Administrative Core

项目摘要/摘要--核心A：行政核心 好了！ 行政核心将提供具有成本效益和集中化的组织、行政、协调、 作为更大的CMCRC的成员，监测、支持和管理InterAct联盟，以 促进财团总体目标的实现。该核心将提供管理和 管理监督、有效和主动的领导，并强调项目和 核心导致支持医学对策(MCM)的发展。核心A将确保科学严谨 通过辐射物理/剂量学支持和生物统计监督。核心A还将监督 身份验证计划，确保适当的随机化、盲化和控制组，并最大限度地减少生物 在所有的实验研究中都需要使用两性的可变性。核心A还将鼓励新的机会 用于研究合作以及对感兴趣的学生和职业早期专业人员进行教育和培训 在放射科学和医学医学方面。核心A由一名全职项目经理、一名项目管理员、 还是个会计。核心还包括一个由工业界组成的外部科学咨询小组(ESAG)， 监管专家和科学专家。为了衡量成功和监测进展，行政核心将举行 每月与所有项目负责人和核心总监举行会议，一年两次的运营战略审查，以及 年度研究务虚会。如有需要，将举行特别会议。战术评估将每两年进行一次 确保项目在规模、时间和预算范围内。核心A将提供健全的财政管理，以 确保为政府带来最佳价值。核心A将与协调中心核心密切协调，以确保 所有数据都与NIAID/NIH的项目官员、整个项目范围的CMCRC以及整个外地共享为 越快越好。 好了！

PROJECT SUMMARY/ABSTRACT - CORE A: ADMINISTRATIVE CORE ! The Administrative Core will provide cost-effective and centralized organization, administration, coordination, monitoring, support, and management of the INTERACT Consortium as a member of the larger CMCRC to facilitate achievement of the overall goals of the Consortium. This Core will provide administrative and managerial oversight, effective and proactive leadership, and emphasize INTERACTions among Project and Core Leads to support the development of medical countermeasures (MCM). Core A will ensure scientific rigor through radiation physics/dosimetry support and biostatistical oversight. Core A will also provide oversight of authentication plans, ensure appropriate randomization, blinding, and control groups, and minimize biological variability by requiring use of both sexes in all experimental studies. Core A will also encourage new opportunities for research collaborations as well as education and training of students and early career professionals interested in the radiation sciences and MCMs. Core A is supported by a full-time project manager, a program administrator, and an accountant. The Core also includes an External Scientific Advisory Group (ESAG) comprised of industry, regulatory, and scientific experts. To measure success and monitor progress, the Administrative Core will hold a monthly meeting with all Project Leads and Core Directors, a biannual strategic review of operations, and an Annual Research Retreat. Ad hoc meetings will be held as needed. Tactical evaluations will take place biannually to ensure projects remain in scope, on time, and on budget. Core A will provide sound fiscal management to ensure best value to the government. Core A will coordinate closely with the Coordinating Center Core to ensure that all data is shared with program officers at NIAID/NIH, the program-wide CMCRC, and the field in general as rapidly as possible. !