4/5 HEAL Consortium: Establishing Innovative Approaches for the HEALthy Brain and Child Development Study

4/5 HEAL 联盟：建立健康大脑和儿童发展研究的创新方法

• 批准号: 10217747
• 负责人: STEPHANIE L MERHAR
• 金额: $ 16.93万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10217747
• 关键词: Address; Adult; Affect; Age-Months; Anxiety; Arkansas; Behavior; Brain; COVID-19; COVID-19 pandemic; Child; Child Development; Child Health; Child Rearing; Cognitive; Cohort Studies; Development; Dimensions; Environment; Equipment; Equipment and supply inventories; Family; Family Relationship; Future; Geography; Home environment; Individual; Infant; Infection; Institution; Manuals; Measurement; Measures; Mental Health; Mothers; North Carolina; Parent-Child Relations; Parents; Participant; Pediatric Hospitals; Perinatal; Persons; Phase; Protocols documentation; Psychometrics; Questionnaires; Research; Research Institute; Safety; Schools; Site; Stress; Surveys; Testing; Time; Training; Transcend; Uncertainty; United States; United States National Institutes of Health; Universities; Validation; Variant; Visit; cognitive development; cost; experience; innovation; learning materials; pandemic disease; phase 1 study; phase 2 study; physical conditioning; social; virtual

PROJECT SUMMARY/ABSTRACT The COVID-19 pandemic has affected the mental and physical health of children and their parents. The pandemic has also affected the ability to conduct in-person research at most institutions across the United States. However, recent technological advances may allow many in-person assessments to transition to virtual formats. There is an urgent need to develop virtual versions of currently used assessments of the home environment and parent-child interactions, and to concurrently study the effect of the COVID-19 pandemic on family relationships. The proposed project seeks to address this urgent need by building upon ongoing research efforts among three sites from the NIH HEALthy Brains and Cognitive Development (HBCD) study: Arkansas Children’s Research Institute, Cincinnati Children’s Hospital, and the University of North Carolina at Chapel Hill. We will develop and test a virtual version of the HOME Inventory in 90 mothers with infants between 6-18 months of age. We will validate this virtual version by performing in-person HOME Inventory assessments in 45 of these dyads. In all participants, we will use standard questionnaires to assess COVID-19 exposure and impact. Finally, we will examine associations between regional and temporal variations in COVID-19 exposure and impact and dimensions of the HOME Inventory. The results of this study will be used to finalize the development of a virtual HOME Inventory protocol that can be widely used in future studies, including the HBCD Phase II study.

项目概要/摘要 COVID-19 大流行影响了儿童及其父母的身心健康。这 大流行还影响了美国大多数机构进行现场研究的能力 国家。然而，最近的技术进步可能允许许多现场评估过渡到虚拟评估 格式。迫切需要开发当前使用的家庭评估的虚拟版本 环境和亲子互动，并同时研究 COVID-19 大流行对 家庭关系。拟议项目旨在通过现有项目的基础上解决这一迫切需求 NIH 健康大脑和认知发展 (HBCD) 研究三个中心的研究工作： 阿肯色州儿童研究所、辛辛那提儿童医院和北卡罗来纳大学 教堂山。我们将开发虚拟版本的 HOME Inventory，并在 90 位有婴儿的母亲中进行测试 6-18 个月大。我们将通过亲自执行家庭库存来验证此虚拟版本 对其中 45 个二元组进行评估。在所有参与者中，我们将使用标准问卷来评估 COVID-19 曝光度和影响。最后，我们将研究区域和时间变化之间的关联 COVID-19 暴露、影响以及家庭库存的规模。本研究的结果将用于 完成可广泛用于未来研究的虚拟 HOME 库存协议的开发， 包括六溴环十二烷二期研究。