Administrative Core
行政核心
基本信息
- 批准号:8931832
- 负责人:
- 金额:$ 86.07万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-08-26 至 2020-07-31
- 项目状态:已结题
- 来源:
- 关键词:AchievementAdvocacyAdvocateBasic ScienceBiologyBostonCancer CenterClinicalClinical ResearchClinical TrialsCollaborationsCommunicationConflict (Psychology)ConsultationsDataDevelopmentDisputesEnsureEvaluationFoundationsFund RaisingFundingFutureGoalsGrantHospitalsHuman ResourcesHuman Subject ResearchInstitutionIsraelLaboratory FindingLeadershipMalignant neoplasm of lungMedicalMonitorNational Cancer InstituteOccupational activity of managing financesPatientsPreparationPrincipal InvestigatorProgram EvaluationProgress ReportsPublicationsRegulationResearchResearch InfrastructureResearch PersonnelResearch PriorityResearch Project GrantsResourcesSeriesSourceTimeLineTranslational ResearchTranslationsUnited States National Institutes of HealthUniversitiesWorkYale Cancer Centeranticancer researchbasecareer developmentcost effectivemeetingsneoplasm resourcenoveloperationoutreachpersonalized medicinepre-clinicalprogramssuccessweb site
项目摘要
CORE SUMMARY
The Administrative Core (Core A) will be directed by Roy Herbst, Principal -Investigator of the Yale SPORE in
Lung Cancer (YSILC), and co-directed by Ed Kaftan, with support from the program financial management
team. Careful oversight by the Administrative Core will be critical to ensure the success of the Yale SPORE in
Lung Cancer. Core A is an extension of existing infrastructure provided by YCC Research Administration to
support and facilitate transdisciplinary research efforts. The Administrative Core serves as the central
coordination point for all YSILC investigators, with responsibility for monitoring the progress of all projects and
cores toward a translational/clinical endpoint. The Core Director and Co-Director along with the YSILC Co-PI
(Dr. Chen) will have responsibility for leading the YSILC program, setting translational research priorities,
identifying new translational research opportunities from emerging data, monitoring the progress of all projects,
cores and developmental projects and determining changes in direction of projects, cores and translational
research as needed. Interactions among YSILC investigators will be facilitated by Core A to accelerate the
translation of laboratory findings into the proposed and future clinical studies. If required, the Core A Director
will manage conflicts among YSILC investigators. As a team, the Core personnel will monitor finances,
maintain communications among project and core leaders and coordinate meetings, including the weekly lung
cancer translational group seminar series, monthly meetings of the Executive Committee, annual meetings of
the Internal/External Advisory boards and an annual YSILC retreat. In addition to these functions, the Core will
be the primary interface with the NCI, the Beth Israel Deaconess Medical Cancer Center, other lung cancer
SPOREs, Yale Cancer Center and Yale University, and will coordinate outreach efforts, including publications
(internal and external), website development, seminars, patient/research advocacy activities, and fundraising
programs. Through these administrative activities, Core A will be essential to the organization of the YSILC
program, to developing a widespread culture of lung cancer basic/clinical/translational research at Yale and to
the efficient achievement of the stated program objectives, with the ultimate goal of a significant clinical impact
for patients with lung cancer
核心摘要
管理核心(核心A)将由耶鲁大学SPORE的首席研究员Roy Herbst指导,
肺癌(YSILC),由艾德卡夫坦共同指导,并得到项目财务管理的支持
团队行政核心的仔细监督对于确保耶鲁大学SPORE的成功至关重要。
肺癌核心A是YCC研究管理局提供的现有基础设施的扩展,
