Administrative Core

项目摘要（管理核心） 拟议中的加速阿尔茨海默氏症人口研究中心（CAPRA）的目标是作为一个 国家资源，以促进和加速旨在向政府提供信息的观测研究， 卫生保健系统采取行动，以减少AD/ADRD的社会、经济和健康负担。实现这一 CAPRA需要一个管理基础设施，以支持及时、精心设计的研究， 复杂的人口和医疗保健数据，并结合了当地，国家和 化国际大CAPRA的行政核心将提供这种基础设施、管理和 这是实施《非洲和平与重建行动计划》战略愿景所必需的沟通和传播战略， 利用密歇根大学（UM）和其他机构的深厚专业知识， 在当地和全国范围内建立了研究人员，以启动AD/ADRD人群研究的新领域。做 因此，CAPRA将资助和支持试点研究，提供培训材料、工具，并在某些情况下提供 与AD/ADRD相关的二级数据，还将建立专家网络， 合作CAPRA的结构和管理将包括四个核心（行政、试点、外部网络 和研究资源核心）、一个指导委员会和一个外部咨询小组，全部由 跨学科和专业领域的调查人员，将产生必要的想法的多样性， 应对AD/ADRD带来的复杂挑战。CAPRA实力的基础是 由领导团队和计划的附属机构代表的专业知识，提供的机构支持 由UM，并与其他老龄中心和外部UM的合作。拜纳姆医生和朗加医生 行政核心领导人在相关学术，医疗保健，政策制定和 利益攸关方群体。CAPRA行政核心将发挥多项职能，包括： 咨询委员会;行政支持试点研究的决定过程;赠款管理和 跟踪;为提供技术支持的培训支持提供基础设施，并向公众开放 数据和算法;协调科学联网活动的面对面机会， 我们的子公司、内部和外部合作伙伴之间的沟通和参与战略，以及 决策者等利益相关者。拟议中的CAPRA有很大的机会和潜力，以加快 AD/ADRD的人口和卫生保健研究进展。CAPRA的成功取决于 由行政核心提供的基础设施、组织和管理。

Project Abstract (Admin Core) The goal of the proposed Center to Accelerate Population Research in Alzheimer’s (CAPRA) is to serve as a national resource to promote and accelerate observational studies that aim to inform government and healthcare system actions to reduce the social, economic, and health burden of AD/ADRD. To achieve this objective, CAPRA requires an administrative infrastructure that supports timely, well-designed studies using complex population and healthcare data and incorporates input from experts locally, nationally, and internationally. The Administrative Core for CAPRA will provide this infrastructure, management, and communication and dissemination strategy necessary to implement the strategic vision of the CAPRA which is to leverage the deep expertise at the University of Michigan (UM) and other institutions to enable new and established investigators locally and nationally to initiate novel areas of AD/ADRD population research. To do so, CAPRA will fund and support pilot studies, provide training materials, tools, and in some cases access to secondary data relevant to AD/ADRD, and will also develop networks of experts with whom to consult and collaborate. CAPRA’s structure and governance will include four Cores (Administrative, Pilot, External Network and Research Resources Cores), a Steering Committee and an External Advisory Panel, all composed of investigators across disciplines and areas of expertise that will generate the diversity of ideas necessary to address the complex challenges posed by AD/ADRD. The foundation of CAPRA’s strength is the depth of expertise that is represented by the leadership team and planned affiliates, the institutional supports provided by UM, and the collaboration with the other aging centers at and outside UM. Drs. Bynum and Langa as the Administrative core leaders have broad connections across relevant academic, healthcare, policy-making and stakeholder groups. The CAPRA Administrative Core will serve several functions including: management of advisory committees; administratively supporting the pilot study decision process; grants management and tracking; providing an infrastructure for delivery of technology-enabled training support and publicly accessible data and algorithms; coordination of in-person opportunities for scientific networking activities, and carrying out the communications and engagement strategy across our affiliates, internal and external partners, and stakeholders such as policy makers. The proposed CAPRA has great opportunity and potential to accelerate the advance of the science of population and healthcare research in AD/ADRD. CAPRA’s success depends on the infrastructure, organization and management provided by the Administrative Core.