FY20 PHASE I SBIR CONTRACT - TOPIC 401 - PHASE I SBIR CONTRACT QUANTITATIVE BIOMIMETIC MRI BREAST TISSUE AND TUMOR PHANTOM: TOWARD A COMPREHENSIVE PHA
FY20 PHASE I SBIR CONTRACT - TOPIC 401 - PHASE I SBIR CONTRACT QUANTITATIVE BIOMIMETIC MRI BREAST TISSUE AND TUMOR PHANTOM: TOWARD A COMPREHENSIVE PHA
批准号:
10274011
负责人:
TODOR KARAULANOV
金额:
$39.98万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
已结题
起止时间:
2020-09-16 至 2021-06-15
关键词:
3D PrintAddressBiomimeticsBreast Cancer Early DetectionBreast Magnetic Resonance ImagingClinical ResearchContractsDevelopmentDevelopment PlansDiagnostic Neoplasm StagingEnsureEvaluationExcisionFeedbackLymphMagnetic Resonance ImagingMammary Gland ParenchymaMammary NeoplasmsMethodsMorbidity - disease rateNodalPatientsPerformancePhasePrimary NeoplasmProcessReportingReproducibilityResearchResourcesSan FranciscoScanningSmall Business Innovation Research GrantStructureSurveysTechniquesTimeTissuesUpdateValidationWashingtonbasebioprintingimprovedlymph node biopsylymph nodesmalignant breast neoplasmpersonalized medicineside effectstatisticssuccesstooltumor progression
中文摘要
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英文摘要
Research statistics have confirmed that breast cancer early detection saves lives. It is important
that the patient is staged properly with the lowest possible side effects (morbidity). The best personalized treatment
with almost immediate feedback on efficacy is critical to addressing the spread of breast cancer in
a timely manner. Creation of a biomimetic quantitative MRI platform to guide the optimization of
MRI scanners will enable and improve early breast cancer detection by providing a basis for
quantitative assessment of tumor progression during treatment, and providing a means for cancer
staging based on qMRI biomimics of primary tumor and lymph nodes. It is believed that this will
drive research on using MRI to assess lymph nodal status and ultimately avoid many of the currently
required lymph node biopsies and lymph node removal.
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