Conduct Hit-to-Lead Progression Studies on Interventional Agents: Identification of Anti-HIV Lead Compounds

艾滋病毒治疗和局部杀微生物剂的体外测试资源：开发和引进新的艾滋病毒治疗和局部杀微生物剂仍然是公共卫生的一个高度优先事项。为了帮助填补这些公共卫生空白，NIAID支持来自学术界、私营部门或其他来源的有前途的治疗性和局部杀微生物剂候选药物的临床前开发。该合同提供标准和HTS格式的体外测试，并进行临床前开发研究，以确定有前途的抗艾滋病毒治疗和局部杀微生物剂。

In Vitro Testing Resource for HIV Therapeutics and Topical Microbicides: The development and introduction of new therapeutics and topical microbicides against HIV remains a high public health priority. To assist in filling these public health gaps, the NIAID supports preclinical development of promising therapeutic and topical microbicide candidates that emerge from academia, the private sector, or other sources. This contract provides in vitro testing, in standard and HTS formats, and conducts preclinical development studies to identify promising anti‐HIV therapeutics and topical microbicides.