Pilot Projects Program

摘要 试点项目路易斯维尔大学糖尿病和肥胖的首要使命 该中心旨在加强和丰富对心脏代谢健康和疾病机制的研究。 根据这一使命，COBRE第三阶段的试点项目计划将提供财政、技术和 为糖尿病、肥胖症和心血管生物学领域的试点项目提供智力支持。申请人 该计划将主要由路易斯维尔大学各学术部门的初级教师组成 他们对发展心脏代谢疾病的研究项目感兴趣。此外，有价值的 由职业中期和高级调查员提交的项目，建议改变领域或指导他们的未来 心血管或代谢疾病的研究将被考虑资助。试点项目赠款 申请将每年征集一次，并根据审查结果颁发，为期不超过两年。 以及内部赠款评估员和外部咨询委员会的建议。此外，我们将 为每位获奖者提供强大的导师团队，以监督他们的项目发展， 获得联邦资助并提供职业指导。该方案的具体目标是：（1） 支持创新心脏代谢研究;（2）提供科学和专业指导， 接受者;（3）加强糖尿病和肥胖中心的竞争力;（4）监测效率 试点项目的有效性。我们将鼓励那些有很高可能性的项目， 与和推进当前中心的知识和能力。这种做法将有助于确保 我们增加了中心的调查人员数量，并增强了我们进行基本和 翻译研究

ABSTRACT PILOT PROJECT PROGRAM. The overarching mission of the University of Louisville Diabetes and Obesity Center is to enhance and enrich research into the mechanisms underlying cardiometabolic health and disease. In line with this mission, the Pilot Project Program of Phase III of the COBRE will provide financial, technical, and intellectual support to pilot projects in the areas of diabetes, obesity, and cardiovascular biology. Applicants for the Program will derive primarily from junior faculty within academic departments at the University of Louisville who have an interest in developing research programs in cardiometabolic disease. Additionally, meritorious projects submitted by mid-career and senior investigators proposing to change fields or direct their future research toward cardiovascular or metabolic disease will be considered for funding. Pilot project grant applications will be solicited annually and awarded for a period of not more than two years based on the review and recommendations of internal grant evaluators and the External Advisory Committee. In addition, we will provide each awardee with a strong mentorship team to chaperone the development of their projects to the level required for federal funding and to provide career guidance. The specific objectives of the program are to: (1) support innovative cardiometabolic research; (2) provide scientific and professional mentorship to award recipients; (3) strengthen the competitiveness of the Diabetes and Obesity Center; and (4) monitor efficiency and effectiveness of the pilot program. We will encourage projects that have a high probability of both integrating with and advancing the knowledge and capabilities of the current Center. This approach will help ensure that we increase the mass of investigators in the Center as well as augment our ability to conduct basic and translational research.