate achievement of the overall goals of the Consortium. This Core will provide administrative and managerial oversight, effective and proactive leadership, and emphasize INTERACTions among Project and Core Leads to support the development of medical countermeasures (MCM). Core A will ensure scientific rigor through radiation physics/dosimetry support and biostatistical oversight. Core A will also provide oversight of authentication plans, ensure appropriate randomization, blinding, and control groups, and minimize biological variability by requiring use of both sexes in all experimental studies. Core A will also encourage new opportunities for research collaborations as well as education and training of students and early career professionals interested in the radiation sciences and MCMs. Core A is supported by a full-time project manager, a program administrator, and an accountant. The Core also includes an External Scientific Advisory Group (ESAG) comprised of industry, regulatory, and scientific experts. To measure success and monitor progress, the Administrative Core will hold a monthly meeting with all Project Leads and Core Directors, a biannual strategic review of operations, and an Annual Research Retreat. Ad hoc meetings will be held as needed. Tactical evaluations will take place biannually to ensure projects remain in scope, on time, and on budget. Core A will provide sound fiscal management to ensure best value to the government. Core A will coordinate closely with the Coordinating Center Core to ensure that all data is shared with program officers at NIAID/NIH, the program-wide CMCRC, and the field in general as rapidly as possible. !
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Development of BIO 300 for mitigation and/or treatment of radiation pneumonitis and fibrosis
  • 批准号:
    10401463
  • 项目类别:
  • 资助金额:
    $37.43万
  • 财政年份:
    2020
  • 负责人:
    Isabel Lauren Jackson
  • 依托单位:
Development of BIO 300 for mitigation and/or treatment of radiation pneumonitis and fibrosis
  • 批准号:
    10845829
  • 项目类别:
  • 资助金额:
    $38.47万
  • 财政年份:
    2020
  • 负责人:
    Isabel Lauren Jackson
  • 依托单位:
Administrative Core
  • 批准号:
    10845823
  • 项目类别:
  • 资助金额:
    $22.53万
  • 财政年份:
    2020
  • 负责人:
    Isabel Lauren Jackson
  • 依托单位:
Development of BIO 300 for mitigation and/or treatment of radiation pneumonitis and fibrosis
  • 批准号:
    10194370
  • 项目类别:
  • 资助金额:
    $40.74万
  • 财政年份:
    2020
  • 负责人:
    Isabel Lauren Jackson
  • 依托单位:
海外基金