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The Center for Advancing Point of Care in Heart, Lung, Blood and Sleep Diseases

心脏、肺、血液和睡眠疾病护理点推进中心

基本信息

批准号：
10735580
负责人：
BRYAN O BUCHHOLZ
金额：
$ 181.84万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-22 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10735580
关键词：
Acceleration Address Adoption Advisory Committees Affect American Automobile Driving Blood Businesses COVID-19 pandemic COVID-19 testing Cardiovascular system Caregivers Caring Cessation of life Client satisfaction Clinic Clinical Clinical Research Communication Community Health Data Decision Making Development Device or Instrument Development Diagnosis Disease Disparity Engineering Environment Equitable healthcare Family Funding Goals Grant Health Health Personnel Health Professional Health Promotion Health system Healthcare Heart Heart Diseases Hematological Disease Home Income Incubated Incubators Intellectual Property Knowledge Legal patent Life Lung Lung diseases Marketing Massachusetts Medical Medical Device Mentors Methodology Modeling Morbidity - disease rate Needs Assessment Outcome Pathway interactions Patients Point of Care Technology Policy Maker Population Heterogeneity Prevention Process Provider Quality of Care Research Research Personnel Resource-limited setting Resources Risk Running Sleep Sleep Disorders System Technology Telemedicine Therapeutic Time Training Underserved Population United States National Institutes of Health Universities Vision Work acute care clinical development commercialization community engagement cost design evidence base experience health care availability health care quality health equity health management home test improved industry partner innovation marginalized population medical schools mortality new technology novel patient engagement patient oriented personalized management point of care prevent programs research clinical testing success technology research and development tool trend trial design virtual healthcare

项目摘要

Project Summary/Abstract – Overall Core American healthcare is rapidly evolving to a state where efficiency, quality and patient satisfaction are dominant drivers. Several trends are driving fundamental changes in health care: 1) an expanding scope of virtual care and telemedicine, accelerated by the COVID-19 pandemic, has changed how patients, healthcare providers, and health systems interact; 2) a growing recognition of disparities leading to an emphasis in providing healthcare equitably for historically marginalized populations; 3) an increasing appreciation for the patient as a critical stakeholder in therapeutic decision-making, leading to an emphasis on patient-centered design; and 4) increasing access to home health to enable better diagnosis, prevention and management of health conditions, as illustrated by widespread adoption of home-testing for SARS-CoV-2. Despite this rapidly changing environment, heart (cardiovascular), lung, blood, and sleep disorders (HLBS) continue to cause significant morbidity, mortality, and cost in the US and worldwide. Combined, these diseases account for 41% of deaths in the US and lead to over $400B in direct health care expenses plus lost income to affected patients and caregivers. Thus, there are urgent unmet needs in HLBS. We will address these issues with the renewal of the Center for Advancing Point of Care Technologies (CAPCaT) in HLBS Disorders. CAPCaT is a highly successful Point-of-Care Technology Research Network (POCTRN) Center that leverages our experience running a medical product incubator, the Massachusetts Medical Device Development Center (M2D2) at the University of Massachusetts (Lowell and Worcester campuses), and our experience administering grants, running, and managing solicitations, and working 1:1 with awardees to advance their technologies toward commercialization. CAPCaT expanded upon the original vision and success of M2D2 and now has its own established track record and collaborative network to develop and optimize novel POC and home-based technologies to improve the diagnosis and management of HLBS disorders. Our objectives in achieving this goal are to continue: 1) identifying, through stakeholder engagement, the most promising POC and home-based technologies to address unmet medical needs; 2) supporting developmental plans, including pathways to adoption at the point of care or in the home; and 3) training and disseminating developing POC and home-based technologies to the different stakeholders.

项目摘要/摘要-整体核心

项目成果

期刊论文数量（45）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Respiratory Adenovirus Quantification with a Droplet Digital Polymerase Chain Reaction (ddPCR) Assay.

使用微滴数字聚合酶链式反应 (ddPCR) 测定进行呼吸道腺病毒定量。

DOI：
10.1128/spectrum.00269-23
发表时间：
2023-06-15
期刊：
Microbiology spectrum
影响因子：
3.7
作者：
通讯作者：

Dynamic pH and Thermal Analysis of Paper-Based Microchip Electrophoresis.

DOI：
10.3390/mi12111433
发表时间：
2021-11-22
期刊：
Micromachines
影响因子：
3.4
作者：
Hasan MN;An R;Akkus A;Akkaynak D;Minerick AR;Kharangate CR;Gurkan UA
通讯作者：
Gurkan UA

N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection.

DOI：
10.1038/s41467-021-22072-9
发表时间：
2021-03-26
期刊：
Nature communications
影响因子：
16.6
作者：
Shan D;Johnson JM;Fernandes SC;Suib H;Hwang S;Wuelfing D;Mendes M;Holdridge M;Burke EM;Beauregard K;Zhang Y;Cleary M;Xu S;Yao X;Patel PP;Plavina T;Wilson DH;Chang L;Kaiser KM;Nattermann J;Schmidt SV;Latz E;Hrusovsky K;Mattoon D;Ball AJ
通讯作者：
Ball AJ

Emerging point-of-care technologies for anemia detection.

DOI：
10.1039/d0lc01235a
发表时间：
2021-05-18
期刊：
Lab on a chip
影响因子：
6.1
作者：
An R;Huang Y;Man Y;Valentine RW;Kucukal E;Goreke U;Sekyonda Z;Piccone C;Owusu-Ansah A;Ahuja S;Little JA;Gurkan UA
通讯作者：
Gurkan UA

Increased circulation of human adenovirus in 2023: an investigation of the circulating genotypes, upper respiratory viral loads, and hospital admissions in a large academic medical center.