TOPIC #411 - PHASE I SBIR CONTRACT - AN IMAGEDX BASED PLATFORM FOR COMPREHENSIVE DE-IDENTIFICATION OF WSI DATA

本提案的目的是开发一种去识别工具，能够确保整个载玻片成像的依从性 (WSI)从多个供应商的数据到HIPAA隐私规则。这样的去识别工具将用于更有效地 并全面地去识别商业和政府资助的研究人员所需的大型数据存储。去认同 将开发为ImageDx De-ID模块，扩展了目前Reveal Biosciences的产品组合， 提供全面计算病理学服务的商业ImageDx模块。以下目标将是 使用我们的设计驱动开发流程完成：（1）景观分析-确定供应商，文件类型和PHI （2）识别和提供数据集-从现有的去识别载玻片、载玻片标签机和内部提供的数据集 扫描仪;（3）识别、打开、显示和更改WSI文件-开发概念验证De-ID接口， 在多个供应商的WSI文件中打开和更改PHI信息;以及（3）识别数据集和文件类型， 第二阶段。项目最终交付成果是一个ImageDx De-ID模块，能够识别、打开、显示和 更改来自多个WSI扫描仪供应商的PHI字段。

The objective of this proposal is to develop a de-identification tool capable of ensuring adherence of whole slide imaging (WSI) data from multiple vendors to the HIPAA Privacy Rule. Such a de-identification tool will be used to more efficiently and comprehensively de-identify the large data stores required by commercial and government funded researchers. Deidentification will be developed as the ImageDx De-ID module, extending the current Reveal Biosciences portfolio of commercial ImageDx modules providing comprehensive computation pathology services. The following Aims will be completed using our Design Driven Development process: (1) Landscape analysis – to identify vendors, filetypes, and PHI fields; (2) Identify and provide data sets – datasets provided from existing de-identified slides, slide labelers, and inhouse scanners; (3) Recognize, open, display, and alter WSI files – develop proof of concept De-ID interface capable of opening and altering PHI information in WSI files across multiple vendors; and (3) Identify data sets and file types for Phase II. The end of project deliverable is an ImageDx De-ID module capable of recognizing, opening, displaying, and altering PHI fields from multiple WSI scanner vendors.