CCRATE - Cardiac Circadian Rhythm Automated Trend Establishment

CCRATE - 心脏昼夜节律自动趋势建立

• 批准号: 10039795
• 金额: $ 32.46万
• 依托单位: DIGITAL & FUTURE TECHNOLOGIES LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10039795
• 关键词: CCRATE; Cardiac; Circadian; Rhythm; Automated

The CCRATE project takes the results of the company's long running physiological signal AI programme and develops a consumer health system for the establishment of continuous Blood Pressure analysis.The project uses new advances in AI to generate a Blood Pressure reading every 10 beats of the subject's heart without the need for an inflatable cuff.For too many years diagnosis of hypertension have been made through wholly unreliable, inaccurate, uncomfortable inflatable cuffs.We aim to change that and to create a solution that works for consumers using their smartphones paired with already certified stick on sensors.At just 17g the chosen sensor solution can be worn for 7 days and is showerproof. In that 7-day period we analyse typically around 600,000 heart data points and generate up to 60,000 Blood Pressure readings. This level of analysis has never previously been achieved on a consumer health device.The project develops the end to end data network between stick-on sensor and user's smartphone. It bridges the gap between app and medical device, and provides a new and novel means to analyse people's cardiac performance, their Blood Pressure and links it all to their Circadian Rhythm.Blood pressure fluctuates with a pattern that follows a circadian rhythm, with a peak in the early morning hours and a trough during sleep. This rhythm originates in a "master oscillator" located in the brain.This is the cutting edge of consumer healthcare, blending AI algorithms with advances in high-fidelity physiological measurements.The output of the project will be commercialised through partnerships with specific industry organisations and sectors.It is time we moved away from the inflatable cuff Blood Pressure device that is responsible for the onset of white coat hypertension as well as providing numerous questions over its reliability/suitability as a consumer health device.

CCRATE项目采用了该公司长期运行的生理信号AI项目的结果，并开发了一个消费者健康系统，用于建立连续的血压分析。该项目使用AI的新进展，每10次受试者的心脏跳动就产生一个血压阅读，而不需要充气袖带。多年来，高血压的诊断一直是通过完全不可靠，不准确，不舒服的充气袖口。我们的目标是改变这种情况，并为消费者提供一种解决方案，让他们的智能手机与已经认证的粘贴式传感器配对。所选的传感器解决方案仅需17克，可以佩戴7天，并且可以防水。在这7天的时间里，我们通常分析大约60万个心脏数据点，并生成多达6万个血压读数。该项目开发了粘贴式传感器和用户智能手机之间的端到端数据网络。它弥补了应用程序和医疗设备之间的差距，并提供了一种新的和新颖的手段来分析人们的心脏性能，他们的血压，并将其全部与他们的昼夜节律联系起来。血压波动的模式遵循昼夜节律，在清晨的高峰和睡眠期间的低谷。这种节律起源于大脑中的“主振荡器”。这是消费者医疗保健的前沿，将人工智能算法与先进的保真度生理测量。该项目的产出将通过与特定行业组织和部门的合作伙伴关系实现商业化。现在是我们摆脱充气袖带血压设备的时候了，这种设备也是导致白色大衣高血压的原因因为其作为消费者健康设备的可靠性/适用性存在许多问题。