Human Health Exposure Analysis Resource (HHEAR): Coordinating Center

项目摘要/摘要 国家环境健康科学研究所(NIEHS)正在建立一个基础设施，即人类 健康暴露分析资源(HHEAR)，为校外研究社区提供访问 实验室和统计分析，以增加或扩大其研究中的环境暴露。 HHEAR将由三个部分组成：一个协调中心(CC)，一个国家暴露评估 实验室网络，以及用于统计分析和方法的暴露数据存储库和资源 发展。该项目将为HHEAR实施CC。HHEAR将提供一系列复杂的 向接触科学和健康研究界提供实验室分析和数据服务。主要目标是 CC的目的是为研究人员提供一个方便、统一的界面，让他们能够访问 这个复杂的网络。CC将(1)创建和维护HHEAR实验室和 为研究人员提供数据服务、方法和专门知识；(2)提供一个公共网站，作为 研究人员获取有关HHEAR能力的信息并提出使用建议的主要手段 HHEAR的资源；(3)建立和管理提案提交和评估流程；(4)监督 已批准提案的进度和跟踪服务工作流程；(5)定义质量标准，以 将衡量HHEAR的表现；(6)支持实验室分析标准化和 流程；(7)组织和支持HHEAR监督委员会；(8)管理试点和可行性 计划；(9)为HHEAR制定和实施战略沟通计划；(10)确定外部 对接触科学和健康研究感兴趣的资源；以及(11)利用HHEAR公共网站 和社交媒体向更广泛的科学界宣传HHEAR的可用资源和成就 社区。

PROJECT SUMMARY/ABSTRACT The National Institute of Environmental Health Sciences (NIEHS) is establishing an infrastructure, the Human Health Exposure Analysis Resource (HHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research. HHEAR will be composed of three components: a Coordinating Center (CC), a National Exposure Assessment Laboratory Network, and an Exposure Data Repository and Resource for Statistical Analysis and Methods Development. This project will implement the CC for HHEAR. HHEAR will provide a range of sophisticated laboratory analyses and data services to the exposure science and health research community. The main goal of the CC is to provide researchers with a convenient and unified interface to access the available services of this complex network. The CC will (1) create and maintain a comprehensive index of HHEAR laboratory and data services, methodologies, and expertise available to researchers; (2) provide a public website as the primary means for researchers to access information about HHEAR’s capabilities and initiate proposals to use HHEAR’s resources; (3) establish and manage processes for proposal submission and evaluation; (4) monitor the progress of approved proposals and track services workflow; (5) define the quality standards by which the performance of HHEAR will be measured; (6) support the standardization of laboratory analyses and processes; (7) organize and support HHEAR oversight committees; (8) manage a Pilot and Feasibility Program; (9) develop and implement a strategic communication plan for HHEAR; (10) identify external resources of interest to exposure science and health research; and (11) leverage the HHEAR public website and social media to promote HHEAR’s available resources and accomplishments to the broader scientific community.