Core A: Administrative Core

核心摘要 行政核心（核心 A）由耶鲁大学 SPORE 肺科首席研究员 Roy Herbst 指导 癌症 (YSILC)，由 Ed Kaftan 联合指导，并得到项目财务管理团队的支持。 行政核心的认真监督对于确保耶鲁 SPORE 在肺部的成功至关重要 癌症。 Core A 是 YCC 研究管理部门提供的现有基础设施的扩展，用于支持 并促进跨学科研究工作。行政核心作为中央协调 所有 YSILC 调查员的重点，负责监控所有项目和核心的进展，以实现 转化/临床终点。核心董事和联合董事以及YISLC Co-PI（陈博士） 负责领导 YSILC 项目、设定转化研究优先事项、确定新的 来自新兴数据的转化研究机会，监测所有项目、核心和 开发项目并确定项目、核心和转化研究方向的变化 需要。核心 A 促进了 YSILC 研究人员之间的互动，以加速研究的转化 实验室研究结果纳入拟议的和未来的临床研究。如果需要，核心 A 总监将负责管理 YSILC 调查员之间的冲突。作为一个团队，核心人员监控财务、维护 项目和核心领导人之间的沟通和协调会议，包括每周的肺癌会议 翻译小组研讨会系列、执行委员会月度会议、翻译小组年会 内部/外部顾问委员会以及年度 YSILC SEP 和 DRP 研讨会。除了这些 功能，核心是与 NCI、其他肺癌 SPORE、耶鲁癌症中心和 耶鲁大学，并协调外展工作，包括出版物（内部和外部）、网站 开发、研讨会、患者/研究宣传活动和筹款计划。通过这些 管理活动，核心 A 对于 YSILC 计划的组织、开发 耶鲁大学肺癌基础/临床/转化研究的广泛文化和高效成果 既定的计划目标，最终目标是对肺病患者产生重大临床影响 癌症。

CORE SUMMARY The Administrative Core (Core A) is directed by Roy Herbst, Principal Investigator of the Yale SPORE in Lung Cancer (YSILC), and co-directed by Ed Kaftan, with support from the program financial management team. Careful oversight by the Administrative Core will be critical to ensure the success of the Yale SPORE in Lung Cancer. Core A is an extension of existing infrastructure provided by YCC Research Administration to support and facilitate transdisciplinary research efforts. The Administrative Core serves as the central coordination point for all YSILC investigators, with responsibility for monitoring the progress of all projects and cores toward a translational/clinical endpoint. The Core Director and Co-Director along with the YISLC Co-PI (Dr. Chen) have responsibility for leading the YSILC program, setting translational research priorities, identifying new translational research opportunities from emerging data, monitoring the progress of all projects, cores and developmental projects and determining changes in direction of projects, cores and translational research as needed. Interactions among YSILC investigators is facilitated by Core A to accelerate the translation of laboratory findings into the proposed and future clinical studies. If required, the Core A Director will manage conflicts among YSILC investigators. As a team, the Core personnel monitors finances, maintains communications among project and core leaders and coordinates meetings, including the weekly lung cancer translational group seminar series, monthly meetings of the Executive Committee, annual meetings of the Internal/External Advisory boards and the annual YSILC SEP and DRP Symposium. In addition to these functions, the Core is the primary interface with the NCI, other lung cancer SPOREs, Yale Cancer Center and Yale University, and coordinates outreach efforts, including publications (internal and external), website development, seminars, patient/research advocacy activities, and fundraising programs. Through these administrative activities, Core A is essential to the organization of the YSILC program, to developing a widespread culture of lung cancer basic/clinical/translational research at Yale and to the efficient achievement of the stated program objectives, with the ultimate goal of a significant clinical impact for patients with lung cancer.