Children's Health Exposure Analysis Resource (CHEAR): Coordinating Center

儿童健康暴露分析资源 (CHEEAR)：协调中心

• 批准号: 9060558
• 负责人: BARBARA O'BRIEN
• 金额: $ 499.74万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-30 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9060558
• 关键词: Access to Information; Birth; Cessation of life; Chemicals; Child; Child health care; Communication; Communities; Complex; Data; Data Analyses; Databases; Development; Ensure; Environmental Exposure; Evaluation; Exposure to; Extramural Activities; Future; Genes; Goals; Health; House Staffs; Human; Institution; Laboratories; Leadership; Life Style; Measures; Medical Research; Methodology; Monitor; National Children' s Study; National Institute of Environmental Health Sciences; Ontology; Performance; Process; Research; Research Infrastructure; Research Personnel; Resources; Risk Assessment; Science; Scientist; Services; Standardization; System; United States National Institutes of Health; Vision; Work; design; developmental toxicology; experience; flexibility; health data; health science research; improved; indexing; innovation; insight; interest; meetings; method development; programs; psychosocial; public health relevance; quality assurance; social; statistics; success; tool; web site

 DESCRIPTION (provided by applicant): The National Institute of Environmental Health Sciences (NIEHS) is establishing an infrastructure, the Children's Health Exposure Analysis Resource (CHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research. CHEAR will be composed of three components: a Coordinating Center (CC), a National Exposure Assessment Laboratory Network, and an Exposure Data Repository and Resource for Statistical Analysis and Methods Development. This project will implement the CC for CHEAR. CHEAR will provide a range of sophisticated laboratory analyses and data services to the exposure science and children's health research community. The main goal of the CC is to provide researchers with a convenient and unified interface to access the available services of this complex network. The CC will create and maintain a comprehensive index of CHEAR laboratory and data services, methodologies, and expertise available to researchers; provide a public website as the primary means for researchers to access information about CHEAR's capabilities and initiate proposals to use CHEAR's resources; establish and manage processes for proposal submission and evaluation; monitor the progress of approved proposals and track services workflow; define the quality standards by which the performance of CHEAR will be measured; support the standardization of laboratory analyses and processes; organize and support CHEAR oversight committees; establish and manage a Pilot and Feasibility Program; develop a strategic communication plan for CHEAR; identify external resources of interest to exposure science and children's health research; and leverage the CHEAR public website and social media to facilitate communication with the broader scientific community.

 描述（由申请人提供）：国家环境健康科学研究所（NIEHS）正在建立一个基础设施，即儿童健康暴露分析资源（CHEARS），为校外研究社区提供实验室和统计分析，以增加或扩大其研究中的环境暴露。该中心将由三个部分组成：一个协调中心（CC）、一个国家接触评估实验室网络、一个接触数据储存库和统计分析和方法开发资源。本项目将执行《儿童权利公约》。CHEMICAL将为接触科学和儿童健康研究界提供一系列复杂的实验室分析和数据服务。CC的主要目标是为研究人员提供一个方便和统一的接口来访问这个复杂网络的可用服务。CC将创建和维护一个全面的索引，介绍研究人员可获得的CHESTIC实验室和数据服务、方法和专业知识;提供一个公共网站，作为研究人员获取有关CHESTIC能力信息的主要手段，并提出使用CHESTIC资源的建议;建立和管理建议提交和评估流程;监测已批准建议的进展情况，并跟踪服务工作流程;确定质量标准，通过它的性能将被衡量;支持实验室分析和流程的标准化;组织和支持CHDSPs监督委员会;建立和管理试点和可行性计划;制定CHDSPs的战略沟通计划;确定感兴趣的接触科学和儿童健康研究的外部资源;并利用CHEMICAL公共网站和社交媒体促进与更广泛的科学界的沟通。