Building on Needle Exchange to Optimize HIV Prevention/Treatment

以针具交换为基础，优化艾滋病毒预防/治疗

• 批准号: 10269983
• 负责人: GREGORY M LUCAS
• 金额: $ 50.9万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10269983
• 关键词: AIDS prevention; Accident and Emergency department; Address; Aftercare; Baltimore; Black Populations; COVID-19; COVID-19 impact; COVID-19 pandemic; COVID-19 patient; COVID-19 testing; Characteristics; Cities; Clinical; Code; Collaborations; Communication; Communities; Community Health Systems; Complex; Consolidated Framework for Implementation Research; Custom; Data; Data Collection; Diagnostic; Diagnostic Reagent Kits; Elements; Facebook; Family; Feedback; Food; Future; Glare; Goals; Grant; HIV; Health; Health Status; Health system; Healthcare; Home; Hotlines; Hour; Household; Human immunodeficiency virus test; Immigrant; Immigration; Income; Insurance; Intervention; Interview; Investigation; Job loss; Laboratories; Latino; Latino Population; Link; Maryland; Medicine; Methodology; Methods; Modality; Modeling; Needle-Exchange Programs; Not Hispanic or Latino; Online Systems; Outcome; Patients; Persons; PhenX Toolkit; Population; Process; Protocols documentation; RADx Underserved Populations; Reach Effectiveness Adoption Implementation and Maintenance; Religion and Spirituality; Research Personnel; Research Project Grants; Research Support; Resources; Risk; SARS-CoV-2 positive; Services; Site; Social Work; Stigmatization; Structure; Test Result; Testing; Time; Trust; Viral; Work; base; bilingualism; care systems; community based research; community partnership; community setting; data sharing; diagnostic technologies; disparity reduction; diversity and inclusion; experience; follow-up; health equity; implementation determinants; implementation evaluation; implementation outcomes; implementation science; implementation study; innovation; marginalized community; member; multidisciplinary; novel; peer; peer support; phase 1 testing; programs; rapid test; response; self testing; skills; social health determinants; testing uptake; uptake; web site

PROJECT SUMMARY Latinos are among the most heavily impacted communities by the COVID-19 pandemic in the US, with more than 3 times higher rate than non-Hispanic whites. To address this disparity, this team of investigators and community partners has established a multi-pronged approach that leverages the skill set of trusted bilingual/bicultural peer navigators (or promotoras) to address social determinants of health (SDOH) that create barriers to testing (such as lack of insurance, immigration status, stigmatization or loss of job/income), and to expand access to free COVID-19 testing in community settings. Our preliminary findings show that leveraging the promotora model for timely delivery of results (within 48 hours), paired with rapid linkage of COVID-19 positive patients to critical services (including clinical follow-up, food delivery, cash assistance, and/or isolation hotel), and referral of contacts for testing, increased acceptability and uptake of COVID-19 testing in a heavily impacted Latino community. The overall goal of this Phase I Testing Research Project called Juntos (Together) is to work closely with our community partners to systematically evaluate and refine current COVID-19 testing strategies, and to implement and evaluate innovative customized strategies to rapidly increase reach, access, acceptance, uptake, and sustainment of FDA-authorized/approved diagnostics (especially viral tests) for this highly vulnerable and health care marginalized community. Leveraging community partnerships and prior experience implementing an HIV testing campaign, we will develop and evaluate a customized Juntos COVID- 19 testing campaign to address specific common concerns in the Latino community and link users to existing Johns Hopkins COVID-19 community testing sites and to new options, including home-based and/or self- testing kits and rapid tests (Aim 1). To assess the overall impact of the Juntos COVID-19 Testing Project, we will rely on the latest in causal inference methods for evaluating population-level health interventions and implement a synthetic control analysis to compare testing uptake and positivity rate among Latinos in Baltimore City (intervention site) as compared to control zip codes across Maryland. (Aim 2). Finally, informed by Consolidated Framework for Implementation Research (CFIR) and RE-AIM framework, we will assess the implementation determinants, mechanisms, and outcomes of existing and novel Juntos testing interventions to inform future broad-scale implementation (Aim 3). We have assembled a multi-disciplinary team with methodological expertise in implementation science, community-based research, and laboratory medicine, and have a mature and long-standing collaboration with our partners at Esperanza Center, Casa de Maryland, the Mayor's Office of Immigrant Affairs, and religious leaders. Our team is enthusiastic to propose this implementation study to enhance access to testing for the Latino community, and will actively coordinate and share data and protocols with other grantees, the CDCC, and other research supported by the RADx-UP program.

