Clinical Studies Core

临床研究核心

• 批准号: 10204697
• 负责人: BRYAN O BUCHHOLZ
• 金额: $ 8124.2万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-17 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10204697
• 关键词: 2019-nCoV; Address; Adherence; Affect; Android; Ants; Assisted Living Facilities; Bedside Testings; Boston; Businesses; COVID-19 pandemic; Care Technology Points; Caregivers; Cessation of life; Characteristics; Child; Chronic Obstructive Airway Disease; Clinical; Clinical Research; Clinical Sciences; Communities; Consent; Data; Day center care; Detection; Development; Device or Instrument Development; Devices; Diagnosis; Discipline of Nursing; Disease; Elderly; Engineering; Enrollment; Environment; Event; Funding; General Hospitals; Geography; Goals; Gold; HIV; Health; Healthcare; Heart Diseases; Hematological Disease; Home environment; Homelessness; Immunocompromised Host; Income; Incubators; Individual; Infection; Infrastructure; Institution; Institutional Review Boards; Laboratories; Lead; Logistics; Lung diseases; Massachusetts; Medical; Medical Device; Mentors; Migrant Workers; Military Personnel; Morbidity - disease rate; National Heart, Lung, and Blood Institute; National Institute of Biomedical Imaging and Bioengineering; Nursing Homes; Online Systems; Participant; Patients; Performance; Plants; Population; Predictive Value; Pregnant Women; Protocols documentation; Religion and Spirituality; Reproducibility; Research; Research Design; Research Support; Resources; Restaurants; Rural; Rural Community; Safety; Schools; Sensitivity and Specificity; Site; Sleep Disorders; Socioeconomic Status; Sports; Subway; Target Populations; Technology; Testing; Training; Translational Research; Transportation; United States National Institutes of Health; Universities; Validation; Veterans; Vision; Work; Workplace; Youth; after-school program; base; clinical center; cohort; commercialization; community building; cost; data management; diagnosis standard; flexibility; health care availability; health care settings; human subject protection; improved; industry partner; innovation; medical schools; mortality; new technology; novel; performance tests; practice-based research network; programs; success; technology development; usability; viral detection; working group

RESEARCH SUMMARY/ABSTRACT The goal of this initiative is to fast-track the implementation of carefully selected CAPCaT-supported projects that can help address the urgent healthcare issues created by the COVID-19 pandemic. The extent and urgency of the situation requires an aggressive approach to accelerate the delivery of solutions to address the immediate needs. The proposed approach augments the strong technical, clinical and commercialization expertise of CAPCaT to get needed solutions into practice within weeks to months. The Center for Advancing Point of Care Technologies (CAPCaT) in Heart, Lung, Blood, and Sleep Diseases is an offshoot of a highly successful medical product incubator, the Massachusetts Medical Device Development Center (M2D2) at the University of Massachusetts Lowell and Medical School campuses. The founding goal of M2D2 was to accelerate the development of medical devices, combining the engineering and business expertise of UMass Lowell (UML) with the clinical expertise of UMass Medical School (UMMS) in Worcester. Expanding upon the vision and success of M2D2, the goal of CAPCaT is to support projects to develop and optimize novel point of care technologies (POCT) to improve the diagnosis and management of heart, lung, blood, and sleep diseases. We have focused on these diseases because of the significant morbidity, mortality, and cost associated with these diseases. Combined, these diseases account for 41% of deaths in the US and lead to over $400B in direct health care expenses plus lost income to affected patients and caregivers. UMass has an established track record of clinical expertise and technology development in the HLBS diseases. CAPCaT funds projects that are in the later stages of POCT development, with a focus on the clinical validation of those devices. CAPCaT, along with M2D2, has a network of industry partners and funders to support the development and commercialization of promising technologies. Among our industry partners are Johnson & Johnson, Boston Scientific, Amgen, and Hologic. CAPCaT is one of four Point of Care Technology Research Network (POCTRN) Centers (Emory/GA Tech, Northwestern, and Johns Hopkins University house the others). CAPCaT has worked with the other POCTRN Centers and its Coordinating Center (CIMIT-Mass General Hospital) and our scientific and program officers at NHLBI and NIBIB to review the situation and to understand unmet needs and resources accessible by the network that can make a difference.

研究总结/文摘