支持和促进跨学科的研究工作。行政核心作为中央
所有YSILC调查员的协调点,负责监测所有项目的进展情况,
核心向转化/临床终点发展。核心总监和联席总监沿着YSILC联席PI
(Dr. Chen)将负责领导YSILC项目,确定转化研究的优先事项,
从新兴数据中发现新的转化研究机会,监控所有项目的进展,
核心和发展项目,并确定项目方向的变化,核心和翻译
根据需要进行研究。核心A将促进YSILC调查人员之间的互动,以加快
将实验室结果转化为拟议和未来的临床研究。如果需要,核心A主管
将管理YSILC调查员之间的冲突。作为一个团队,核心人员将监督财务,
保持项目和核心领导人之间的沟通,协调会议,包括每周一次的会议。
癌症翻译小组研讨会系列,执行委员会每月会议,
内部/外部咨询委员会和YSILC年度务虚会。除了这些功能,核心将
成为NCI的主要接口,贝丝以色列女执事医疗癌症中心,其他肺癌
SPORE、耶鲁癌症中心和耶鲁大学,并将协调外展工作,包括出版物
(内部和外部),网站开发,研讨会,患者/研究宣传活动和筹款
程序.通过这些行政活动,核心A对青年收入和生活中心的组织至关重要
计划,发展肺癌基础/临床/转化研究在耶鲁大学的广泛文化,
有效实现规定的计划目标,最终目标是产生重大的临床影响
肺癌患者
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Roy S Herbst其他文献
Ultrastructural
- DOI:
10.1038/labinvest.2012.25 - 发表时间:
2012-02-01 - 期刊:
- 影响因子:0
- 作者:
Vamsidhar Velcheti;Kurt A Schalper;Daniel E Carvajal;Valsamo K Anagnostou;Konstantinos N Syrigos;Mario Sznol;Roy S Herbst;Scott N Gettinger;Lieping Chen;David L Rimm - 通讯作者:
David L Rimm
The end of the beginning: progress and next steps in emKRAS/em-mutant non-small-cell lung cancer
开端的终结:emKRAS/em 突变型非小细胞肺癌的进展与下一步措施
- DOI:
10.1016/s0140-6736(23)00288-x - 发表时间:
2023-03-04 - 期刊:
- 影响因子:88.500
- 作者:
Sarah B Goldberg;Roy S Herbst - 通讯作者:
Roy S Herbst
Pan-genomic/Pan-proteomic Approaches to Diseases
- DOI:
10.1038/labinvest.2012.19 - 发表时间:
2012-02-01 - 期刊:
- 影响因子:0
- 作者:
Vamsidhar Velcheti;Kurt A Schalper;Daniel E Carvajal;Valsamo K Anagnostou;Konstantinos N Syrigos;Mario Sznol;Roy S Herbst;Scott N Gettinger;Lieping Chen;David L Rimm - 通讯作者:
David L Rimm
Efficacy and safety of first-line maintenance therapy with lurbinectedin plus atezolizumab in extensive-stage small-cell lung cancer (IMforte): a randomised, multicentre, open-label, phase 3 trial
芦比替定联合阿替利珠单抗作为广泛期小细胞肺癌一线维持治疗的疗效与安全性(IMforte):一项随机、多中心、开放标签的3期试验
- DOI:
10.1016/s0140-6736(25)01011-6 - 发表时间:
2025-06-14 - 期刊:
- 影响因子:88.500
- 作者:
Luis Paz-Ares;Hossein Borghaei;Stephen V Liu;Solange Peters;Roy S Herbst;Katarzyna Stencel;Margarita Majem;Mehmet Ali Nahit Şendur;Grzegorz Czyżewicz;Reyes Bernabé Caro;Ki Hyeong Lee;Melissa L Johnson;Nuri Karadurmuş;Christian Grohé;Sofia Baka;Tibor Csőszi;Jin Seok Ahn;Raffaele Califano;Tsung-Ying Yang;Yasemin Kemal;Martin Reck - 通讯作者:
Martin Reck
A process to reanalyze clinical DNA sequencing data for biomarker matching in the Lung-MAP Master Protocol
在 Lung-MAP Master Protocol 中重新分析临床 DNA 测序数据以进行生物标志物匹配的过程
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:0
- 作者:
J.W. Neal;K. Minichiello;Ryan Brennick;Richard S P Huang;Matthew C. Hiemenz;Cornel Amler;Jyoti D. Patel;Roy S Herbst;K. Reckamp;Hossein Borghaei;Louise Highleyman;M. Redman;L. Pasquina;D. Kozono - 通讯作者:
D. Kozono
Roy S Herbst的其他文献
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{{ truncateString('Roy S Herbst', 18)}}的其他基金
Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung Cancer
耶鲁 SPORE 肺癌 (YSILC):肺癌的生物学和个性化治疗
- 批准号:
10203850 - 财政年份:2015
- 资助金额:
$ 86.07万 - 项目类别:
Yale SPORE in Lung Cancer Developmental Research Program
耶鲁大学 SPORE 肺癌发展研究项目
- 批准号:
10203857 - 财政年份:2015
- 资助金额:
$ 86.07万 - 项目类别:
Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung Cancer
耶鲁 SPORE 肺癌 (YSILC):肺癌的生物学和个性化治疗
- 批准号:
9767058 - 财政年份:2015
- 资助金额:
$ 86.07万 - 项目类别:
Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung Cancer
耶鲁 SPORE 肺癌 (YSILC):肺癌的生物学和个性化治疗
- 批准号:
9338869 - 财政年份:2015
- 资助金额:
$ 86.07万 - 项目类别:
Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung Cancer
耶鲁 SPORE 肺癌 (YSILC):肺癌的生物学和个性化治疗
- 批准号:
8931829 - 财政年份:2015
- 资助金额:
$ 86.07万 - 项目类别:
MicroRNA-based interventions to prevent progression from lung preneoplasia to adenocarcinoma
基于 MicroRNA 的干预措施可预防肺肿瘤前期发展为腺癌
- 批准号:
9379210 - 财政年份:2015
- 资助金额:
$ 86.07万 - 项目类别:
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