项目摘要 拉丁裔是美国受COVID-19大流行影响最严重的社区之一， 比非西班牙裔白人高3倍以上。为了解决这一差异，这支调查团队和 社区合作伙伴已经建立了一种多管齐下的方法， 双语/双文化同伴导航员（或促进者），以解决健康的社会决定因素（SDOH）， 检测的障碍（如缺乏保险、移民身份、污名化或失去工作/收入），以及 在社区环境中扩大免费COVID-19检测的可及性。我们的初步研究结果表明， 启动子模型，用于及时提供结果（48小时内），并与COVID-19的快速联系相结合 积极的病人到关键服务（包括临床随访，食品交付，现金援助，和/或隔离 酒店），并转介接触者进行检测，提高了COVID-19检测的可接受性和接受率， 影响拉丁美洲社区。这个第一阶段测试研究项目的总体目标称为Juntos（一起） 是与我们的社区合作伙伴密切合作，系统地评估和完善当前的COVID-19检测 战略，并实施和评估创新的定制战略，以迅速扩大覆盖面，获得， 接受、吸收和维持FDA授权/批准的诊断（尤其是病毒检测） 高度脆弱和保健边缘化社区。利用社区合作伙伴关系和 经验实施艾滋病毒检测活动，我们将制定和评估定制的Juntos COVID- 19测试活动，以解决拉丁美洲社区的具体共同关切，并将用户与现有的 约翰霍普金斯COVID-19社区检测点和新的选择，包括基于家庭和/或自我- 测试包和快速测试（目标1）。为了评估Juntos COVID-19检测项目的整体影响，我们 将依靠最新的因果推理方法来评估人口水平的健康干预措施， 实施综合控制分析以比较巴尔的摩拉丁美洲人测试吸收和阳性率 城市（干预地点）与马里兰州的对照邮政编码相比。(Aim 2）。最后，通知 实施研究综合框架（CFIR）和RE-AIM框架，我们将评估 现有和新的Juntos测试干预措施的实施决定因素、机制和结果， 为今后大规模执行提供信息（目标3）。我们组建了一个多学科团队， 在实施科学，基于社区的研究和实验室医学的方法学专业知识，以及 有一个成熟和长期的合作伙伴在埃斯佩兰萨中心，卡萨德马里兰州， 市长移民事务办公室和宗教领袖。我们的团队很热心地提出这个 执行研究，以提高获得测试的拉丁美洲社区，并将积极协调， 与其他受资助者、CDCC和其他由RADx-UP支持的研究共享数据和协议 程序.

项目成果

High Uptake and Series Completion of COVID-19 Vaccine at Community-Based Vaccination for Latinos With Limited English Proficiency.

在基于社区的拉丁裔疫苗接种中，英语能力有限的拉丁裔疫苗接种Covid-19疫苗的高吸收和系列完成。

• DOI: 10.1097/phh.0000000000001625
• 发表时间: 2022-11-01
• 期刊: JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE
• 影响因子: 3.3
• 作者: Bigelow, Benjamin F.;Saxton, Ronald E.;Martinez, Diego A.;Flores-Miller, Alejandra;Shin, Jong M.;Parent, Cassandra;Williams, Samantha;Phillips, Katherine Hartman;Yang, Cui;Page, Kathleen Raquel
• 通讯作者: Page, Kathleen Raquel

Racial and Ethnic Disparities in Glycemic Control Among Patients With SARS-CoV-2 in the Baltimore-Washington, District of Columbia Region.

• DOI: 10.1016/j.focus.2023.100156
• 发表时间: 2024-02
• 期刊: AJPM focus
• 作者: Parent, Cassandra;Martinez, Diego A;Venkataramani, Maya;Yang, Cui;Page, Kathleen R
• 通讯作者: Page, Kathleen R

Responding to the Disproportionate Impact of COVID-19 Among Latinx Patients in Baltimore: The JHM Latinx Anchor Strategy.

应对巴尔的摩拉丁裔患者中 COVID-19 的不成比例的影响：JHM 拉丁裔锚定策略。

• DOI: 10.1089/hs.2021.0203
• 发表时间: 2022
• 期刊: Health security
• 影响因子: 3.3
• 作者: Page,KathleenR;Wilson,Alicia;Phillips,KatherineHartmann;Flores-Miller,Alejandra;Vazquez,MonicaGuerrero;Bigelow,BenjaminF;Bryan,JacquelineN;Moore,Adrianna;Tolson,Tina;McCann,Nicki;Sisson,StephenD;Parker,Ann;Brigham,Emily;Ste
• 通讯作者: Ste

COVID-19 vaccine hesitancy among undocumented migrants during the early phase of the vaccination campaign: a multicentric cross-sectional study.

• DOI: 10.1136/bmjopen-2021-056591
• 发表时间: 2022-03-17
• 期刊: BMJ open
• 影响因子: 2.9
• 作者: Page KR;Genovese E;Franchi M;Cella S;Fiorini G;Tlili R;Salazar S;Duvoisin A;Cailhol J;Jackson Y
• 通讯作者: Jackson Y

A Crowdsourcing Open Contest to Design a Latino-Specific COVID-19 Campaign: Mixed Methods Analysis.

• DOI: 10.2196/35764
• 发表时间: 2022-05-12
• 期刊: JMIR FORMATIVE RESEARCH
• 影响因子: 2.2
• 作者: Shah, Harita S.;Grieb, Suzanne Dolwick;Flores-Miller, Alejandra;Phillips, Katherine H.;Page, Kathleen R.;Cervantes, Ana;Yang, Cui
• 通讯作者: Yang, Cui