Administration - Resource for Molecular Imaging Agents in Precision Medicine

管理 - 精准医学中分子成像剂的资源

• 批准号: 10226207
• 负责人: MARTIN G POMPER
• 金额: $ 7.79万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10226207
• 关键词: Advisory Committees; Advocate; Animal Care and Use Committees; Animals; Appointment; Basic Science; Biological; Clinical Medicine; Clinical Research; Collaborations; Comprehensive Cancer Center; Development; Discipline of Nuclear Medicine; Engineering; Environment; Extramural Activities; Financial Activity; Financial Support; Funding; Guidelines; Human; Immunity; Immunology; Inflammation; Institutes; Institution; Institutional Review Boards; International; Maintenance; Malignant Neoplasms; Medical; Methods; Modality; Monitor; National Institute of Biomedical Imaging and Bioengineering; Patients; Productivity; Progress Reports; Protocols documentation; Radiology Specialty; Radiopharmaceuticals; Research; Research Personnel; Resources; Running; Schools; Services; Training; United States National Institutes of Health; Validation; Work; cohesion; experience; imaging agent; medical schools; meetings; member; molecular imaging; nuclear division; operation; organizational structure; precision medicine; programs; scientific organization

BTRC ADMINISTRATION and MANAGEMENT SUMMARY The Administrative Core of the Resource for Molecular Imaging Agents in Precision Medicine will coordinate all activities of the BTRC including provision of a liaison to the Collaborative and Service Projects to assure their sustained productivity. This Core will be housed within the organizational structure of the Division of Nuclear Medicine and Molecular Imaging within the Department of Radiology. This Core will also be responsible for organizing oversight, namely, meetings of the Internal and External Scientific Advisory Committees. In collaboration with staff in the Training and Dissemination Core It will be the focal point for organization of scientific meetings and retreats related to the TR&Ds in a continual effort to maintain their cohesion and sense of purpose. The PI of this Core, Dr. Pomper, is experienced in the synthesis and development of molecular imaging agents for a variety of modalities and is conversant in both basic research and clinical medicine, particularly radiology and nuclear medicine. He has substantial experience in running NIH-funded programs in parallel and in collaboration with investigators external to Johns Hopkins. Dr. Pomper will be responsible for routine operation of this Core in close collaboration with the PIs of the four TR&Ds, which will form an Executive Committee of the BTRC. The PIs of the TR&Ds work in close proximity on the Broadway Campus of Johns Hopkins Medical Institutions, facilitating face-to-face meetings, which will occur formally on a bi-monthly basis. As these PIs are already collaborating on other projects, informal meetings will occur much more frequently if not on a daily basis. The Executive Committee will turn to the IAC and EAC for further input on an annual basis, each, offset by a six month interval. The IAC and EAC will be comprised of local and extramural experts, respectively, in the synthesis, characterization, validation and implementation of molecular imaging agents for a variety of modalities. As the biological theme of the BTRC is relationships between cancer, inflammation and immunity, we will have at least one IAC and one EAC member dedicated to immunology. In this Core we will also have two consultants, each of whom is an international leader in immunology. The EAC will also have one member who will serve as a patient advocate. Minutes of the EAC meetings will be provided in annual progress reports to NIBIB. There are many other informal aspects of oversight at Johns Hopkins with which the Administrative Core will interface, including the Radioactive Drug Research Committee, the Animal Care and Use Committee, the Clinical Research Office of the Sidney Kimmel Comprehensive Cancer Center and the Institutional Review Board. The Administrative Core will support the TR&Ds in development and maintenance of relevant animal and human protocols, where appropriate. Financial aspects of the BTRC will be closely monitored through the Administrative Core. There is strong institutional support, including financial support, for the BTRC as described by the Dean's office and the Interim Director of Radiology at Johns Hopkins.

BTRC 行政管理 概括 精准医学分子影像剂资源的管理核心将协调所有 BTRC 的活动，包括为合作和服务项目提供联络，以确保他们的 持续的生产力。该核心将设在核部门的组织结构内 放射科内的医学和分子成像。该核心还将负责 组织监督，即内部和外部科学咨询委员会会议。在 与培训和传播核心工作人员的合作它将成为组织科学活动的焦点 与 TR&D 相关的会议和务虚会，不断努力保持其凝聚力和使命感。 该核心PI Pomper博士在分子显像剂的合成和开发方面拥有丰富的经验 适用于多种模式，熟悉基础研究和临床医学，特别是放射学 和核医学。他在并行和独立运行 NIH 资助的项目方面拥有丰富的经验。 与约翰霍普金斯大学外部的研究人员合作。 Pomper博士将负责日常操作 该核心与四个 TR&D 的 PI 密切合作，这将组成一个执行委员会 BTRC。 TR&D 的 PI 在约翰·霍普金斯医学院百老汇校区附近工作 机构，促进面对面会议，该会议将每两个月正式举行一次。由于这些 PI 是 由于已经在其他项目上进行了合作，非正式会议即使不是每天举行，也会更加频繁地举行。 执行委员会将每年向 IAC 和 EAC 寻求进一步的意见，各自抵消六次 月间隔。 IAC 和 EAC 将分别由本地和校外专家组成，负责综合、 用于多种模式的分子成像剂的表征、验证和实施。作为 BTRC的生物学主题是癌症、炎症和免疫之间的关系，我们至少会有 一名 IAC 和一名 EAC 成员致力于免疫学。在这个核心中，我们还将有两名顾问，每人 其中免疫学领域的国际领先者。选管会还将有一名成员担任 患者倡导者。 EAC 会议纪要将在向 NIBIB 提交的年度进度报告中提供。有 约翰·霍普金斯大学的许多其他非正式监督方面将与行政核心进行交互， 包括放射性药物研究委员会、动物护理和使用委员会、临床委员会 悉尼金梅尔综合癌症中心研究办公室和机构审查委员会。这 行政核心将支持 TR&D 开发和维护相关动物和人类 协议（如适用）。 BTRC 的财务方面将通过行政核心进行密切监控。有很强的 如院长办公室和临时委员会所述，为 BTRC 提供机构支持，包括财政支持 约翰·霍普金斯大学放射科主任。