Surgical Oncology Research Training Program

项目总结 在过去的三十年里，我们目睹了对分子的理解的爆炸性增长 人类疾病的潜在机制。然而，从这些知识中得出了相对较少的 成功的新奇疗法。从历史上看，外科肿瘤学家在这一进程中发挥了至关重要的作用。 以癌症为导向的疗法。此外，卫生服务研究对优化医疗保健越来越重要。 外科肿瘤科患者。然而，外科医生参与研究工作受到了严重挑战。 由于不断增长的外科培训需求和当前医疗保健环境的复杂性。更多 比以往任何时候都更重要的是，我们将严格的科学培训作为我们外科培训计划不可或缺的一部分。 阿拉巴马大学外科肿瘤学研究培训计划的主要重点是- 伯明翰(UAB)旨在通过激发兴趣来加强外科肿瘤学学术研究培训 医生-科学家在肿瘤学方面进行翻译和卫生服务研究培训。只有一个人 这种性质的计划存在于南方腹地，因此，19名普通外科手术的居民 在南方腹地的常驻项目被引导到其他资助的研究培训领域。 外科肿瘤学研究培训计划的总体计划目标是提供外科手术 住院医生，有强烈的外科肿瘤学职业动机，有全面的，有指导的 研究经验。该计划的具体目标是：1)提供基本的、 通过个体参与和量身定做的转化和健康服务外科肿瘤学研究 利用UAB外科部门的广泛资源进行教学和指导计划 综合癌症中心(CCC)，医学院临床和转化科学中心 (CCTS)，博士后教育办公室(OPE)，以及大量的卫生服务和差距 研究计划和中心；2)培养外科医生-科学家和学术外科领域的领导者 强调外科肿瘤学；以及3)扩大外科科学家的队伍，他们将在未来具有竞争力 研究事业发展和独立研究补助金。该应用程序包括一组成功的、 来自各种外科肿瘤学相关学科的经验丰富的培训师，研究重点如下 研究领域：癌症病因和进展、暴露生物学、实验治疗学、化学预防、 癌症预后和存活率的差异。项目负责人拥有丰富的过去经验 研究培训计划。该计划通过以下途径解决外科肿瘤学研究的不断发展的领域 纳入生物统计和生物信息学、基因组学和差异方面的培训方案。通过其强大的 癌症研究环境和承诺培训，UAB和UAB外科提供 为这个需要的项目找到一个最理想的家。

PROJECT SUMMARY Over the last three decades, we have witnessed an explosion in the understanding of the molecular mechanisms underlying human disease. However, out of this knowledge has come a relatively small number of successful novel therapies. Historically, surgical oncologists have played an essential role in the advancement of cancer-directed therapies. Additionally, health services research is increasingly important to optimizing care of surgical oncology patients. However, surgeon participation in research efforts has been seriously challenged by ever growing surgical training demands and the complexity of the current health care environment. More than ever it is critical that we make rigorous scientific training an integral part of our surgical training programs. The principal focus of the Surgical Oncology Research Training Program at the University of Alabama- Birmingham (UAB) is to strengthen academic surgical oncology research training by stimulating interested physician-scientists to pursue translational and health services research training in oncology. Only one other program of this nature exists in the Deep South and as a result, residents in the 19 general surgery residency programs in the Deep South are steered toward other funded fields of research training. The overall program goal of the Surgical Oncology Research Training Program is to provide surgical residents, who are strongly motivated toward a career in surgical oncology, with a comprehensive, mentored research experience. The specific objectives of this program are to: 1) provide training in the conduct of basic, translational and health services surgical oncology research through participation in an individual and tailored didactic and mentoring program utilizing the extensive resources of the UAB Department of Surgery, UAB Comprehensive Cancer Center (CCC), the School of Medicine’s Center for Clinical and Translational Science (CCTS), the Office of Postdoctoral Education (OPE), and an abundance of health services and disparities research programs and centers; 2) develop surgeon-scientists and leaders in academic surgery with an emphasis on surgical oncology; and 3) expand the pool of surgeon-scientists who will be competitive for future research career development and independent research grants. The application includes a pool of successful, experienced trainers from a variety of surgical oncology-related disciplines with research in the following focus areas: cancer etiology and progression, exposure biology, experimental therapeutics, chemoprevention, disparities in cancer outcomes and survivorship. Program leaders have significant past experience with research training programs. The program addresses the evolving field of surgical oncology research through the inclusion of training options in biostatistics and bioinformatics, genomics and disparities. Through its robust cancer research environment and commitment to training, UAB and the UAB Department of Surgery provide an optimal home for this needed program.