University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC)

项目概要（总体） 这份来自迈阿密大学（UM）的发展性艾滋病研究中心（UM D- ARC）建议在美国建立一个行为科学中心，以推进心理健康（MH）艾滋病毒研究。 是艾滋病毒/艾滋病感染最严重的地区。过度关注中心的主题是“减少心理健康的影响 艾滋病毒预防和护理持续存在的少数群体健康差异”，直接关系到 在大迈阿密地区不受控制的艾滋病毒/艾滋病流行，这一发展资金将提供一个 这是一个动态增长到后续全面ARC应用的途径。在最初的融资期内，我们将 巩固、协调和增加机构资源，发展和扩大区域和 国家合作。迈阿密是美国艾滋病发病率和流行率最高的城市， 从地理上讲，对每一个疾病控制中心的艾滋病毒影响指标。在UM开发专注于MH的D-ARC也是 高度的公共卫生意义，因为迈阿密的多样化人口面临着显着的MH差异，使该地区 这是在受流行病影响不成比例的不同人群中进行MH研究的理想环境。 UM D-ARC核心的组织代表了一种逻辑和创新的方法， D-ARC在一个拥有越来越多的行为科学家骨干和增加艾滋病毒的战略目标的机构中 research.我们建议所需的行政（管理）核心和发展（开发）核心和两个 （而不是必需的）补充研究核心：方法核心和心理健康 差异（MHD）核心。管理核心将体现中心领导、治理和战略规划 并协调双向社区参与活动，这是所有核心工作的关键。的 Dev Core将专注于奖励试点研究和指导早期研究人员。核心方法将 提供创新的研究设计，生物统计和数据管理专业知识，并与 MHD Core构建、扩展和维护中心通用数据元素（CDE），同意联系 数据库和一个REDCap措施库，以最大限度地实现资源共享。MHD Core将提供 专门知识和资源，以促进文化上胜任的，理论驱动的方法，工具和干预措施， 伦理，多层次，社区参与的研究，解决MH和少数民族在艾滋病毒的健康差距。 为新的UM D-ARC提出的发展活动的总体目标是增加 当地MH艾滋病毒/艾滋病研究与中心主题和UM有关艾滋病毒/艾滋病的战略目标一致， 将提供强有力的机构支持。这一结构有助于实现我们的总体目标，即 建立发展中心，并通过促进减轻MH影响的研究来发展， 在艾滋病毒预防和治疗的整个过程中，少数群体的健康差距。UM D-ARC具有独特的 在最需要的受影响最严重的人群中开展艾滋病毒高影响研究的潜力， 艾滋病毒预防和治疗连续性下降的最大风险。

Project Summary (Overall) This application from the University of Miami (UM) for a Developmental AIDS Research Center (UM D- ARC) proposes to establish a behavioral science hub advancing mental health (MH) HIV research in a US region hardest hit by HIV/AIDS. The over-arching Center theme, “Reducing the Impact of Mental Health and Minority Health Disparities across the HIV Prevention and Care Continua,” is directly relevant to the uncontrolled HIV/AIDS epidemic in the Greater Miami area, and this developmental funding will provide a pathway for dynamic growth to a subsequent full ARC application. Over the initial funding period, we will consolidate, coordinate, and augment institutional resources as well as develop and expand regional and national collaborations. Miami has the highest HIV incidence and prevalence of any US city and fares worst, geographically, on every CDC indicator of HIV impact. Developing a D-ARC focused on MH at UM is also of high public health significance, as Miami’s diverse populations face significant MH disparities, making the area an ideal setting for MH research across diverse populations disproportionately affected by the epidemic. The organization of the UM D-ARC Cores represents a logical and innovative approach to establishing a D-ARC in an institution that has a growing cadre of behavioral scientists and a strategic goal of increasing HIV research. We propose the required Administrative (Admin) Core and Developmental (Dev) Core and two (rather than the required one) complementary Research Cores: a Methods Core and a Mental Health Disparities (MHD) Core. The Admin Core will embody Center leadership, governance, and strategic planning and coordinate the bi-directional community engagement activities that are key to the work of all Cores. The Dev Core will focus on awarding pilot studies and mentoring early stage investigators. The Methods Core will provide innovative research design, biostatistical, and data management expertise and collaborate with the MHD Core to construct, expand, and maintain Center Common Data Elements (CDE), consent-to-contact databases, and a REDCap measures library to maximize resource sharing. The MHD Core will provide expertise and resources to promote culturally competent, theory-driven approaches, tools, and interventions in ethical, multi-level, community-engaged research addressing MH and minority health disparities in HIV. The developmental activities proposed for the new UM D-ARC have the overarching goal of increasing local MH HIV/AIDS research consistent with the center theme and UM strategic goals regarding HIV/AIDS and will leverage strong institutional support. This structure allows for attainment of our Overall Aims, which are to establish the Developmental Center, and to grow by promoting research that mitigates the impact of MH and minority health disparities across the HIV prevention and treatment continuum. The UM D-ARC has the unique potential for high-impact research addressing HIV among hardest-hit populations in greatest need and at greatest risk for falling off of the HIV prevention and treatment continua.