Research Methods Core

项目摘要 为了对艾滋病毒流行病产生最大影响，应对酗酒问题的干预措施应包括： 艾滋病毒预防和护理的评价和实施必须强调现实世界的有效性， 可扩展性和可持续性。与此相一致的是，这部分支持布朗的中心主题 大学酒精研究中心对艾滋病毒（艾滋病）涉及评估新的方法来解决酒精 在国内和全球的艾滋病毒预防和护理环境中使用， 干预措施、远程保健和最先进的实施战略。研究方法核心（RMC）是 一个共享的资源，将支持共同体的组成研究组成部分的相互需要， 在以下方面提供援助：（1）数据收集、管理、协同和分析;（2）技术辅助 评估和干预;（3）实施科学。在生物统计学教师的贡献下， 数字健康和实施科学，以及经验丰富的数据管理和编程人员， RMC将通过创建数据收集工具和干预组件直接支持这些需求， 开发参与者和数据管理系统，编写脚本以汇编和统一数据集 跨多个来源，并促进数据归档。RMC人员还将提供以下咨询： 研究设计，评估最佳做法，并将导致在每个主要统计分析提出 项目最后，RMC人员将为每个项目的实施科学方法提供持续的指导。 项目，汇编关于实施科学框架和方法的资源，并提供教育和 关于执行科学专题的培训。因此，RMC核心提供的资源将使 研究部分利用研究设计和数据分析领域的最佳做法，并确保 他们所做的研究是严格的，并取得了最大的影响。为数据提供一般支持 通过风险管理委员会的管理还可以确保在每个项目中使用一致的方法， 在可能的情况下进行协调，并有效地存档和共享数据。它还创建了一个 规模经济，一项研究中使用的数据管理任务可以更容易地应用于其他研究， 避免了每个研究本身开发和支持这些方法的需要。最后，提供一个 关于执行科学问题的培训和指导的共享资源将使每个项目能够利用 在该领域的最佳做法，并最终帮助推进其整合和维持酒精的目标 在实践环境中的干预。

Project Summary To achieve the most impact on the HIV epidemic, interventions that address alcohol misuse in the context of HIV prevention and care must be evaluated and implemented with an emphasis on real-world effectiveness, scalability, and sustainability. Consistent with this, the central theme of this segment of support for the Brown University Alcohol Research Center on HIV (ARCH) involves evaluating novel methods of addressing alcohol use in HIV prevention and care contexts both domestically and globally, using technology-delivered interventions, telehealth, and state-of-the-art implementation strategies. The Research Methods Core (RMC) is a shared resource that will support the mutual needs of the ARCH’s constituent research components by providing assistance with (1) data collection, management, synergy, and analysis, (2) technology-assisted assessments and interventions, and (3) implementation science. With contributions from faculty in biostatistics, digital health, and implementation science, as well as experienced data management and programming staff, the RMC will directly support these needs by creating data collection instruments and intervention components, developing participant and data management systems, authoring scripts to compile and harmonize datasets across multiple sources, and facilitate data archiving. RMC personnel will also provide consultation on research design, assessment best-practices, and will lead primary statistical analyses proposed in each project. Finally, RMC personnel will provide ongoing guidance on implementation science methods for each project, compile resources on implementation science frameworks and methods, and offer education and training on implementation science topics. As such, the resources provided by the RMC core will enable the research components to utilize best-practices in the areas of study design and data analysis and ensure that the research they produce is rigorous and achieves the most impact. Providing general support for data management through the RMC can also ensure that consistent approaches are used in each project, that data are harmonized whenever possible, and that data are archived and shared efficiently. It also creates an economy of scale, where data management tasks used in one study can more easily be applied across others, obviating the need for each study to develop and support these methods themselves. Finally, providing a shared resource for training and guidance on implementation science issues will enable each project to utilize best practices in the field and ultimately help advance each toward its goal of integrating and sustaining alcohol interventions in practice settings.