Component for Institution # 264313

试点项目核心将为新的倡议和可行性研究提供关键支持，以进行测试 药物滥用、疼痛和成瘾领域的新假设和新数据 研究，以及滥用药物与艾滋病毒的交集。受支持范围的研究 涉及各种学科和技术，包括分子、药理学、生理学、 免疫学的和行为学的。项目涉及包括阿片类药物在内的各种药物类别， 大麻素、精神刺激剂、酒精和尼古丁。支持的数量足以 允许测试新想法并积累可用于形成基础的数据 申请外部资金。除了支持该项目的实际资金外， 鼓励研究人员利用研究的专业知识和设施 NIDA P30中心的支持核心。研究支持核心的使用使 实施试点项目，通过获得新的援助来扩大他们的专业领域 他们可能不熟悉的技术和方法，并接受他们的指导 核心教职员工。在上一个供资期间，有三个项目/年得到了试点项目的支持 项目核心，产生了最近授予的NIDA R01以及其他提交的赠款 申请、若干出版物以及在国家和区域会议上的发言。 通过向坦普尔学院的教职员工发布一般性和针对性的公告来征集潜在的申请者 通过专业名单服务向大学和其他机构的教职员工提供服务。申请 试点项目支持由P30中心教职员工组成的小组委员会进行评估，并根据 他们的创新点和研究意义的问题和方法，概率 将获得足够的结果作为独立赠款的初步数据 应用，以及与NIDA P30中心目标整合的优势。特价 考虑到早期职业调查人员和新进入该领域的调查人员 药物滥用研究。通过非正式和频繁的讨论来评估进展情况 获奖者的进展和正式报告。预计将有三个试点项目 每年由试点项目核心直接支持，包括每年至少两个新项目 年。

The Pilot Project Core will provide critical support for new initiatives and feasibility studies to test new hypotheses and generate novel data in the field of substance abuse, pain and addiction research, and the intersection of drugs of abuse with HIV. Research that is supported ranges over a variety of disciplines and techniques including molecular, pharmacological, physiological, immunological, and behavioral. Projects involve a variety of drug classes including opioids, cannabinoids, psychostimulants, alcohol and nicotine. The amount of support is sufficient to allow the testing of new ideas and accumulating data that can be used to form the basis for an application for external funding. In addition to the actual dollars supporting the project, the investigators are encouraged to make use of the expertise and the facilities of the Research Support Cores of the NIDA P30 Center. Use of the Research Support Cores allows those carrying out a Pilot Project to expand their areas of expertise by receiving assistance with new techniques and approaches with which they may be unfamiliar, and to receive mentoring from the Core faculty. In the previous funding period, three projects/year were supported by the Pilot Projects Core, resulting in a recently awarded NIDA R01 as well as other submitted grant applications, several publications, and presentations at national and regional meetings. Potential applicants are solicited by general and targeted announcements to faculty at Temple University and to faculty of other institutions through professional list-serves. Applications for pilot project support are evaluated by a sub-committee of P30 Center faculty and are judged on their innovation and significance of the research question and approach, the probability that sufficient outcomes will be obtained to serve as preliminary data for an independent grant application, and the strength of the integration with the aims of the NIDA P30 Center. Special consideration is given to early career investigators and to investigators new to the field of substance abuse research. Progress is evaluated via informal and frequent discussions of progress and formal reports from awardees. It is anticipated that three pilot projects will be supported directly by the Pilot Project Core each year, including at least two new projects per year.