Administration - Resource for Molecular Imaging Agents in Precision Medicine

BTRC行政和管理 摘要 精准医学分子成像试剂资源的管理核心将协调所有 BTRC的活动，包括为合作和服务项目提供联络，以确保其 持续的生产力。这一核心将设在核能司的组织结构内。 放射科内的医学和分子成像。该核心还将负责 组织监督，即内部和外部科学咨询委员会的会议。在……里面 与工作人员在培训和传播方面的合作核心它将是组织科学 与研发和发展相关的会议和务虚会，继续努力保持其凝聚力和使命感。 这个核心的PI庞珀博士在分子显像剂的合成和开发方面经验丰富 精通基础研究和临床医学，尤其是放射学 和核医学。他在同时运行NIH资助的项目和在 与约翰·霍普金斯大学以外的调查人员合作。庞珀医生将负责日常手术 与四个研发及发展署的私人投资总监紧密合作，组成 BTRC。研发部门的PI在约翰·霍普金斯医学院百老汇校区近距离工作 为每两个月举行一次的面对面会议提供便利。因为这些PI是 由于已经在其他项目上进行协作，非正式会议将更频繁地举行，如果不是每天举行的话。 执行委员会将每年向执行委员会和东非委员会寻求进一步的投入，每项投入由6个单位抵消。 月间隔。咨询委员会和咨询委员会将分别由当地专家和校外专家组成， 用于各种模式的分子显像剂的表征、验证和实施。作为 BTRC的生物学主题是癌症、炎症和免疫之间的关系，我们将至少有 一名IAC和一名EAC成员致力于免疫学。在这个核心，我们还将有两名顾问，每人 他是免疫学的国际领先者。选管会还将有一名成员担任 病人代言人。选管会的会议纪要将以年度进度报告的形式提供给NIBIB。确实有 约翰·霍普金斯大学监督的许多其他非正式方面，行政核心将与之联系， 包括放射性药物研究委员会、动物护理和使用委员会、临床 西德尼·基梅尔综合癌症中心研究室和机构审查委员会。这个 行政核心将支持研发人员开发和维护相关动物和人类 协议，在适当的地方。 BTRC的财务方面将通过行政核心受到密切监测。有很强的 向BTRC提供的机构支持，包括院长办公室和临时办公室所描述的财务支持 约翰霍普金斯大学放射科主任。

BTRC ADMINISTRATION and MANAGEMENT SUMMARY The Administrative Core of the Resource for Molecular Imaging Agents in Precision Medicine will coordinate all activities of the BTRC including provision of a liaison to the Collaborative and Service Projects to assure their sustained productivity. This Core will be housed within the organizational structure of the Division of Nuclear Medicine and Molecular Imaging within the Department of Radiology. This Core will also be responsible for organizing oversight, namely, meetings of the Internal and External Scientific Advisory Committees. In collaboration with staff in the Training and Dissemination Core It will be the focal point for organization of scientific meetings and retreats related to the TR&Ds in a continual effort to maintain their cohesion and sense of purpose. The PI of this Core, Dr. Pomper, is experienced in the synthesis and development of molecular imaging agents for a variety of modalities and is conversant in both basic research and clinical medicine, particularly radiology and nuclear medicine. He has substantial experience in running NIH-funded programs in parallel and in collaboration with investigators external to Johns Hopkins. Dr. Pomper will be responsible for routine operation of this Core in close collaboration with the PIs of the four TR&Ds, which will form an Executive Committee of the BTRC. The PIs of the TR&Ds work in close proximity on the Broadway Campus of Johns Hopkins Medical Institutions, facilitating face-to-face meetings, which will occur formally on a bi-monthly basis. As these PIs are already collaborating on other projects, informal meetings will occur much more frequently if not on a daily basis. The Executive Committee will turn to the IAC and EAC for further input on an annual basis, each, offset by a six month interval. The IAC and EAC will be comprised of local and extramural experts, respectively, in the synthesis, characterization, validation and implementation of molecular imaging agents for a variety of modalities. As the biological theme of the BTRC is relationships between cancer, inflammation and immunity, we will have at least one IAC and one EAC member dedicated to immunology. In this Core we will also have two consultants, each of whom is an international leader in immunology. The EAC will also have one member who will serve as a patient advocate. Minutes of the EAC meetings will be provided in annual progress reports to NIBIB. There are many other informal aspects of oversight at Johns Hopkins with which the Administrative Core will interface, including the Radioactive Drug Research Committee, the Animal Care and Use Committee, the Clinical Research Office of the Sidney Kimmel Comprehensive Cancer Center and the Institutional Review Board. The Administrative Core will support the TR&Ds in development and maintenance of relevant animal and human protocols, where appropriate. Financial aspects of the BTRC will be closely monitored through the Administrative Core. There is strong institutional support, including financial support, for the BTRC as described by the Dean's office and the Interim Director of Radiology at Johns Hopkins.