Enabling dairy farmers to conduct onsite, early stage monitoring of bovine mastitis – Assessing a route to market for a portable PCR workflow.

使奶农能够对牛乳腺炎进行现场早期监测 – 评估便携式 PCR 工作流程的市场途径。

基本信息

批准号：
10043257
负责人：
金额：
$ 6.22万
依托单位：
BENTO BIOWORKS LTD.
依托单位国家：
英国
项目类别：
Grant for R&D
财政年份：
2022
资助国家：
英国
起止时间：
2022 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=10043257
关键词：
Enabling dairy farmers conduct onsite

项目摘要

A big challenge for all dairy farms is managing the health of their livestock. An infection called mastitis causes farmers more economic losses than any other cattle disease.Mastitis is an udder infection that results in a dairy animal producing milk at lower quantity and quality. When an infection is detected, the typical approach is to treat the entire group of animals with antibiotics, including the cows that don't show symptoms. This is unhealthy for the cows that do not have the disease, and contributes to antibiotic resistance. Due to the advanced infection, the farmer loses the income expected from the lost milk.When caught early, the infection can be treated without antibiotics, and prevented from spreading. The most reliable diagnostic method is PCR technology, the same method used to identify COVID. However these diagnostic tests are done by external laboratories, and they can be very expensive and slow.Bento Lab is a portable PCR workstation that is easy to set-up. The applications of our existing customers range from decentralised malaria research to national fungi genomics surveys. We recently developed an application kit that enables bird conservationists to conduct a DNA test for bird sexing within a few hours of training.With the support of Innovate UK, we will use our existing technology to develop a package for dairy farmers to monitor their cattle, and catch infections early.

所有奶牛场的挑战是管理牲畜的健康。一种称为乳腺炎的感染会导致农民比任何其他牛病更大的经济损失。乳腺炎是一种乳腺炎感染，导致乳制品动物以较低的数量和质量产生牛奶。当检测到感染时，典型的方法是用抗生素治疗整个动物，包括未表现出症状的母牛。对于没有疾病的母牛并有助于抗生素耐药性，这是不健康的。由于感染了晚期感染，农民失去了损失的牛奶预期的收入。当提早捕获时，可以在没有抗生素的情况下治疗感染，并阻止传播。最可靠的诊断方法是PCR技术，该方法与识别共同的方法相同。但是，这些诊断测试是由外部实验室完成的，它们可能非常昂贵且缓慢。BentoLab是一种便携式PCR工作站，易于设置。我们现有客户的应用范围从分散的疟疾研究到国家真菌基因组学调查。我们最近开发了一个应用程序套件，该套件使鸟类保护主义者能够在培训的几个小时内进行鸟类性别的DNA测试。在英国创新的英国的支持下，我们将使用现有技术为奶农开发一个包装，以监测牛的牛，并尽早感染感染。