Surgical Oncology Research Training Program

肿瘤外科研究培训计划

• 批准号: 10767059
• 负责人: HERBERT CHEN
• 金额: $ 51.29万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-16 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10767059
• 关键词: Research Training; Surgical Oncology; Training Programs

PROJECT SUMMARY Cancer remains one of the most common causes of death in the United States, second only to cardiovascular disease. Great need exists for continued research to prevent cancer and improve outcomes. Surgeon-scientists are uniquely positioned to translate research findings associated with surgical diseases to the bedside and operating room. Despite their unique expertise and effectiveness in research, the role of the surgeon-scientist has historically been threatened for the last few decades. Surgeon-scientists are submitting fewer career development awards and have lower success rates in obtaining NIH funding. There has been only small growth in the percentage of surgeons funded by NIH in the past 10 years, but surgical oncologists represent the largest group of surgeon subspecialists receiving NIH grants. It is critical that we continue to expand this pool of investigators and develop surgeon-scientists in the field of oncology. The overall program goal of the Surgical Oncology Research Training Program at the University of Alabama at Birmingham (UAB) is to provide surgical residents who are strongly motivated toward a career in surgical oncology with a comprehensive, mentored research and training experience that prepares them for successful careers as surgeon-scientists. The program provides surgeon-scientists who intend to enter a career in academic surgery, particularly in surgical oncology, with the opportunity for basic, translational, and health services research training in a mentored, multidisciplinary, collaborative environment. The program leverages the extensive resources of the UAB Department of Surgery, UAB O’Neal Comprehensive Cancer Center (CCC), the UAB Heersink School of Medicine’s Center for Clinical and Translational Science (CCTS), the Office of Postdoctoral Education (OPE), and an abundance of health services and disparities research programs and centers. The program includes a pool of outstanding extramurally funded trainers from a variety of cancer-related disciplines. Seven trainees have completed the program; 1 has obtained a faculty position with NCI funding, and 6 are continuing their clinical training in environments that will facilitate their continued success in developing independent academic careers. An additional 4 are currently appointed. Several have obtained additional degrees to advance their scientific knowledge, and several have been successful in obtaining additional funding to support their fellowship training or further career development. While this is a new program, it has already been successful in developing its first NIH-funded surgeon-scientist. It has also attracted a diverse group of trainees, including 27% African American and 82% female. Trainees have demonstrated excellent productivity as evidenced by publications and national presentations. These early markers of success are clear indicators of the program’s future ability to produce extramurally funded surgeon-scientists in the field of surgical oncology.

项目摘要 癌症仍然是美国最常见的死亡原因之一，仅次于 心血管疾病非常需要继续研究以预防癌症和改善结果。 外科医生-科学家处于独特的地位，可以将与外科疾病相关的研究结果转化为 床边和手术室尽管他们在研究方面具有独特的专业知识和效率， 外科医生科学家在过去几十年里一直受到威胁。外科医生科学家们正在提交 职业发展奖较少，获得NIH资助的成功率较低。出现 在过去的10年里，NIH资助的外科医生的比例只有小幅增长，但外科肿瘤学家 代表了接受NIH赠款的最大的外科专家小组。我们必须继续 扩大这一研究人员库，并在肿瘤学领域培养外科医生-科学家。 该外科肿瘤学研究培训计划的总体计划目标在大学的 亚拉巴马在伯明翰（UAB）是提供外科住院医生谁是对职业生涯的强烈动机， 外科肿瘤学与全面的，指导的研究和培训经验，准备他们 作为外科医生科学家的成功职业该计划提供外科医生科学家谁打算进入一个 学术外科的职业生涯，特别是在外科肿瘤学，有机会进行基础，翻译， 卫生服务研究培训在指导，多学科，协作环境。程序 利用UAB外科的广泛资源，UAB O 'Neal综合癌症 中心（CCC），UAB Heersink医学院临床和转化科学中心（CCTS）， 博士后教育办公室（OPE），以及大量的卫生服务和差异研究 方案和中心。该计划包括一个优秀的校外资助培训师从各种池 与癌症相关的学科。7名学员已完成该计划; 1人已获得教职 在NCI的资助下，有6人正在继续他们的临床培训， 成功发展独立的学术生涯。目前另有4人获得任命。几个已经 获得了额外的学位，以提高他们的科学知识，有几个已经成功地在 获得额外的资金，以支持他们的研究金培训或进一步的职业发展。虽然这是一个 新计划，它已经成功地开发了第一个NIH资助的外科医生科学家。它有 还吸引了不同的学员群体，包括27%的非洲裔美国人和82%的女性。学员 出版物和国家情况介绍都证明了这一点。 这些早期的成功标志是该计划未来生产能力的明确指标 在外科肿瘤学领域的校外资助的外科医生科学家。

项目成果

Multidisciplinary clinics for colorectal cancer may not provide more efficient coordination of care.

• DOI: 10.1016/j.amjsurg.2021.11.027
• 发表时间: 2022-06
• 期刊: AMERICAN JOURNAL OF SURGERY
• 影响因子: 3
• 作者: Bajpai, Swara;Wood, Lauren;Cannon, Jamie A.;Chu, Daniel I.;Hollis, Robert H.;Gunnells, Drew J.;Hardiman, Karin M.;Kennedy, Gregory D.;Morris, Melanie S.
• 通讯作者: Morris, Melanie S.

A pediatric case of xanthogranulomatous pyelonephritis in the setting of Covid-19 and multi-system inflammatory syndrome (MIS-C).

• DOI: 10.1016/j.epsc.2022.102359
• 发表时间: 2022-09
• 期刊: JOURNAL OF PEDIATRIC SURGERY CASE REPORTS
• 影响因子: 0.4
• 作者: Julson, Janet R.;Noor, M. D. Sibat;Williams, Adele P.;Wicker, Jason;Beierle, Elizabeth A.
• 通讯作者: Beierle, Elizabeth A.

Participant perspectives on a department of surgery faculty mentoring program.

参与者对外科教员指导计划的看法。

• DOI: 10.1016/j.amjsurg.2022.10.060
• 发表时间: 2023
• 期刊: American journal of surgery
• 影响因子: 3
• 作者: Gillis,Andrea;Zmijewski,Polina;Corey,Britney;Fazendin,Jessica;Chen,Herbert;Lindeman,Brenessa;Hendershot,Kimberly;Dream,Sophie
• 通讯作者: Dream,Sophie

The association of social vulnerability with colorectal enhanced recovery program failure.

社会脆弱性与结直肠加速康复计划失败的关联。

• DOI: 10.1016/j.sopen.2023.03.007
• 发表时间: 2023
• 期刊: Surgery open science
• 影响因子: 1.4
• 作者: Smith,BurkelyP;Hollis,RobertH;Shao,ConnieC;Gleason,Lauren;Wood,Lauren;McLeod,MarshallC;Kay,DanielleI;Oates,GabrielaR;Pisu,Maria;Chu,DanielI
• 通讯作者: Chu,DanielI

EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth.

• DOI: 10.1371/journal.pone.0246244
• 发表时间: 2021
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Bownes LV;Williams AP;Marayati R;Stafman LL;Markert H;Quinn CH;Wadhwani N;Aye JM;Stewart JE;Yoon KJ;Mroczek-Musulman E;Beierle EA
• 通讯作者: Beierle EA